Activity of andrographolide against chikungunya virus infection

Inflammasome signaling pathways exert antiviral effect against Chikungunya virus in human dermal fibroblasts

(2015) Peeraya Ekchariyawat et al.   INFECTION GENETICS AND EVOLUTION

Chikungunya virus non-structural protein 2-mediated host shut-off disables the unfolded protein response

(2015) Jelke J. Fros et al.   JOURNAL OF GENERAL VIROLOGY

Activity of Andrographolide and Its Derivatives on HPV16 Pseudovirus Infection and Viral Oncogene Expression in Cervical Carcinoma Cells

(2015) Tipaya Ekalaksananan et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

SRS06, a New Semisynthetic Andrographolide Derivative with Improved Anticancer Potency and Selectivity, Inhibits Nuclear Factor-κB Nuclear Binding in the A549 Non-Small Cell Lung Cancer Cell Line

(2015) Jonathan Chee Woei Lim et al.   PHARMACOLOGY

Chikungunya on the move

(2015) Michael A. Johansson   TRENDS IN PARASITOLOGY

Synthesis, structure–activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents

(2014) Hao Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Andrographolide as an Anti-H1N1 drug and the mechanism related to retinoic acid-inducible gene-I-like receptors signaling pathway

(2014) Bin Yu et al.   Chinese Journal of Integrative Medicine

Andrographolide sodium bisulfate-induced apoptosis and autophagy in human proximal tubular endothelial cells is a ROS-mediated pathway

(2014) Hong Lu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Identification of chikungunya virus interacting proteins in mammalian cells

(2014) Mandar S Paingankar et al.   JOURNAL OF BIOSCIENCES

Modulation of thioacetamide-induced hepatic inflammations, angiogenesis and fibrosis by andrographolide in mice

(2014) Tzung-Yan Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Comprehensive proteomic analysis of white blood cells from chikungunya fever patients of different severities

(2014) Nitwara Wikan et al.   Journal of Translational Medicine

Andrographolide inhibits melanoma tumor growth by inactivating the TLR4/NF-κB signaling pathway

(2014) Qian-Qian Zhang et al.   MELANOMA RESEARCH

A Quantitative Chemical Proteomics Approach to Profile the Specific Cellular Targets of Andrographolide, a Promising Anticancer Agent That Suppresses Tumor Metastasis

(2014) Jigang Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Review on Liver Inflammation and Antiinflammatory Activity ofAndrographis paniculatafor Hepatoprotection

(2014) Lee Suan Chua   PHYTOTHERAPY RESEARCH

Andrographolide interferes quorum sensing to reduce cell damage caused by avian pathogenic Escherichia coli

(2014) Xun Guo et al.   VETERINARY MICROBIOLOGY

Chikungunya fever: Epidemiology, clinical syndrome, pathogenesis and therapy

(2013) Simon-Djamel Thiberville et al.   ANTIVIRAL RESEARCH

Andrographolide exerts anti-hepatitis C virus activity by up-regulating haeme oxygenase-1 via the p38 MAPK/Nrf2 pathway in human hepatoma cells

(2013) Jin-Ching Lee et al.   BRITISH JOURNAL OF PHARMACOLOGY

Species-specific impact of the autophagy machinery on Chikungunya virus infection

(2013) Delphine Judith et al.   EMBO REPORTS

Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation

(2013) Abhay P S Rathore et al.   Virology Journal

Inhibition of Chikungunya Virus Replication by Harringtonine, a Novel Antiviral That Suppresses Viral Protein Expression

(2012) Parveen Kaur et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Andrographolide sensitizes cisplatin-induced apoptosis via suppression of autophagosome-lysosome fusion in human cancer cells

(2012) Jing Zhou et al.   Autophagy

Andrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition pore

(2012) Wei Chen et al.   CARCINOGENESIS

Chikungunya virus–induced autophagy delays caspase-dependent cell death

(2012) Pierre-Emmanuel Joubert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of prohibitin as a Chikungunya virus receptor protein

(2012) Phitchayapak Wintachai et al.   JOURNAL OF MEDICAL VIROLOGY

Chikungunya Virus Infection of Cell Lines: Analysis of the East, Central and South African Lineage

(2012) Nitwara Wikan et al.   PLoS One

Chikungunya Disease: Infection-Associated Markers from the Acute to the Chronic Phase of Arbovirus-Induced Arthralgia

(2012) Laurence Dupuis-Maguiraga et al.   PLoS Neglected Tropical Diseases

Chikungunya in Southeast Asia: understanding the emergence and finding solutions

(2011) Rojjanaporn Pulmanausahakul et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

A Potential Andrographolide Analogue against the Replication of Herpes Simplex Virus Type 1 in Vero Cells

(2011) Supawadee Seubsasana et al.   Medicinal Chemistry

Differential proteome analysis of Chikungunya virus-infected new-born mice tissues reveal implication of stress, inflammatory and apoptotic pathways in disease pathogenesis

(2011) Rekha Dhanwani et al.   PROTEOMICS

Chikungunya triggers an autophagic process which promotes viral replication

(2011) Pascale Krejbich-Trotot et al.   Virology Journal

Chikungunya

(2010) Ann M. Powers   CLINICS IN LABORATORY MEDICINE

Tracing the path of Chikungunya virus—Evolution and adaptation

(2010) Lee Ching Ng et al.   INFECTION GENETICS AND EVOLUTION

A nonhuman primate model of chikungunya disease

(2010) Stephen Higgs et al.   JOURNAL OF CLINICAL INVESTIGATION

The inflammasome regulatory pathway and infections: Role in pathophysiology and clinical implications

(2010) Ryosuke Osawa et al.   JOURNAL OF INFECTION

Phosphatidylinositol 3-Kinase-, Actin-, and Microtubule-Dependent Transport of Semliki Forest Virus Replication Complexes from the Plasma Membrane to Modified Lysosomes

(2010) P. Spuul et al.   JOURNAL OF VIROLOGY

Biology and pathogenesis of chikungunya virus

(2010) Olivier Schwartz et al.   NATURE REVIEWS MICROBIOLOGY

Activity of Andrographolide and Its Derivatives against Influenza Virus in Vivo and in Vitro

(2009) Jian-Xin Chen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Re-emergence of Chikungunya virus in South-east Asia: virological evidence from Sri Lanka and Singapore

(2009) H. C. Hapuarachchi et al.   JOURNAL OF GENERAL VIROLOGY

Epistatic Roles of E2 Glycoprotein Mutations in Adaption of Chikungunya Virus to Aedes Albopictus and Ae. Aegypti Mosquitoes

(2009) Konstantin A. Tsetsarkin et al.   PLoS One

Chikungunya fever: CNS infection and pathologies of a re-emerging arbovirus

(2009) Trina Das et al.   PROGRESS IN NEUROBIOLOGY

Chikungunya virus adapts to tiger mosquito via evolutionary convergence: a sign of things to come?

(2008) Xavier de Lamballerie et al.   Virology Journal

Comparative full genome analysis revealed E1: A226V shift in 2007 Indian Chikungunya virus isolates

(2008) S.R. Santhosh et al.   VIRUS RESEARCH