Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling

Strategies for rapidly mapping proviral integration sites and assessing cardiogenic potential of nascent human induced pluripotent stem cell clones

(2014) Cheryl Dambrot et al.   EXPERIMENTAL CELL RESEARCH

Excision of viral reprogramming cassettes by Cre protein transduction enables rapid, robust and efficient derivation of transgene-free human induced pluripotent stem cells

(2014) Asifiqbal Kadari et al.   Stem Cell Research & Therapy

Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions

(2013) Nan Cao et al.   CELL RESEARCH

Distinct iPS Cells Show Different Cardiac Differentiation Efficiency

(2013) Yohei Ohno et al.   Stem Cells International

Production of De Novo Cardiomyocytes: Human Pluripotent Stem Cell Differentiation and Direct Reprogramming

(2012) Paul W. Burridge et al.   Cell Stem Cell

Distinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes

(2012) Shugo Tohyama et al.   Cell Stem Cell

Perspectives on Stem Cell Therapy for Cardiac Regeneration

(2012) Sung Hyun Choi et al.   CIRCULATION JOURNAL

Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes

(2012) Christine L. Mummery et al.   CIRCULATION RESEARCH

Cozzarelli Prize Winner: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

(2012) X. Lian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stage-Specific Cardiomyocyte Differentiation Method for H7 and H9 Human Embryonic Stem Cells

(2012) Silin Sa et al.   Stem Cell Reviews and Reports

Cardiac Stem Cells and their Roles in Myocardial Infarction

(2012) Jingying Hou et al.   Stem Cell Reviews and Reports

Insulin Inhibits Cardiac Mesoderm, Not Mesendoderm, Formation During Cardiac Differentiation of Human Pluripotent Stem Cells and Modulation of Canonical Wnt Signaling Can Rescue This Inhibition

(2012) Xiaojun Lian et al.   STEM CELLS

A Small Molecule that Promotes Cardiac Differentiation of Human Pluripotent Stem Cells under Defined, Cytokine- and Xeno-free Conditions

(2012) Itsunari Minami et al.   Cell Reports

Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells

(2011) Nan Cao et al.   CELL RESEARCH

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

(2011) Steven J. Kattman et al.   Cell Stem Cell

Cardiomyocytes Obtained From Induced Pluripotent Stem Cells With Long-QT Syndrome 3 Recapitulate Typical Disease-Specific Features In Vitro

(2011) Daniela Malan et al.   CIRCULATION RESEARCH

Small molecule Wnt inhibitors enhance the efficiency of BMP-4-directed cardiac differentiation of human pluripotent stem cells

(2011) Yongming Ren et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Heart regeneration

(2011) Michael A. Laflamme et al.   NATURE

Efficient and Scalable Purification of Cardiomyocytes from Human Embryonic and Induced Pluripotent Stem Cells by VCAM1 Surface Expression

(2011) Hideki Uosaki et al.   PLoS One

Rat Embryonic Fibroblasts Improve Reprogramming of Human Keratinocytes into Induced Pluripotent Stem Cells

(2011) Leonhard Linta et al.   STEM CELLS AND DEVELOPMENT

Efficient Differentiation of Human Induced Pluripotent Stem Cells Generates Cardiac Cells That Provide Protection Following Myocardial Infarction in the Rat

(2011) Lee Carpenter et al.   STEM CELLS AND DEVELOPMENT

Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice

(2010) Shinji Kaichi et al.   CARDIOVASCULAR RESEARCH

Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals

(2010) Qiangzhe Zhang et al.   CELL RESEARCH

Cardiomyogenic Potential of C-Kit + –Expressing Cells Derived From Neonatal and Adult Mouse Hearts

(2010) Marc-Michael Zaruba et al.   CIRCULATION

Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway

(2010) Christophe Fuerer et al.   PLoS One

Bone morphogenetic protein-4 promotes induction of cardiomyocytes from human embryonic stem cells in serum-based embryoid body development

(2009) Shunsuke Takei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Transgenic simulation of human heart failure-like L-type Ca2+-channels: implications for fibrosis and heart rate in mice

(2009) Nadine Beetz et al.   CARDIOVASCULAR RESEARCH

Inactivation of L-type calcium channels is determined by the length of the N terminus of mutant β1 subunits

(2009) Wanchana Jangsangthong et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development

(2008) Charles E. Murry et al.   CELL

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

(2008) Lei Yang et al.   NATURE

Marked differences in differentiation propensity among human embryonic stem cell lines

(2008) Kenji Osafune et al.   NATURE BIOTECHNOLOGY