Plasmalemmal VDAC-1 corroborated as amyloid Aß-receptor

Biophysical Alterations in Lipid Rafts from Human Cerebral Cortex Associate with Increased BACE1/AβPP Interaction in Early Stages of Alzheimer's Disease

(2018) Mario Díaz et al.   JOURNAL OF ALZHEIMERS DISEASE

Phase 3 solanezumab trials: Secondary outcomes in mild Alzheimer's disease patients

(2016) Eric R. Siemers et al.   Alzheimers & Dementia

Cancer and Dementia

(2015) Mary Ganguli   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Phosphorylation, nitrosation and plasminogen K3 modulation make VDAC-1 lucid as part of the extrinsic apoptotic pathway—Resulting thesis: Native VDAC-1 indispensible for finalisation of its 3D structure

(2015) Friedrich P. Thinnes   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Modulation of the mitochondrial voltage dependent anion channel (VDAC) by curcumin

(2015) Debanjan Tewari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Reduction of Glucose Metabolism in Olfactory Bulb is an Earlier Alzheimer's Disease-related Biomarker in 5XFAD Mice

(2015) Xiao-Chun Chen et al.   CHINESE MEDICAL JOURNAL

A New Fungal Diterpene Induces VDAC1-dependent Apoptosis in Bax/Bak-deficient Cells

(2015) Li Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An N-terminal antibody promotes the transformation of amyloid fibrils into oligomers and enhances the neurotoxicity of amyloid-beta: the dust-raising effect

(2015) Yu-Hui Liu et al.   Journal of Neuroinflammation

Plasma amyloid β—quo vadis?

(2015) Henrik Zetterberg   NEUROBIOLOGY OF AGING

Association of plasma β-amyloid with MRI markers of structural brain aging the 3-City Dijon study

(2015) Sara Kaffashian et al.   NEUROBIOLOGY OF AGING

P-glycoprotein expression and amyloid accumulation in human aging and Alzheimer's disease: preliminary observations

(2015) Catherine Chiu et al.   NEUROBIOLOGY OF AGING

After all, plasmalemmal expression of type-1 VDAC can be understood. Phosphorylation, nitrosylation, and channel modulators work together in vertebrate cell volume regulation and either apoptotic pathway

(2015) Friedrich P. Thinnes   Frontiers in Physiology

Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect

(2015) Lloyd A. Demetrius et al.   Frontiers in Physiology

Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus

(2015) Ying Y. Jean et al.   Jove-Journal of Visualized Experiments

Plasminogen Kringle 5 Induces Endothelial Cell Apoptosis by Triggering a Voltage-dependent Anion Channel 1 (VDAC1) Positive Feedback Loop

(2014) Lei Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Oligomeric States of the Purified Sigma-1 Receptor Are Stabilized by Ligands

(2014) Katarzyna A. Gromek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered lipid composition in cortical lipid rafts occurs at early stages of sporadic Alzheimer's disease and facilitates APP/BACE1 interactions

(2014) Noemí Fabelo et al.   NEUROBIOLOGY OF AGING

Aβ promotes VDAC1 channel dephosphorylation in neuronal lipid rafts. Relevance to the mechanisms of neurotoxicity in Alzheimer’s disease

(2014) C. Fernandez-Echevarria et al.   NEUROSCIENCE

Prognostic Value of Plasma β-Amyloid Levels in Patients With Acute Intracerebral Hemorrhage

(2014) Joan Martí-Fàbregas et al.   STROKE

Amyloid beta-induced glycogen synthase kinase 3β phosphorylated VDAC1 in Alzheimer's disease: Implications for synaptic dysfunction and neuronal damage

(2013) P. Hemachandra Reddy   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

VDAC1-based peptides: novel pro-apoptotic agents and potential therapeutics for B-cell chronic lymphocytic leukemia

(2013) T Prezma et al.   Cell Death & Disease

Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease

(2012) M. Manczak et al.   HUMAN MOLECULAR GENETICS

Alzheimer disease controls cancer — Concerning the apoptogenic interaction of cell membrane-standing type-1 VDAC and amyloid peptides via GxxxG motifs

(2012) Friedrich P. Thinnes   MOLECULAR GENETICS AND METABOLISM

Why cancer survivors have a lower risk of Alzheimer disease

(2012) Friedrich P. Thinnes   MOLECULAR GENETICS AND METABOLISM

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

(2011) Maria Manczak et al.   HUMAN MOLECULAR GENETICS

Signalosomes in the brain: relevance in the development of certain neuropathologies such as Alzheimer’s disease

(2011) Raquel Marin   Frontiers in Physiology

Functional deprivation promotes amyloid plaque pathogenesis in Tg2576 mouse olfactory bulb and piriform cortex

(2010) Xue-Mei Zhang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Aberrant Amyloid Precursor Protein (APP) Processing in Hereditary Forms of Alzheimer Disease Caused by APP Familial Alzheimer Disease Mutations Can Be Rescued by Mutations in the APP GxxxG Motif

(2010) Lisa-Marie Munter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid Aß , cut from APP by ß-secretase BACE1 and γ-secretase, induces apoptosis via opening type-1 porin/VDAC in cell membranes of hypometabolic cells—A basic model for the induction of apoptosis!?

(2010) Friedrich P. Thinnes   MOLECULAR GENETICS AND METABOLISM

VDAC and ERα interaction in caveolae from human cortex is altered in Alzheimer's disease

(2009) Cristina M. Ramírez et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Modulation of Aβ-induced neurotoxicity by estrogen receptor alpha and other associated proteins in lipid rafts

(2007) R MARIN et al.   STEROIDS