Bioactive Lipids and Cationic Antimicrobial Peptides as New Potential Regulators for Trafficking of Bone Marrow-Derived Stem Cells in Patients with Acute Myocardial Infarction

Randomized, double-blind pilot study of transendocardial injection of autologous aldehyde dehydrogenase–bright stem cells in patients with ischemic heart failure

(2012) Emerson C. Perin et al.   AMERICAN HEART JOURNAL

S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release

(2012) K. Golan et al.   BLOOD

Ceramide-1-Phosphate Regulates Migration of Multipotent Stromal Cells and Endothelial Progenitor Cells-Implications for Tissue Regeneration

(2012) Chihwa Kim et al.   STEM CELLS

Paracrine Proangiopoietic Effects of Human Umbilical Cord Blood-Derived Purified CD133+ Cells—Implications for Stem Cell Therapies in Regenerative Medicine

(2012) Janina Ratajczak et al.   STEM CELLS AND DEVELOPMENT

S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart

(2011) Padmavathi Bandhuvula et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

COMP-Ang1 stimulates HIF-1 -mediated SDF-1 overexpression and recovers ischemic injury through BM-derived progenitor cell recruitment

(2011) S.-W. Youn et al.   BLOOD

Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice

(2011) J. G. Juarez et al.   BLOOD

Bone Marrow-Derived Cell Therapy Stimulates Endogenous Cardiomyocyte Progenitors and Promotes Cardiac Repair

(2011) Francesco S. Loffredo et al.   Cell Stem Cell

Plasma levels of sphingosine 1-phosphate are strongly correlated with haematocrit, but variably restored by red blood cell transfusions

(2011) Samy Selim et al.   CLINICAL SCIENCE

The bone marrow-expressed antimicrobial cationic peptide LL-37 enhances the responsiveness of hematopoietic stem progenitor cells to an SDF-1 gradient and accelerates their engraftment after transplantation

(2011) W Wu et al.   LEUKEMIA

Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow: a novel role for bioactive lipids and soluble C5b-C9 as homing factors

(2011) C H Kim et al.   LEUKEMIA

A novel perspective on stem cell homing and mobilization: review on bioactive lipids as potent chemoattractants and cationic peptides as underappreciated modulators of responsiveness to SDF-1 gradients

(2011) M Z Ratajczak et al.   LEUKEMIA

Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: can we translate stem cell-secreted paracrine factors and microvesicles into better therapeutic strategies?

(2011) M Z Ratajczak et al.   LEUKEMIA

Heart Disease and Stroke Statistics—2011 Update

(2010) Véronique L. Roger et al.   CIRCULATION

Role of Cardiac Myocyte CXCR4 Expression in Development and Left Ventricular Remodeling After Acute Myocardial Infarction

(2010) Udit Agarwal et al.   CIRCULATION RESEARCH

Heme oxygenase-1 and carbon monoxide promote neovascularization after myocardial infarction by modulating the expression of HIF-1α, SDF-1α and VEGF-B

(2010) Päivi Lakkisto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF-1/CXCR4 axis: Further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells

(2010) Ali Jalili et al.   EXPERIMENTAL HEMATOLOGY

Evidence of mobilization of pluripotent stem cells into peripheral blood of patients with myocardial ischemia

(2010) Ahmed Abdel-Latif et al.   EXPERIMENTAL HEMATOLOGY

Transplantation of expanded bone marrow-derived very small embryonic-like stem cells (VSEL-SCs) improves left ventricular function and remodelling after myocardial infarction

(2010) Ewa K. Zuba-Surma et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics

(2010) Shobha Thangada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Discovery, Biological Evaluation, and Structure−Activity Relationship of Amidine Based Sphingosine Kinase Inhibitors

(2010) Thomas P. Mathews et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex

(2010) M Z Ratajczak et al.   LEUKEMIA

Ceramide and ceramide 1-phosphate in health and disease

(2010) Lide Arana et al.   Lipids in Health and Disease

Complement C1q enhances homing-related responses of hematopoietic stem/progenitor cells

(2010) Ali Jalili et al.   TRANSFUSION

Enhanced mobilization of CD34+ progenitor cells expressing cell adhesion molecules in patients with STEMI

(2009) Michael Brehm et al.   Clinical Research in Cardiology

Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Intracoronary Infusion of Selected Population of Stem Cells in Acute Myocardial Infarction (REGENT) Trial

(2009) Michał Tendera et al.   EUROPEAN HEART JOURNAL

Down-regulation of S1P1Receptor Surface Expression by Protein Kinase C Inhibition

(2009) Sven-Christian Sensken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defective engraftment of C3aR−/− hematopoietic stem progenitor cells shows a novel role of the C3a–C3aR axis in bone marrow homing

(2009) M Wysoczynski et al.   LEUKEMIA

Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes

(2009) H M Lee et al.   LEUKEMIA

Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes

(2009) H M Lee et al.   LEUKEMIA

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Granulocyte colony-stimulating factor therapy for cardiac repair after acute myocardial infarction: A systematic review and meta-analysis of randomized controlled trials

(2008) Ahmed Abdel-Latif et al.   AMERICAN HEART JOURNAL

Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

(2008) Krishnan Venkataraman et al.   CIRCULATION RESEARCH

Characterization of long-term endogenous cardiac repair in children after heart transplantation

(2008) S. Rupp et al.   EUROPEAN HEART JOURNAL

Complement Activation and Cardiovascular Disease

(2008) M. Bjerre et al.   HORMONE AND METABOLIC RESEARCH

Stem Cell Mobilization by Granulocyte Colony-Stimulating Factor for Myocardial Recovery After Acute Myocardial Infarction

(2008) Dietlind Zohlnhöfer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mobilization of Bone Marrow-Derived Oct-4+ SSEA-4+ Very Small Embryonic-Like Stem Cells in Patients With Acute Myocardial Infarction

(2008) Wojciech Wojakowski et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Transplantation of Bone Marrow-Derived Very Small Embryonic-Like Stem Cells Attenuates Left Ventricular Dysfunction and Remodeling After Myocardial Infarction

(2008) Buddhadeb Dawn et al.   STEM CELLS