A protein polymerization cascade mediates toxicity of non-pathological human huntingtin in yeast

Proteins with Intrinsically Disordered Domains Are Preferentially Recruited to Polyglutamine Aggregates

(2015) Maggie P. Wear et al.   PLoS One

Polyglutamine-Rich Suppressors of Huntingtin Toxicity Act Upstream of Hsp70 and Sti1 in Spatial Quality Control of Amyloid-Like Proteins

(2014) Katie J. Wolfe et al.   PLoS One

Proteomic Screening for Amyloid Proteins

(2014) Anton A. Nizhnikov et al.   PLoS One

Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1

(2014) C. Kayatekin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequestration of Sup35 by Aggregates of huntingtin Fragments Causes Toxicity of [PSI+] Yeast

(2012) Xiaohong Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-Mediated Sequestration of Essential Proteins Contributes to Mutant Huntingtin Toxicity in Yeast

(2012) Natalia V. Kochneva-Pervukhova et al.   PLoS One

The Effects of Amino Acid Composition of Glutamine-Rich Domains on Amyloid Formation and Fragmentation

(2012) Alexander I. Alexandrov et al.   PLoS One

DNA aptamers detecting generic amyloid epitopes

(2012) Olga V. Mitkevich et al.   Prion

Polyglutamine Toxicity Is Controlled by Prion Composition and Gene Dosage in Yeast

(2012) He Gong et al.   PLoS Genetics

Fluorescence Correlation Spectroscopy: Past, Present, Future

(2011) Elliot L. Elson   BIOPHYSICAL JOURNAL

Unexpected link between anaphase promoting complex and the toxicity of expanded polyglutamines expressed in yeast

(2011) Natalia A. Bocharova et al.   CELL CYCLE

Huntingtin Aggregation Kinetics and Their Pathological Role in a Drosophila Huntington’s Disease Model

(2011) Kurt R. Weiss et al.   GENETICS

Suicidal [PSI+] is a lethal yeast prion

(2011) R. P. McGlinchey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease

(2010) Christian Landles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo evidence for the fibrillar structures of Sup35 prions in yeast cells

(2010) Shigeko Kawai-Noma et al.   JOURNAL OF CELL BIOLOGY

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Interdependence of amyloid formation in yeast

(2010) Valery N. Urakov et al.   Prion

Polyglutamine Diseases: Where does Toxicity Come from? What is Toxicity? Where are We Going?

(2010) T. Takahashi et al.   Journal of Molecular Cell Biology

Normal and mutant HTT interact to affect clinical severity and progression in Huntington disease

(2009) N. A. Aziz et al.   NEUROLOGY

Peak intensity analysis as a method for estimation of fluorescent probe binding to artificial and natural nanoparticles: Tetramethylrhodamine uptake by isolated mitochondria

(2008) I.V. Perevoshchikova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

(2008) M. L. Duennwald et al.   GENES & DEVELOPMENT

Appearance and Propagation of Polyglutamine-based Amyloids in Yeast

(2008) Ilya M. Alexandrov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY