PD-1 Blockade for Improving the Antitumor Efficiency of Polymer-Doxorubicin Nanoprodrug

Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade

(2018) Shuangjiang Yu et al.   ADVANCED MATERIALS

In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

(2018) Chao Wang et al.   Science Translational Medicine

Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer

(2018) Jutaek Nam et al.   Nature Communications

Receptor and Microenvironment Dual-Recognizable Nanogel for Targeted Chemotherapy of Highly Metastatic Malignancy

(2017) Jinjin Chen et al.   NANO LETTERS

Acidity-Triggered Tumor-Targeted Chimeric Peptide for Enhanced Intra-Nuclear Photodynamic Therapy

(2016) Kai Han et al.   ADVANCED FUNCTIONAL MATERIALS

Inflammation-Triggered Cancer Immunotherapy by Programmed Delivery of CpG and Anti-PD1 Antibody

(2016) Chao Wang et al.   ADVANCED MATERIALS

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

(2016) Jianjun Gao et al.   CELL

Tumor-Triggered Drug Release with Tumor-Targeted Accumulation and Elevated Drug Retention To Overcome Multidrug Resistance

(2016) Wei-Hai Chen et al.   CHEMISTRY OF MATERIALS

New insights and evolving role of pegylated liposomal doxorubicin in cancer therapy

(2016) Alberto A. Gabizon et al.   DRUG RESISTANCE UPDATES

Oligo(lactic acid)n-Paclitaxel Prodrugs for Poly(ethylene glycol)-block-poly(lactic acid) Micelles: Loading, Release, and Backbiting Conversion for Anticancer Activity

(2016) Yu Tong Tam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Integrated Nano-Platform for Breaking the Barrier between Chemotherapy and Immunotherapy

(2016) Di-Wei Zheng et al.   NANO LETTERS

Preferential Cancer Cell Self-Recognition and Tumor Self-Targeting by Coating Nanoparticles with Homotypic Cancer Cell Membranes

(2016) Jing-Yi Zhu et al.   NANO LETTERS

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Tumor microenvironment sensitive doxorubicin delivery and release to glioma using angiopep-2 decorated gold nanoparticles

(2015) Shaobo Ruan et al.   BIOMATERIALS

Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

(2015) Padmanee Sharma et al.   CELL

Development of individualized anti-metastasis strategies by engineering nanomedicines

(2015) Qianjun He et al.   CHEMICAL SOCIETY REVIEWS

Using Hollow Carbon Nanospheres as a Light-Induced Free Radical Generator To Overcome Chemotherapy Resistance

(2015) Liming Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1

(2015) E. Vacchelli et al.   SCIENCE

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Bioinspired Nano-Prodrug with Enhanced Tumor Targeting and Increased Therapeutic Efficiency

(2015) Wei-Hai Chen et al.   Small

Body fat composition impacts the hematologic toxicities and pharmacokinetics of doxorubicin in Asian breast cancer patients

(2014) A. L. Wong et al.   BREAST CANCER RESEARCH AND TREATMENT

Consensus guidelines for the detection of immunogenic cell death

(2014) Oliver Kepp et al.   OncoImmunology

Spatiotemporal Drug Release Visualized through a Drug Delivery System with Tunable Aggregation-Induced Emission

(2013) Xiangdong Xue et al.   ADVANCED MATERIALS

MSN Anti-Cancer Nanomedicines: Chemotherapy Enhancement, Overcoming of Drug Resistance, and Metastasis Inhibition

(2013) Qianjun He et al.   ADVANCED MATERIALS

Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer

(2013) L Bracci et al.   CELL DEATH AND DIFFERENTIATION

Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells

(2013) Yuting Ma et al.   IMMUNITY

Tumor metastasis: moving new biological insights into the clinic

(2013) Liling Wan et al.   NATURE MEDICINE

Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

(2013) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recent trends in the design of anticancer polymer prodrug nanocarriers

(2013) Vianney Delplace et al.   Polymer Chemistry

Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells

(2013) S. Spranger et al.   Science Translational Medicine

Insight into aggregation-induced emission characteristics of red-emissive quinoline-malononitrile by cell tracking and real-time trypsin detection

(2013) Andong Shao et al.   Chemical Science

Why does cancer therapy lack effective anti-metastasis drugs?

(2012) Georg F. Weber   CANCER LETTERS

Real-time In Vivo Molecular Detection of Primary Tumors and Metastases with Ratiometric Activatable Cell-Penetrating Peptides

(2012) E. N. Savariar et al.   CANCER RESEARCH

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Doxorubicin Plus Sorafenib vs Doxorubicin Alone in Patients With Advanced Hepatocellular Carcinoma

(2010) Ghassan K. Abou-Alfa et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Pegylated Liposomal Doxorubicin and Carboplatin Compared With Paclitaxel and Carboplatin for Patients With Platinum-Sensitive Ovarian Cancer in Late Relapse

(2010) Eric Pujade-Lauraine et al.   JOURNAL OF CLINICAL ONCOLOGY

Doxorubicin pathways

(2010) Caroline F. Thorn et al.   Pharmacogenetics and Genomics

Prospective Randomized Study of Doxorubicin-Eluting-Bead Embolization in the Treatment of Hepatocellular Carcinoma: Results of the PRECISION V Study

(2009) Johannes Lammer et al.   CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY