Review
Spectroscopy
Vladimir A. Azov, Larissa Mueller, Alexander A. Makarov
Summary: This review provides an overview of laser ionization mass spectrometry (LIMS), including the process of laser ionization, the influence of laser type on performance, and imaging capabilities. It also discusses the historic development of LIMS instrumentation, including first-generation instruments from the 1960-1990s and more recent designs. Additionally, it covers the recent applications of LIMS for surface analysis, including various analyses of solid inorganic, organic, and heterogeneous samples, often in combination with depth profiling and imaging capability.
MASS SPECTROMETRY REVIEWS
(2022)
Article
Spectroscopy
Yifan Meng, Le Hang, Wei Hang
Summary: Direct quantitative multi-elemental analysis of kelp was conducted using a high irradiance laser ionization time-of-flight mass spectrometer (LI-TOFMS), with low detection limits and high accuracy, suitable for kelp samples from different sea areas.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Ana Jerse, Kristina Mervic, Johannes Teun van Elteren, Vid Simon Selih, Martin Sala
Summary: Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has made significant improvements in reducing analysis time, increasing spatial resolution, and improving sensitivity. However, quantification and accurate analysis remain challenging. This study focuses on the influence of laser fluence, beam size, and aerosol transport on quantification in single pulse LA-ICP-MS analysis. The findings suggest that the right selection of laser fluence and beam size is critical for reliable quantification.
Article
Chemistry, Analytical
Noor Hidayat Abu Bakar, Kai-Chiang Yu, Pawel L. Urban
Summary: The study introduces a robotized pen-shaped probe called PENVOC for open-space sampling and mapping of VOCs emanating from solid specimens. The VOCs are sampled from the sample surface by a gentle hydrodynamic flow of air sustained by a vacuum pump and transferred to a tandem mass spectrometer for analysis. The technique may find applications in environmental, forensic, and food science.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Sabrina K. I. Funke, Valerie A. Brueckel, Markus Weber, Elias Luetzen, Jan-Christoph Wolf, Christoph Haisch, Uwe Karst
Summary: The combination of UV-laser ablation and mass spectrometry using DBDI allows for molecule-specific and spatially resolved analysis of solid samples without extensive preparation. The fast washout UV-laser ablation and the unique geometry of the DBDI source enable highly efficient soft ionization and high spatial resolution down to 10 mm for molecular imaging.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Marjan Dolatmoradi, Sylwia A. Stopka, Chloe Corning, Gary Stacey, Akos Vertes
Summary: In this study, a mass spectrometry enhanced with ion mobility separation and coupled with an automated sampling platform was utilized for in situ high-throughput single-cell metabolomics in soybean root nodules. The system achieved a high sampling rate and improved molecular coverage, leading to the discovery of metabolic heterogeneity. The upgraded platform allowed for the characterization of both unimodal and bimodal metabolite abundance distributions, revealing the presence of distinct subpopulations.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Thibaut Van Acker, Ana Rua-Ibarz, Frank Vanhaecke, Eduardo Bolea-Fernandez
Summary: In this study, laser ablation was investigated as a method for introducing microplastic particles into an inductively coupled plasma for monitoring using a mass spectrometer. Different types and sizes of microplastic particles were successfully introduced intact. The laser energy density did not affect particle sampling, and better performance was observed with a smaller laser beam diameter and a higher repetition rate. The C-13(+) signal intensity showed a linear correlation with the absolute carbon mass, and the linear range could be extended by using helium. Laser ablation generated narrower signal distributions compared to the traditional solution-based approach and was successful for analyzing mixed suspensions and sampling microplastic particles from filters.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yun-Nam Chan, Judy Tsz-Shan Lum, Kelvin Sze-Yin Leung
Summary: Hair and nails are increasingly being used in human biomonitoring due to their non-invasive sampling, stability, and ease of storage. However, the lack of standardized analytical protocols has hindered the use of laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) for elemental analysis of these samples. In this study, analytical methods were developed for the analysis of model elements in hair and nails using LA-ICP-MS. Critical aspects of the method, such as line scan vs. spot scan and sample cleaning, were evaluated. The study demonstrates the potential application of LA-ICP-MS in high throughput elemental analysis of hair and nail samples for future biomonitoring studies.
MICROCHEMICAL JOURNAL
(2023)
Review
Spectroscopy
Sarah Trimpin
Summary: This tutorial provides a summary of parameters for successful laserspray ionization (LSI) and related methods that use a laser to produce highly charged ions by ablating a matrix:analyte sample. The laser's purpose is to transfer matrix:analyte clusters into the gas phase. Ions are believed to be generated through a thermal process where charged particles/clusters of emitted matrix:analyte in the gas phase release the analyte ions after losing the matrix. The thermal energy responsible for the charge-separation process can be supplied by a heated inlet tube, which becomes the ion source, connecting atmospheric pressure to the first vacuum stage of a mass spectrometer. Parameters such as pressure, temperature, and the nature of the matrix (solid, liquid, or combinations) become critical factors. Injecting matrix:analyte into the heated inlet tube using laser ablation, shockwave, or tapping all yield similar mass spectra. Applications showcasing new opportunities in mass spectrometry are provided.
MASS SPECTROMETRY REVIEWS
(2023)
Article
Multidisciplinary Sciences
Sahar Sheta, Zongyu Hou, Yun Wang, Zhe Wang
Summary: The development of femtosecond laser induced breakdown spectroscopy (fs-LIBS) applications in the past two decades has focused on innovative techniques that combine the advantageous properties of femtosecond laser ablation (fs-LA) with LIBS. Despite the lack of research on the analytical capabilities of fs-LA in coal analysis, there is a growing need for fast and accurate analysis in the coal market. The evaluation of a one-box femtosecond laser system in comparison to an industrially applied coal analyzer has shown competitive results, paving the way for next-generation coal analyzers.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Analytical
Peng Yang, Rongxing Zhou, Jing Hu, Lijie Du, Feng Li, Junbo Chen, Xiandeng Hou
Summary: In this study, a lanthanide encoded logically gated micromachine (LGM-Ln) was constructed using a proximity assay, which can respond to multiple inputs in biological samples. The computational process of this system does not involve strand displacement, and a threshold-free design is employed to generate reliable computation values. By altering the affinity ligands, the LGM-Ln can be extended to sense nucleic acids and proteins in a multi-input mode.
ANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
L. Torrisi, M. Cutroneo, L. Silipigni, A. Torrisi
Summary: During the laser ablation of graphene oxide target, the plasma characterization has been obtained, revealing the ion species and charge states, as well as the average temperature and density. The ablation yield and the emitted mass yields increase with the laser fluence, along with elevated plasma density, temperature, and velocity of emitted particles. Laser heating results in reduction of graphene oxide and emission of oxygen in elemental and functional group forms, indicating the presence of water and hydrogen in the graphene oxide.
Article
Multidisciplinary Sciences
Dalia E. Ali, Samar M. Bassam, Soha Elatrebi, Esraa S. Habiba, Eman A. Allam, Eman M. Omar, Doaa A. Ghareeb, Shaymaa A. Abdulmalek, Essam Abdel-Sattar
Summary: The study investigated the protective effect of Yucca fruit extract on Parkinson's disease (PD) and found that it has a possible neuroprotective effect. The anti-inflammatory activity of Yucca fruit extracts was explored and the most effective extract was chosen. In vivo investigation on rats confirmed the effectiveness of the extract in improving neurobehavioral and locomotor activities, as well as renal and liver functions. The study suggests Yucca fruit as a promising therapeutic target for PD.
Article
Chemistry, Analytical
Zelin Liu, Guomin Zhao, Chuan Guo, Lei Chen, Minsun Chen, Hao Liu, Kai Han
Summary: This article presents an analytical method to validate local thermodynamic equilibrium in laser-induced plasmas, using a more universal function than the Maxwellian electron energy distribution function. The method estimates the evolution of the thermodynamic state in plasma by analyzing the actual EEDF of electrons at different positions. The consistency of similar EEDFs derived from emission lines associated with differently charged ions justifies the method as a reasonable LTE criterion.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2021)
Article
Chemistry, Analytical
Frederic Fournelle, Nidia Lauzon, Ethan Yang, Pierre Chaurand
Summary: Traditionally, MALDI IMS requires the deposition of an organic matrix, which often generates high background noise in the low mass range. LDI offers selective ionization with low background in the low mass range. This article discusses the advantages and disadvantages of solvent free and wet deposition of metals as LDI matrices and demonstrates the power of metal-assisted LDI for analyzing low molecular weight molecules in tissue sections.
MICROCHEMICAL JOURNAL
(2023)
Article
Engineering, Environmental
Jikang Li, Qin Yang, Sheng Chen, Kerry McPhedran, Yingchun Gu, Rongfu Huang, Bin Yan
Summary: In this study, a hierarchically porous crosslinked polymeric microbead (PCP) with high density of functional groups was designed and fabricated for selective adsorption of cationic dyes from water. The PCP showed high efficiency in removing cationic dyes and exhibited high recyclability. The integration of a closed-loop recycling system effectively addressed the issue of secondary effluent in wastewater treatment processes.
ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY
(2022)
Review
Engineering, Environmental
Chunxiu Yu, Zhaokun Xiong, Hongyu Zhou, Peng Zhou, Heng Zhang, Rongfu Huang, Gang Yao, Bo Lai
Summary: The integration of membrane filtration (MF) and sulfate radical-advanced oxidation processes (SR-AOPs) has gained extensive attention in environmental remediation for its simultaneous degradation and filtration of pollutants in wastewater. This review comprehensively summarizes the classification, preparation methods, and properties of different types of membrane-based materials and filtration devices, as well as the mechanisms, technical challenges, and prospects of the collaborative mixing process.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Cell Biology
Jianfeng Yao, Ming Li, Liqing Lin, Youzhu Li, Jianlong Zhuang, Yanfang Huang, Weilin Peng, Jianfeng Lian, Rongfu Huang, Xiaoyu Yang
Summary: This study analyzes the expression level of the PTEN gene in human cumulus cells and explores its association with embryo developmental competence. The study finds that the expression level of PTEN is significantly decreased in cumulus cells surrounding mature oocytes, and this change is also related to fertilization and blastocyst formation.
Article
Genetics & Heredity
Jianlong Zhuang, Chunnuan Chen, Rongfu Huang, Qi Luo, Yuying Jiang, Shuhong Zeng, Yuanbai Wang, Yingjun Xie
Summary: This study presents the first case of partial 10p monosomy associated with 10q trisomy in the Chinese population, further strengthening the application value of microarray in the molecular etiological diagnosis of recurrent spontaneous abortion.
MOLECULAR CYTOGENETICS
(2022)
Article
Engineering, Environmental
Yu Chen, Xianhu Long, Rongfu Huang, Igor Ying Zhang, Gang Yao, Bo Lai, Zhaokun Xiong
Summary: In this study, an electrochemical/peroxymonosulfate/Fe(III) system was established for efficient degradation of four naphthenic acids (NAs) compounds. The primary reactive oxygen species (ROS) in this system were identified as hydroxyl radical, sulfate radical, and singlet oxygen. The degradation efficiency of different NAs compounds varied depending on the selectivity of ROS and stability of intermediate organic radicals. Additionally, the system showed robust performance in the presence of co-existing ions.
CHEMICAL ENGINEERING JOURNAL
(2022)
Review
Environmental Sciences
Xi Yu, Kerry Neil McPhedran, Rongfu Huang
Summary: Chlorinated paraffins (CPs) are released into the environment during production and utilization, with diet being the main exposure route for humans. Short-chain CPs (SCCPs) are more likely to be released because of their lower molecular weights, higher vapor pressures, and higher water solubilities compared to medium-chain (MCCPs) and long-chain (LCCPs) CPs. This review article discusses sample preparation and instrumental analysis methods for CPs in different types of food, such as oil, meat, and aquatic foods. It also summarizes concentrations, profiles, dietary intake, and risk assessment of CPs in food samples from various regions, highlighting the need for continuous monitoring and awareness of the potential health risks associated with increasing CPs concentrations in food worldwide.
ENVIRONMENTAL POLLUTION
(2023)
Article
Engineering, Environmental
Yuchen Zhang, Peng Zhou, Rongfu Huang, Chenying Zhou, Yang Liu, Heng Zhang, Xiaowei Huo, Jian Zhao, Zhaokun Xiong, Bo Lai
Summary: In this study, iron boride (FeB) was proposed as a new material to sustainably decompose H2O2 to generate hydroxyl radicals, which can degrade refractory organic pollutants. Fe(II) was steadily released by the oxidation of FeB, and B-B bonds on the surface of FeB promoted the regeneration of Fe(II) from Fe(III) and accelerated the production of hydroxyl radicals. The FeB/H2O2 system showed low generation of toxic by-products and high utilization rate of iron species, providing a green and long-lasting environmental remediation strategy.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Food Science & Technology
Xiaofang Jiang, Kerry Neil McPhedran, Xiandeng Hou, Yu Chen, Rongfu Huang
Summary: This study investigated the potential impacts of trace-level metals on the taste and flavour of a traditional rice-based product called Grape Well rice cake. The results showed that elevated concentrations of Sr and Ba were found in Grape Well water samples, which contributed significantly to distinguishing Grape Well rice cake from Chengdu rice cake. The different taste of these two rice cakes is likely due to distinct concentrations of metals, such as Sr and Ba. Overall, this study highlights the importance of developing quality control criteria for the manufacturing of traditionally crafted rice cake.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Geography, Physical
Tao Zhan, Ye Yang, Yanxia Liang, Xiaoyan Liu, Fangming Zeng, Junyi Ge, Yongfa Ma, Keliang Zhao, Xinying Zhou, Xia Jiang, Rongfu Huang, Xun Wang, Xin Zhou, Chenglong Deng
Summary: The Mid-Pleistocene transition (MPT) was characterized by changes in ice volume periodicities, high latitude ice sheets, global sea level, and CO2 / ocean carbon storage, which influenced the evolution of the East Asian summer monsoon (EASM). Pollen analysis of lacustrine sediments revealed a vegetation succession from a semi-humid to a semi-arid climate during the MPT. Palynological records from various regions also indicated a drying climate, related to the decreasing trend of EASM precipitation. The reduction in EASM precipitation during the MPT was mainly caused by falling global sea level, exposure of continental shelves, increased transport distance of oceanic water vapor, and potential weakening of oceanic circulations.
PALAEOGEOGRAPHY PALAEOCLIMATOLOGY PALAEOECOLOGY
(2023)
Article
Chemistry, Analytical
Shaoyang Yu, Yating Yang, Gaoya Hu, Wei Wang, Wei Zhuang, Yong Wu, Rongfu Huang, Yongquan Zhang, Sisi Gong, Chunmei Fan
Summary: A novel fluorescence and colorimetric dual probe based on the inner filter effect (IFE) was developed for the selective and sensitive determination of alkaline phosphatase (ALP). The probe utilized up-conversion nanoparticles (UCNPs) and p-phenylenediamine (PPD) as the fluorophore and quencher, respectively. The fluorescence of UCNPs was restored by the reaction of ALP and ascorbic acid 2-phosphate (AAP). The assay demonstrated high sensitivity and accuracy for ALP determination.
ANALYTICAL LETTERS
(2023)
Article
Engineering, Environmental
Xianhu Long, Hongle Shi, Rongfu Huang, Lingyun Gu, Yang Liu, Chuan-shu He, Ye Du, Zhaokun Xiong, Wen Liu, Bo Lai
Summary: In this study, sustainable Fe(III)/Fe(II) cycles in different inorganic peroxides activation systems were accelerated by using electro-catalysis (EC) as the electron donor. The electro-cocatalytic Fenton-like systems exhibited excellent degradation efficiency of sulfamethoxazole (SMX). Various reactive oxygen species (ROS) including hydroxyl radical ((OH)-O-center dot), singlet oxygen (O-1(2)), and sulfate radical (SO4 center dot-) were produced in EC/Fe(III)/PMS system, contributing to 38%, 37%, and 24% respectively. The dominant ROS in EC/Fe(III)/ PDS and EC/Fe(III)/HP processes was (OH)-O-center dot. The study provides a strong basis for constructing suitable systems to achieve different treatment requirements.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Immunology
Jinqing Lai, Genwang Chen, Zhe Wu, Shaoyang Yu, Rongfu Huang, Yile Zeng, Weibin Lin, Chunmei Fan, Xiangrong Chen
Summary: PHLDA1 plays a crucial role in the immune response after SAH by balancing microglia M1/M2 polarization and suppressing NLRP3 inflammasome signaling, which reduces neuroinflammation, neuronal apoptosis, and improves neurological outcomes.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Geochemistry & Geophysics
Zhan Tao, Yang Ye, Zeng FangMing, Liang YanXia, Ge JunYi, Ma YongFa, Kong XiangHui, Zhang Li, Xia Jiang, Huang RongFu, Wang Xun, Zhou Xin
Summary: Lacustrine sediments in the Northeast China Plain provide valuable information for studying the evolution of climate and environment. Through geochronology and rock magnetism analysis of a borehole in Dumeng county, it was found that the shrinkage of the Songnen paleo-lake around 900 ka could be attributed to the decrease in East Asian summer monsoon precipitation. The weakening of the Atlantic meridional overturning circulation and the southward movement of the Intertropical Convergence Zone in the tropical Pacific were likely the main causes for the reduction in monsoon precipitation.
CHINESE JOURNAL OF GEOPHYSICS-CHINESE EDITION
(2023)
Review
Oncology
Gen-Wang Chen, Mei-Na Chen, Lei Liu, Yu-Yu Zheng, Jin-Peng Wang, Si-Si Gong, Rong-Fu Huang, Chun-Mei Fan, Yue-Zu Chen
Summary: This paper reviews the research status of animal models in Myelodysplastic syndrome (MDS), which have significant value in simulating human genetic variations and disease characteristics.
CLINICAL & TRANSLATIONAL ONCOLOGY
(2023)
Article
Chemistry, Analytical
Yuyu Zheng, Jinpeng Wang, Genwang Chen, Meie Wang, Tebin Chen, Qiaohong Ke, Yajun Huang, Fan Cai, Rongfu Huang, Chunmei Fan
Summary: An innovative and simple electrochemical aptasensing platform was designed for the voltammetric detection of prostate-specific antigen (PSA) in biological fluids. The method showed good sensitivity and reproducibility, and yielded consistent results compared to the traditional enzyme-linked immunosorbant assay (ELISA) method. This technique provides a new possibility for the quantitative monitoring of low-concentration biomarkers or nucleic acids.
Article
Spectroscopy
Piyali Deb Barman, Ashok Kumar Maurya, Subhendu Ghosh, Ankit Roy, Mukul Madaan
Summary: In X-ray spectroscopic studies, K beta 1,3 lines have been used to examine the chemical states of 3d transition metals, but are not suitable for characterizing iron oxides. Instead, FeL-lines, which involve the valence shell 3d electrons, were inspected and found to provide information on the chemical states of iron. The study established a linear relationship between the chemical shift of FeL beta 1 line and spin multiplicity, allowing for the speciation of iron.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2024)
