Article
Multidisciplinary Sciences
Nichola J. Starr, Mohammed H. Khan, Max K. Edney, Gustavo F. Trindade, Stefanie Kern, Alexander Pirkl, Matthias Kleine-Boymann, Christopher Elms, Mark M. O'Mahony, Mike Bell, Morgan R. Alexander, David J. Scurr
Summary: In this study, the 3D OrbiSIMS technique was used to analyze the molecular chemistry of human skin tissue and provide unprecedented details about the nonhomogeneity of the stratum corneum. The analysis resolved debates about chemical gradients within the epidermis and revealed similarities in epidermal compounds between human and porcine skin. Additionally, the study demonstrated the permeation of an antiaging peptide into the human stratum corneum.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Pharmacology & Pharmacy
Ana Isabel Barbosa, Sofia A. Costa Lima, Ibraheem Yousef, Salette Reis
Summary: In this study, menthol, L-linalool, bergamot oil, and beta-pinene were incorporated in alginate/fucoidan hydrogels to evaluate their skin permeation enhancement profile and assess their influence on the skin organization. The study highlights the effect of the composition in the design of formulations for topical or transdermal delivery systems.
Article
Biochemistry & Molecular Biology
Adrienn Jenei, Gergo Kallo, Zsolt Dajnoki, Krisztian Gaspar, Andrea Szegedi, Aniko Kapitany, Eva Csosz
Summary: This study developed a novel approach for examining AMPs in the outer layer of the epidermis, with hexane-free processing producing higher protein yield. Among the investigated peptides, 9 could be detected in healthy or inflamed skin, and significant topographical differences were observed in the amount of certain peptides among different regions of healthy skin.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Applied
Chongshan Yang, Dandan Duan, Chunwang Dong, Chuanxia Li, Guanglin Li, Yunhai Zhou, Yifan Gu, Yachao Liu, Chunjiang Zhao, Daming Dong
Summary: Aroma is crucial in assessing tea quality. Illegal traders often add essence to expired or substandard tea to enhance its aroma for greater profit. Conventional testing methods are time-consuming and costly, while near-infrared spectroscopy and machine vision can only detect powdered solid essences in tea. In this study, proton-transfer reaction mass spectrometry (PTR-MS) and Fourier-transform infrared spectroscopy (FTIR) were used to rapidly detect volatile organic compounds (VOCs) in tea samples adulterated with liquid essence, achieving high prediction accuracies of 0.941 and 0.957, respectively. The study discusses the different application scenarios of the two technologies based on their performance characteristics.
Article
Biology
Dinesh Kumar, Pawan Kumar, Kumar Vikram, Himmat Singh
Summary: The study investigates the bio-efficacy of Pimenta dioica leaf derived silver nanoparticles (Pd@AgNPs) against malaria, filarial, and dengue vectors. The synthesized Pd@AgNPs showed larvicidal activity against the larvae of Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus without affecting non-targeted organisms. The green synthesis of AgNPs offers an effective technique for mosquito control and other therapeutic applications.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2022)
Article
Plant Sciences
Hayden E. Hodges, Heather J. Walker, Aaron J. Cowieson, Robert J. Falconer, Duncan D. Cameron
Summary: Modern feed quality sorghum grain has been bred to reduce anti-nutrients, but its inclusion in monogastric animal diets can still result in variable performance. Sorghum grain contains several negative intrinsic factors which may be responsible for muted feed performances. FT-IR and mass spectrometry can be used to discriminate among different sorghum varieties, and could be incorporated into quality control applications.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Madoka Suzuki, Yusuke Ohno, Akio Kihara
Summary: This study used LC/MS/MS analysis to identify 1,327 unbound ceramides and 254 protein-bound ceramides in the stratum corneum. The researchers discovered a wide variety of ceramide species with different long-chain bases in the human skin, and demonstrated the production of specific long-chain bases by one of the enzymes. This study provides a molecular basis for understanding ceramide diversity in the skin and the pathogenesis of skin disorders.
JOURNAL OF LIPID RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Madoka Suzuki, Yusuke Ohno, Akio Kihara
Summary: This study conducted LC/MS/MS analyses to reveal various ceramide species in the human stratum corneum, quantifying a large number of ceramides and providing a molecular basis for understanding the diversity of human skin ceramides and the pathogenesis of skin disorders.
JOURNAL OF LIPID RESEARCH
(2022)
Article
Polymer Science
Yilan Cai, Liling Jia, Hao Li, Yujie He, Yong Liu, Rui Jia, Dan Yang, Runtao Xia, Jingpeng Jiao, Ju Huang, Yun Weng, Jichao Zhang, Hailing Zheng, Hailiang Yang, Bing Wang, Yang Zhou, Zhiqin Peng
Summary: Understanding the degradation of silk fibers and tracing silk fabrics from archeological sites have always been challenging. This study examines Chinese historic silk fabrics from various dynasties as well as artificially aged silk specimens to investigate their degradation using techniques such as scanning electron microscopy, attenuated total reflection-Fourier transform infrared spectroscopy, and isotope ratio mass spectrometry. The results provide insights into the silk degradation mechanism and can be useful for tracing the rich textile heritage.
POLYMER DEGRADATION AND STABILITY
(2023)
Article
Optics
Jeremy Xuan Yu Chew, Zi Heng Lim, Y. Qi, Guangcan Zhou, Guangya Zhou
Summary: Infrared devices are increasingly used in various applications. This paper introduces a novel dispersive spectrometer that has high-throughput and decoupled spectral resolution. The proposed spectrometer utilizes a two-stage Hadamard transform encoding process to increase the signal-to-noise ratio. With a single-pixel detector, the system can be easily implemented in other desired wavelengths. Additionally, a method is developed to remove the need for uniform illumination and improve the ease of device design for in situ measurement.
Article
Microbiology
Sarunpron Khruengsai, Teerapong Sripahco, Patcharee Pripdeevech
Summary: This study investigates the biodegradation efficiency of polyester urethanes (PUR) by different fungal species and explores the degradation mechanism of Embarria clematidis. The results show that Embarria clematidis not only partially degrades PUR, but also mineralizes it into CO2 and H2O.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Multidisciplinary Sciences
Ruhul Amin, Anna Lechner, Annika Vogt, Ulrike Blume-Peytavi, Jan Kottner
Summary: A variety of molecules have been identified for quantifying xerosis cutis, but there is substantial heterogeneity in molecular marker selection, tissue sampling, and laboratory analyses. Despite associations of these markers with skin dryness, reports of unclear and/or no association are also common.
Article
Biochemical Research Methods
Jacob W. McCabe, Benjamin J. Jones, Thomas E. Walker, Robert L. Schrader, Adam P. Huntley, Jixing Lyu, Nathan M. Hoffman, Gordon A. Anderson, Peter T. A. Reilly, Arthur Laganowsky, Vicki H. Wysocki, David H. Russell
Summary: This study presents a digital-waveform dual-quadrupole mass spectrometer to improve the performance of a drift tube FT-IMS high-resolution Orbitrap mass spectrometer in studying large proteins and protein complexes. The dual-quadrupole analyzer allows for low-energy collisional activation of ions and precise mass selection using digital-waveform technology, enhancing the capabilities of the instrument at a lower cost compared to traditional RF drivers.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2021)
Article
Biochemical Research Methods
Elvin R. Cabrera, Brian H. Clowers
Summary: By casting ion population's mobility information in the frequency domain, time-dispersive ion mobility techniques can now be compatible with slower mass analyzers like ion traps. Recent progress has been made in maximizing the efficiency of Fourier transform ion mobility-mass spectrometry (FT-IM-MS) experiments, but the intersection between practical implementation considerations and theoretical limits of traditional signal processing techniques needs to be further explored. The importance of avoiding signal aliasing due to undersampling signals, along with evaluating limitations imposed by experimental parameters, is crucial for successful Fourier-based multiplexing experiments.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2022)
Review
Biochemical Research Methods
Sarah Macpherson, Kyle Duncan, David R. Goodlett, Julian J. Lum
Summary: Despite practical complexities, isotope tracing studies in humans are becoming increasingly feasible. Researchers propose an alternative liquid tumor environment and strategies for cell-type-specific analysis to overcome current limitations.
CURRENT OPINION IN BIOTECHNOLOGY
(2023)
