☆ 4.4 Letter

Amyloid A beta cut from APP by beta-secretase BACE1 and gamma-secretase, induces apoptosis via opening type-1 porin/VDAC in cell membranes of hypometabolic cells-A basic model for the induction of apoptosis!?

MOLECULAR GENETICS AND METABOLISM (2010)

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Journal

MOLECULAR GENETICS AND METABOLISM
Volume 101, Issue 2-3, Pages 301-303

Publisher

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ymgme.2010.07.007

Keywords

Apoptosis induction; Extrinsic pathway; Amyloid A beta; VDAC; Porin; Plasma lemma; Channel opening; Alzheimer; Down syndrome; Amyotrophic lateral sclerosis; ALS

Categories

Endocrinology & Metabolism Genetics & Heredity Medicine, Research & Experimental

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