Polyglutamine Toxicity Is Controlled by Prion Composition and Gene Dosage in Yeast

Modeling Huntington disease in yeast: Perspectives and future directions

(2012) Robert P. Mason et al.   Prion

Polyglutamine misfolding in yeast: Toxic and protective aggregation

(2012) Martin L. Duennwald   Prion

Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions

(2011) Heidi Olzscha et al.   CELL

Destabilization and Recovery of a Yeast Prion after Mild Heat Shock

(2011) Gary P. Newnam et al.   JOURNAL OF MOLECULAR BIOLOGY

Neurotoxic protein oligomerisation associated with polyglutamine diseases

(2010) Sarah L. Hands et al.   ACTA NEUROPATHOLOGICA

Parkin-mediated ubiquitin signalling in aggresome formation and autophagy

(2010) Lih-Shen Chin et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The ubiquitous role of ubiquitin in the DNA damage response

(2010) Abdallah Al-Hakim et al.   DNA REPAIR

Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction

(2010) T. Yamanaka et al.   HUMAN MOLECULAR GENETICS

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Recruitment of the oncoprotein v-ErbA to aggresomes

(2010) Cornelius Bondzi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Repeat expansion disease: progress and puzzles in disease pathogenesis

(2010) Albert R. La Spada et al.   NATURE REVIEWS GENETICS

Interdependence of amyloid formation in yeast

(2010) Valery N. Urakov et al.   Prion

Sequestration of essential proteins causes prion associated toxicity in yeast

(2009) Namitha Vishveshwara et al.   MOLECULAR MICROBIOLOGY

Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis

(2009) Rakesh Kumar Singh et al.   NATURE CELL BIOLOGY

Huntingtin as an essential integrator of intracellular vesicular trafficking

(2009) Juliane P. Caviston et al.   TRENDS IN CELL BIOLOGY

Aggresome Formation and Neurodegenerative Diseases: Therapeutic Implications

(2008) L. Chin et al.   CURRENT MEDICINAL CHEMISTRY

Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery

(2008) Yan Wang et al.   FASEB JOURNAL

Rapamycin Inhibits Polyglutamine Aggregation Independently of Autophagy by Reducing Protein Synthesis

(2008) M. A. King et al.   MOLECULAR PHARMACOLOGY

Misfolded proteins partition between two distinct quality control compartments

(2008) Daniel Kaganovich et al.   NATURE

The yeast Sup35NM domain propagates as a prion in mammalian cells

(2008) C. Krammer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Double-strand breaks associated with repetitive DNA can reshape the genome

(2008) J. L. Argueso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA