Vitamins in Pancreatic Cancer: A Review of Underlying Mechanisms and Future Applications

The vitamin D analog, MART-10, represses metastasis potential via downregulation of epithelial–mesenchymal transition in pancreatic cancer cells

(2014) Kun-Chun Chiang et al.   CANCER LETTERS

Vitamin K2 Therapy for Postmenopausal Osteoporosis

(2014) Jun Iwamoto   Nutrients

Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial

(2013) J. L. Welsh et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Retinoic acid inhibits pancreatic cancer cell migration and EMT through the downregulation of IL-6 in cancer associated fibroblast cells

(2013) Jian Guan et al.   CANCER LETTERS

Vitamin E  -Tocotrienol Prolongs Survival in the LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) Transgenic Mouse Model of Pancreatic Cancer

(2013) K. Husain et al.   Cancer Prevention Research

Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E  -tocotrienol

(2013) K. Husain et al.   CARCINOGENESIS

Evaluation of the potential therapeutic role of a new generation of vitamin D analog, MART-10, in human pancreatic cancer cells in vitro and in vivo

(2013) Kun-Chun Chiang et al.   CELL CYCLE

Tumor–stromal interactions in breast tumor progression – significance of histological heterogeneity of tumor–stromal fibroblasts

(2013) Takahiro Hasebe   EXPERT OPINION ON THERAPEUTIC TARGETS

Retinoids and their biological effects against cancer

(2013) Fatemeh Alizadeh et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Molecular communication between tumor-associated fibroblasts and head and neck squamous cell carcinoma

(2013) George Leef et al.   ORAL ONCOLOGY

Vitamin E δ-Tocotrienol Induces p27Kip1-Dependent Cell-Cycle Arrest in Pancreatic Cancer Cells via an E2F-1-Dependent Mechanism

(2013) Pamela J. Hodul et al.   PLoS One

Genetic Variants in Vitamin D Pathway Genes and Risk of Pancreas Cancer; Results from a Population-Based Case-Control Study in Ontario, Canada

(2013) Laura N. Anderson et al.   PLoS One

mTOR plays critical roles in pancreatic cancer stem cells through specific and stemness-related functions

(2013) Shyuichiro Matsubara et al.   Scientific Reports

Nutrition and physical activity guidelines for cancer survivors

(2012) Cheryl L. Rock et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Stromal cells in tumor microenvironment and breast cancer

(2012) Yan Mao et al.   CANCER AND METASTASIS REVIEWS

Plasma 25-Hydroxyvitamin D and Risk of Pancreatic Cancer

(2012) B. M. Wolpin et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Abstract 1299: A phase I dose-escalation study of the safety, PK, and PD of vitamin E Δ-tocotrienol administered to subjects with resectable pancreatic exocrine neoplasia

(2012) Gregory M. Springett et al.   CANCER RESEARCH

Retinoic acid suppresses growth of lesions, inhibits peritoneal cytokine secretion, and promotes macrophage differentiation in an immunocompetent mouse model of endometriosis

(2012) Friedrich Wieser et al.   FERTILITY AND STERILITY

Cancer-Associated Fibroblasts Drive the Progression of Metastasis through both Paracrine and Mechanical Pressure on Cancer Tissue

(2012) G. S. Karagiannis et al.   MOLECULAR CANCER RESEARCH

Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer

(2012) Daniel A. Monti et al.   PLoS One

Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours

(2011) R Pili et al.   BRITISH JOURNAL OF CANCER

Tocotrienols inhibit AKT and ERK activation and suppress pancreatic cancer cell proliferation by suppressing the ErbB2 pathway

(2011) Sonyo Shin-Kang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer

(2011) Michael Graham Espey et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells

(2011) Dorrelyn Patacsil et al.   Genes and Nutrition

Vitamin E  -Tocotrienol Augments the Antitumor Activity of Gemcitabine and Suppresses Constitutive NF- B Activation in Pancreatic Cancer

(2011) K. Husain et al.   MOLECULAR CANCER THERAPEUTICS

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

(2011) Thierry Conroy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of target gene expression by the vitamin D receptor - an update on mechanisms

(2011) J. Wesley Pike et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Vitamin D and Pancreatic Cancer—An Update

(2011) Kun-Chun Chiang et al.   Cancers

Circulating 25-Hydroxyvitamin D and Risk of Pancreatic Cancer: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers

(2010) R. Z. Stolzenberg-Solomon et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

 -Tocotrienol Inhibits Pancreatic Tumors and Sensitizes Them to Gemcitabine Treatment by Modulating the Inflammatory Microenvironment

(2010) A. B. Kunnumakkara et al.   CANCER RESEARCH

Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

(2010) J. Du et al.   CLINICAL CANCER RESEARCH

In vitro effect of granulocyte-colony stimulating factor and all-trans retinoic acid on the expression of inflammatory cytokines and adhesion molecules in acute promyelocytic leukemic cells

(2010) Hui-Chi Hsu et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Role of Vitamin and Mineral Supplementation and Aspirin Use in Cancer Survivors

(2010) Edward Giovannucci et al.   JOURNAL OF CLINICAL ONCOLOGY

Inflammatory cytokine release of astrocytes in vitro is reduced by all-trans retinoic acid

(2010) Sabien van Neerven et al.   JOURNAL OF NEUROIMMUNOLOGY

Analogs of Vitamin E Epitomized by α-Tocopheryl Succinate for Pancreatic Cancer Treatment

(2010) Eliana Greco et al.   PANCREAS

Downregulation of nuclear factor-κB p65 subunit by small interfering RNA synergizes with gemcitabine to inhibit the growth of pancreatic cancer

(2009) Rui Kong et al.   CANCER LETTERS

IKK/NF-κB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis

(2009) Julia Bollrath et al.   EMBO REPORTS

Long-Term Results for Children With High-Risk Neuroblastoma Treated on a Randomized Trial of Myeloablative Therapy Followed by 13-cis-Retinoic Acid: A Children's Oncology Group Study

(2009) Katherine K. Matthay et al.   JOURNAL OF CLINICAL ONCOLOGY

Involvement of hepatoma-derived growth factor in the growth inhibition of hepatocellular carcinoma cells by vitamin K2

(2009) Teruhisa Yamamoto et al.   JOURNAL OF GASTROENTEROLOGY

Naturally occurring K vitamins inhibit pancreatic cancer cell survival through a caspase-dependent pathway

(2009) Shayna L Showalter et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Inhibition of proliferation and induction of apoptosis by γ-tocotrienol in human colon carcinoma HT-29 cells

(2009) Wei-Li Xu et al.   NUTRITION

Chemoradioimmunotherapy in Locally Advanced Pancreatic and Biliary Tree Adenocarcinoma

(2009) Francesco Recchia et al.   PANCREAS

d-δ-Tocotrienol-Mediated Suppression of the Proliferation of Human PANC-1, MIA PaCa-2, and BxPC-3 Pancreatic Carcinoma Cells

(2009) Deema Hussein et al.   PANCREAS

Vitamin E δ-Tocotrienol Levels in Tumor and Pancreatic Tissue of Mice after Oral Administration

(2009) Kazim Husain et al.   PHARMACOLOGY

Vitamin D for the prevention and treatment of pancreatic cancer

(2009) Kun-Chun Chiang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Nuclear Factor- B p65/relA Silencing Induces Apoptosis and Increases Gemcitabine Effectiveness in a Subset of Pancreatic Cancer Cells

(2008) X. Pan et al.   CLINICAL CANCER RESEARCH

Phase II study of calcitriol-enhanced docetaxel in patients with previously untreated metastatic or locally advanced pancreatic cancer

(2008) C. D. Blanke et al.   INVESTIGATIONAL NEW DRUGS

Vitamin and Mineral Supplement Use Among US Adults After Cancer Diagnosis: A Systematic Review

(2008) Christine M. Velicer et al.   JOURNAL OF CLINICAL ONCOLOGY

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

(2008) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis

(2008) R. Brooks Robey et al.   SEMINARS IN CANCER BIOLOGY