IRGM1 enhances B16 melanoma cell metastasis through PI3K-Rac1 mediated epithelial mesenchymal transition
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
IRGM1 enhances B16 melanoma cell metastasis through PI3K-Rac1 mediated epithelial mesenchymal transition
Authors
Keywords
-
Journal
Scientific Reports
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-07-23
DOI
10.1038/srep12357
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mechanisms of interferon-beta-induced inhibition ofToxoplasma gondiigrowth in murine macrophages and embryonic fibroblasts: role of immunity-related GTPase M1
- (2015) Motamed Elsayed Mahmoud et al. CELLULAR MICROBIOLOGY
- IFNg-induced Irgm1 promotes tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1-dependent autophagy
- (2015) H Dong et al. ONCOGENE
- C6-ceramide nanoliposome suppresses tumor metastasis by eliciting PI3K and PKCζ tumor-suppressive activities and regulating integrin affinity modulation
- (2015) Pu Zhang et al. Scientific Reports
- PI3K signalling is required for a TGFβ-induced epithelial-mesenchymal-like transition (EMT-like) in human melanoma cells
- (2014) Natalie C. Schlegel et al. EXPERIMENTAL DERMATOLOGY
- A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma
- (2013) Julie Caramel et al. CANCER CELL
- Tumor metastasis: moving new biological insights into the clinic
- (2013) Liling Wan et al. NATURE MEDICINE
- PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1
- (2013) H. Ebi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RAC1P29S is a spontaneously activating cancer-associated GTPase
- (2013) M. J. Davis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immune-related GTPase M (IRGM1) regulates neuronal autophagy in a mouse model of stroke
- (2012) Shuyu He et al. Autophagy
- Immune-related GTPase Irgm1 exacerbates experimental auto-immune encephalomyelitis by promoting the disruption of blood–brain barrier and blood–cerebrospinal fluid barrier
- (2012) Chaodong Wang et al. MOLECULAR IMMUNOLOGY
- Mutant B-RAF regulates a Rac-dependent cadherin switch in melanoma
- (2012) E Monaghan-Benson et al. ONCOGENE
- PI3K p110α Isoform-Dependent Rho GTPase Rac1 Activation Mediates H2S-Promoted Endothelial Cell Migration via Actin Cytoskeleton Reorganization
- (2012) Li-Jia Zhang et al. PLoS One
- Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling
- (2011) K. Y. King et al. BLOOD
- A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
- (2011) Patrick Brest et al. NATURE GENETICS
- Rac and Rho GTPases in cancer cell motility control
- (2010) Matteo Parri et al. Cell Communication and Signaling
- Genetic deficiency of Irgm1 (LRG-47) suppresses induction of experimental autoimmune encephalomyelitis by promoting apoptosis of activated CD4+ T cells
- (2010) Hongwei Xu et al. FASEB JOURNAL
- The PI3K p110α isoform regulates endothelial adherens junctions via Pyk2 and Rac1
- (2010) Robert J. Cain et al. JOURNAL OF CELL BIOLOGY
- Interferon-inducible immunity-related GTPase Irgm1 regulates IFNγ-dependent host defense, lymphocyte survival and autophagy
- (2009) Carl G. Feng et al. Autophagy
- Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway
- (2009) Dong-Hoon Shin et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Biomarkers for epithelial-mesenchymal transitions
- (2009) Michael Zeisberg et al. JOURNAL OF CLINICAL INVESTIGATION
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Regulation of macrophage motility by Irgm1
- (2009) Stanley C. Henry et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P2 and PtdIns(3,4,5)P3 promotes immunity to mycobacteria
- (2009) Sangeeta Tiwari et al. NATURE IMMUNOLOGY
- Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
- (2008) Steven A McCarroll et al. NATURE GENETICS
- The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-γ-induced cell death
- (2008) Carl G Feng et al. NATURE IMMUNOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started