Elucidating the molecular landscape of the stratum corneum

Molecular Formula Prediction for Chemical Filtering of 3D OrbiSIMS Datasets

(2022) Max K. Edney et al.   ANALYTICAL CHEMISTRY

Skin permeability barrier formation by the ichthyosis-causative gene FATP4 through formation of the barrier lipid ω-O-acylceramide

(2020) Haruka Yamamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-OrbiSIMS for 3D molecular imaging of a bacterial biofilm in its native state

(2020) Junting Zhang et al.   ANALYTICAL CHEMISTRY

Cryogenic OrbiSIMS Localizes Semi‐Volatile Molecules in Biological Tissues

(2020) Clare L. Newell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Examination of beauty ingredient distribution in the human skin by time-of-flight secondary ion mass spectrometry

(2020) Tomoko Kawashima et al.   Biointerphases

Human epidermal stem cell differentiation is modulated by specific lipid subspecies

(2020) Matteo Vietri Rudan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein identification by 3D OrbiSIMS to facilitate in situ imaging and depth profiling

(2020) Anna M. Kotowska et al.   Nature Communications

Enhanced vitamin C skin permeation from supramolecular hydrogels, illustrated using in situ ToF-SIMS 3D chemical profiling

(2019) Nichola J. Starr et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Insight into imiquimod skin permeation and increased delivery using microneedle pre-treatment

(2019) Mohammed Hussain Al-Mayahy et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Determination of fatty acid and sphingoid base composition of eleven ceramide subclasses in stratum corneum by UHPLC/scheduled-MRM

(2018) Gilbert P. Laffet et al.   Metabolomics

Identification of lipids of the stratum corneum by high performance thin layer chromatography and mass spectrometry

(2018) Emilien L Jamin et al.   EUROPEAN JOURNAL OF MASS SPECTROMETRY

Imaging the distribution of skin lipids and topically applied compounds in human skin using mass spectrometry

(2018) Peter Sjövall et al.   Scientific Reports

The 3D OrbiSIMS—label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power

(2017) Melissa K Passarelli et al.   NATURE METHODS

Fatty acids penetration into human skin ex vivo: A TOF-SIMS analysis approach

(2017) Vytis Čižinauskas et al.   Biointerphases

Multivariate analysis of 3D ToF-SIMS images: method validation and application to cultured neuronal networks

(2016) S. Van Nuffel et al.   ANALYST

Age-Related Changes to Human Stratum Corneum Lipids Detected Using Time-of-Flight Secondary Ion Mass Spectrometry Following in Vivo Sampling

(2016) Nichola J. Starr et al.   ANALYTICAL CHEMISTRY

Imaging of Distribution of Topically Applied Drug Molecules in Mouse Skin by Combination of Time-of-Flight Secondary Ion Mass Spectrometry and Scanning Electron Microscopy

(2014) Peter Sjövall et al.   ANALYTICAL CHEMISTRY

Age-dependent changes in stratum corneum barrier function

(2014) E. Boireau-Adamezyk et al.   SKIN RESEARCH AND TECHNOLOGY

Combined LC/MS-platform for analysis of all major stratum corneum lipids, and the profiling of skin substitutes

(2013) Jeroen van Smeden et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The important role of stratum corneum lipids for the cutaneous barrier function

(2013) J. van Smeden et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients

(2013) Jeroen van Smeden et al.   EXPERIMENTAL DERMATOLOGY

Distribution and Visualisation of Chlorhexidine Within the Skin Using ToF-SIMS: A Potential Platform for the Design of More Efficacious Skin Antiseptic Formulations

(2013) Amy M. Judd et al.   PHARMACEUTICAL RESEARCH

Effect of ethnicity, gender and age on the amount and composition of residual skin surface components derived from sebum, sweat and epidermal lipids

(2013) Satyajit S. Shetage et al.   SKIN RESEARCH AND TECHNOLOGY

The stratum corneum comprises three layers with distinct metal-ion barrier properties

(2013) Akiharu Kubo et al.   Scientific Reports

Stratum corneum fatty acids: their critical role in preserving barrier integrity during cleansing

(2013) K.P. Ananthapadmanabhan et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

The structure and function of the stratum corneum

(2012) Gopinathan K. Menon et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Solar UV radiation reduces the barrier function of human skin

(2012) K. Biniek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered epidermal lipid layers induced by long-term exposure to suberythemal-dose ultraviolet

(2011) Hana Bak et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Changes in the Ceramide Profile of Atopic Dermatitis Patients

(2010) Junko Ishikawa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Fixation and Drying Protocols for the Preparation of Cell Samples for Time-of-Flight Secondary Ion Mass Spectrometry Analysis

(2009) Jakob Malm et al.   ANALYTICAL CHEMISTRY

A cosmetic ‘anti-ageing’ product improves photoaged skin: a double-blind, randomized controlled trial

(2009) R.E.B. Watson et al.   BRITISH JOURNAL OF DERMATOLOGY

Filaggrin in the frontline: role in skin barrier function and disease

(2009) A. Sandilands et al.   JOURNAL OF CELL SCIENCE

The tape stripping procedure – evaluation of some critical parameters

(2008) J. Lademann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Pig and guinea pig skin as surrogates for human in vitro penetration studies: A quantitative review

(2008) Ana M. Barbero et al.   TOXICOLOGY IN VITRO