A Novel Approach to Block HIV-1 Coreceptor CXCR4 in Non-toxic Manner

Creating genetic resistance to HIV

(2012) John C Burnett et al.   CURRENT OPINION IN IMMUNOLOGY

Generation of an HIV-1-Resistant Immune System with CD34+ Hematopoietic Stem Cells Transduced with a Triple-Combination Anti-HIV Lentiviral Vector

(2012) J. E. Walker et al.   JOURNAL OF VIROLOGY

Lens Epithelium-derived Growth Factor/p75 Qualifies as a Target for HIV Gene Therapy in the NSG Mouse Model

(2012) Sofie Vets et al.   MOLECULAR THERAPY

A competitive cell growth assay for the detection of subtle effects of gene transduction on cell proliferation

(2011) J J M Eekels et al.   GENE THERAPY

Host factors mediating HIV-1 replication

(2011) Brian M. Friedrich et al.   VIRUS RESEARCH

Engineering HIV-Resistant Human CD4+ T Cells with CXCR4-Specific Zinc-Finger Nucleases

(2011) Craig B. Wilen et al.   PLoS Pathogens

Long-term inhibition of HIV-1 replication with RNA interference against cellular co-factors

(2010) Julia J.M. Eekels et al.   ANTIVIRAL RESEARCH

Evidence for the cure of HIV infection by CCR5 32/ 32 stem cell transplantation

(2010) K. Allers et al.   BLOOD

CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells

(2010) S. Jahnichen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Based Gene Therapy for HIV with Lentiviral Vector-Modified CD34+ Cells in Patients Undergoing Transplantation for AIDS-Related Lymphoma

(2010) D. L. DiGiusto et al.   Science Translational Medicine

Coreceptors and HIV-1 Pathogenesis

(2010) Paul R. Gorry et al.   Current HIV/AIDS Reports

Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivo

(2009) H-P Kiem et al.   GENE THERAPY

Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells

(2009) Ronald T Mitsuyasu et al.   NATURE MEDICINE

Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation

(2009) Gero Hütter et al.   NEW ENGLAND JOURNAL OF MEDICINE

The biology of CCR5 and CXCR4

(2009) Ghalib Alkhatib   Current Opinion in HIV and AIDS

Dissection of a co-translational nascent chain separation event

(2008) Victoria A. Doronina et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Generation of a stable mammalian cell line for simultaneous expression of multiple genes by using 2A peptide-based lentiviral vector

(2008) Tao Hu et al.   BIOTECHNOLOGY LETTERS

Lentiviral Vector Design for Multiple shRNA Expression and Durable HIV-1 Inhibition

(2008) Olivier ter Brake et al.   MOLECULAR THERAPY

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

(2008) Elena E Perez et al.   NATURE BIOTECHNOLOGY