CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity
Authors
Keywords
-
Journal
NUCLEIC ACIDS RESEARCH
Volume 41, Issue 20, Pages 9584-9592
Publisher
Oxford University Press (OUP)
Online
2013-08-13
DOI
10.1093/nar/gkt714
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
- (2013) Haoyi Wang et al. CELL
- Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease
- (2013) Scott J. Gratz et al. GENETICS
- Targeted chromosomal deletions and inversions in zebrafish
- (2013) A. Gupta et al. GENOME RESEARCH
- DNA targeting specificity of RNA-guided Cas9 nucleases
- (2013) Patrick D Hsu et al. NATURE BIOTECHNOLOGY
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
- (2013) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- RNA-guided editing of bacterial genomes using CRISPR-Cas systems
- (2013) Wenyan Jiang et al. NATURE BIOTECHNOLOGY
- Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish
- (2013) An Xiao et al. NUCLEIC ACIDS RESEARCH
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- RNA-programmed genome editing in human cells
- (2013) Martin Jinek et al. eLife
- Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects
- (2012) Cherie L. Ramirez et al. NUCLEIC ACIDS RESEARCH
- Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
- (2012) G. Gasiunas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Genetic engineering of human pluripotent cells using TALE nucleases
- (2011) Dirk Hockemeyer et al. NATURE BIOTECHNOLOGY
- Knockout rats generated by embryo microinjection of TALENs
- (2011) Laurent Tesson et al. NATURE BIOTECHNOLOGY
- An unbiased genome-wide analysis of zinc-finger nuclease specificity
- (2011) Richard Gabriel et al. NATURE BIOTECHNOLOGY
- Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection
- (2011) Vikram Pattanayak et al. NATURE METHODS
- The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli
- (2011) Rimantas Sapranauskas et al. NUCLEIC ACIDS RESEARCH
- A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
- (2011) Claudio Mussolino et al. NUCLEIC ACIDS RESEARCH
- The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
- (2010) Josiane E. Garneau et al. NATURE
- CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea
- (2010) Luciano A. Marraffini et al. NATURE REVIEWS GENETICS
- Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions
- (2010) Amy Marie Yu et al. NUCLEIC ACIDS RESEARCH
- CRISPR/Cas, the Immune System of Bacteria and Archaea
- (2010) P. Horvath et al. SCIENCE
- RNA-Guided RNA Cleavage by a CRISPR RNA-Cas Protein Complex
- (2009) Caryn R. Hale et al. CELL
- Targeted chromosomal deletions in human cells using zinc finger nucleases
- (2009) H. J. Lee et al. GENOME RESEARCH
- Short motif sequences determine the targets of the prokaryotic CRISPR defence system
- (2009) MICROBIOLOGY-SGM
- Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases
- (2009) Aron M. Geurts et al. SCIENCE
- Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
- (2008) Elena E Perez et al. NATURE BIOTECHNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started