Direct cloning and heterologous expression of the salinomycin biosynthetic gene cluster from Streptomyces albus DSM41398 in Streptomyces coelicolor A3(2)

Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin

(2015) Yongjun Zhou et al.   CHEMISTRY & BIOLOGY

A Versatile Microfluidic Device for Automating Synthetic Biology

(2015) Steve C. C. Shih et al.   ACS Synthetic Biology

Heterologous Production of Glidobactins/Luminmycins inEscherichia coliNissle Containing the Glidobactin Biosynthetic Gene Cluster fromBurkholderiaDSM7029

(2014) Xiaoying Bian et al.   CHEMBIOCHEM

Biosynthesis of magnetic nanostructures in a foreign organism by transfer of bacterial magnetosome gene clusters

(2014) Isabel Kolinko et al.   Nature Nanotechnology

Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A

(2014) Kazuya Yamanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Titer Heterologous Production in E. coli of Lyngbyatoxin, a Protein Kinase C Activator from an Uncultured Marine Cyanobacterium

(2013) Sarah E. Ongley et al.   ACS Chemical Biology

An Improved Method for oriT-Directed Cloning and Functionalization of Large Bacterial Genomic Regions

(2013) B. H. Kvitko et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

In Vivo Evidence for a Prodrug Activation Mechanism during Colibactin Maturation

(2013) Xiaoying Bian et al.   CHEMBIOCHEM

Improved seamless mutagenesis by recombineering using ccdB for counterselection

(2013) Hailong Wang et al.   NUCLEIC ACIDS RESEARCH

Role of a Conserved Arginine Residue in Linkers between the Ketosynthase and Acyltransferase Domains of Multimodular Polyketide Synthases

(2012) Satoshi Yuzawa et al.   BIOCHEMISTRY

Direct Cloning, Genetic Engineering, and Heterologous Expression of the Syringolin Biosynthetic Gene Cluster inE. colithrough Red/ET Recombineering

(2012) Xiaoying Bian et al.   CHEMBIOCHEM

Luminmycins A–C, Cryptic Natural Products from Photorhabdus luminescens Identified by Heterologous Expression in Escherichia coli

(2012) Xiaoying Bian et al.   JOURNAL OF NATURAL PRODUCTS

Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting

(2012) Jun Fu et al.   NATURE BIOTECHNOLOGY

Cloning and Characterization of the Polyether Salinomycin Biosynthesis Gene Cluster of Streptomyces albus XM211

(2011) Chunyan Jiang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Late-Stage Intermediate in Salinomycin Biosynthesis Is Revealed by Specific Mutation in the Biosynthetic Gene Cluster

(2011) Marie E. Yurkovich et al.   CHEMBIOCHEM

DNA assembly for synthetic biology: from parts to pathways and beyond

(2011) Tom Ellis et al.   Integrative Biology

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

(2011) Desheng Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tandem assembly of the epothilone biosynthetic gene cluster by in vitro site-specific recombination

(2011) Lin Zhang et al.   Scientific Reports

Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein

(2010) Ju-Hwa Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

In-Fusion BioBrick assembly and re-engineering

(2010) Sean C. Sleight et al.   NUCLEIC ACIDS RESEARCH

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Conformational Adaptability of Redβ during DNA Annealing and Implications for Its Structural Relationship with Rad52

(2009) Axel Erler et al.   JOURNAL OF MOLECULAR BIOLOGY

Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds

(2009) John A. McIntosh et al.   NATURAL PRODUCT REPORTS

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition

(2008) Jun Fu et al.   NUCLEIC ACIDS RESEARCH

Intergeneric conjugation in holomycin-producing marine Streptomyces sp. strain M095

(2006) Yan-Hua Hou et al.   MICROBIOLOGICAL RESEARCH