A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migration

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Autophagy and Crohns Disease: At the Crossroads of Infection, Inflammation, Immunity, and Cancer

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Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

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Differential expression and regulation of ADAM17 and TIMP3 in acute inflamed intestinal epithelia

(2009) Annabelle Cesaro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Crohn's disease-associated adherent-invasiveE. coliare selectively favoured by impaired autophagy to replicate intracellularly

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Tandem affinity purification of miRNA target mRNAs (TAP-Tar)

(2009) Nora Nonne et al.   NUCLEIC ACIDS RESEARCH

Death and Resurrection of the Human IRGM Gene

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NF-kappaB p65-Dependent Transactivation of miRNA Genes following Cryptosporidium parvum Infection Stimulates Epithelial Cell Immune Responses

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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

(2008) Steven A McCarroll et al.   NATURE GENETICS

Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant

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