P2X7 receptor agonists pre- and postcondition the heart against ischemia-reperfusion injury by opening pannexin-1/P2X7 channels

Ischemic preconditioning requires opening of pannexin-1/P2X7 channels not only during preconditioning but again after index ischemia at full reperfusion

(2011) Donald A. Vessey et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Postconditioning and protection from reperfusion injury: where do we stand? * Position Paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology

(2010) M. Ovize et al.   CARDIOVASCULAR RESEARCH

Pannexin-I/P2X 7 Purinergic Receptor Channels Mediate the Release of Cardioprotectants Induced by Ischemic Pre- and Postconditioning

(2010) Donald A. Vessey et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning

(2009) Donald A. Vessey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiac regulation by phosphoinositide 3-kinases and PTEN

(2009) G. Y. Oudit et al.   CARDIOVASCULAR RESEARCH

Involvement of P2Y receptors in pyridoxal-5′-phosphate-induced cardiac preconditioning

(2009) Hervé Millart et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Activation of purinergic receptors by ATP induces ventricular tachycardia by membrane depolarization and modifications of Ca2+ homeostasis

(2009) Iman S. Gurung et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

P2X7 receptor-Pannexin1 complex: pharmacology and signaling

(2008) R. Iglesias et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP

(2008) Feng Qiu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Signaling at Purinergic P2X Receptors

(2008) Annmarie Surprenant et al.   Annual Review of Physiology

Combined sphingosine, S1P and ischemic postconditioning rescue the heart after protracted ischemia

(2008) Donald A. Vessey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sphingosine can pre- and post-condition heart and utilizes a different mechanism from sphingosine 1-phosphate

(2008) Donald A. Vessey et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Pharmacological Characterization of Pannexin-1 Currents Expressed in Mammalian Cells

(2008) W. Ma et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury

(2008) Elizabeth Murphy et al.   PHYSIOLOGICAL REVIEWS