Secreted aspartic proteases ofCandida albicansactivate the NLRP3 inflammasome

Pannexin-1-Mediated Intracellular Delivery of Muramyl Dipeptide Induces Caspase-1 Activation via Cryopyrin/NLRP3 Independently of Nod2

(2014) N. Marina-Garcia et al.   JOURNAL OF IMMUNOLOGY

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis

(2011) Frank L. van de Veerdonk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A highly immunogenic recombinant and truncated protein of the secreted aspartic proteases family (rSap2t) ofCandida albicansas a mucosal anticandidal vaccine

(2011) Silvia Sandini et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Escherichia coli Heat-Labile Enterotoxin Promotes Protective Th17 Responses against Infection by Driving Innate IL-1 and IL-23 Production

(2011) C. F. Brereton et al.   JOURNAL OF IMMUNOLOGY

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

(2011) Shih-Chin Cheng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Inflammasome activation and IL-1β and IL-18 processing during infection

(2011) Frank L. van de Veerdonk et al.   TRENDS IN IMMUNOLOGY

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes

(2010) C Oberle et al.   CELL DEATH AND DIFFERENTIATION

The role of inflammasomes in the immunostimulatory effects of particulate vaccine adjuvants

(2010) James Harris et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Inflammatory Response Induced by Aspartic Proteases of Candida albicans Is Independent of Proteolytic Activity

(2010) D. Pietrella et al.   INFECTION AND IMMUNITY

Molecular Mechanism of NLRP3 Inflammasome Activation

(2010) Chengcheng Jin et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Inflammasome Activation by Adenylate Cyclase Toxin Directs Th17 Responses and Protection against Bordetella pertussis

(2010) A. Dunne et al.   JOURNAL OF IMMUNOLOGY

Aspergillus fumigatus Stimulates the NLRP3 Inflammasome through a Pathway Requiring ROS Production and the Syk Tyrosine Kinase

(2010) Najwane Saïd-Sadier et al.   PLoS One

Autophagy: a broad role in unconventional protein secretion?

(2010) Ravi Manjithaya et al.   TRENDS IN CELL BIOLOGY

Fungal pathogen recognition by the NLRP3 inflammasome

(2010) Sophie Joly et al.   Virulence

Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4

(2010) Edel A. McNeela et al.   PLoS Pathogens

Mechanisms of interleukin-1β release

(2009) Claudia Eder   IMMUNOBIOLOGY

Inflammasome-dependent Caspase-1 Activation in Cervical Epithelial Cells Stimulates Growth of the Intracellular PathogenChlamydia trachomatis

(2009) Ali A. Abdul-Sater et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathogen-Induced Interleukin-1  Processing and Secretion Is Regulated by a Biphasic Redox Response

(2009) S. Tassi et al.   JOURNAL OF IMMUNOLOGY

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

The NLRP3 inflammasome: A sensor of immune danger signals

(2009) Suzanne L. Cassel et al.   SEMINARS IN IMMUNOLOGY

Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases

(2009) Marina Tiemi Shio et al.   PLoS Pathogens

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD

The Cytosolic Sensors Nod1 and Nod2 Are Critical for Bacterial Recognition and Host Defense after Exposure to Toll-like Receptor Ligands

(2008) Yun-Gi Kim et al.   IMMUNITY

A Candida albicans Mannoprotein Deprived of Its Mannan Moiety Is Efficiently Taken Up and Processed by Human Dendritic Cells and Induces T-Cell Activation without Stimulating Proinflammatory Cytokine Production

(2008) D. Pietrella et al.   INFECTION AND IMMUNITY

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1  and IL-18 secretion in an autocrine way

(2008) A. Piccini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ameobal Pathogen Mimivirus Infects Macrophages through Phagocytosis

(2008) Eric Ghigo et al.   PLoS Pathogens