IL-18 Attenuates Experimental Choroidal Neovascularization as a Potential Therapy for Wet Age-Related Macular Degeneration
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Title
IL-18 Attenuates Experimental Choroidal Neovascularization as a Potential Therapy for Wet Age-Related Macular Degeneration
Authors
Keywords
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Journal
Science Translational Medicine
Volume 6, Issue 230, Pages 230ra44-230ra44
Publisher
American Association for the Advancement of Science (AAAS)
Online
2014-04-03
DOI
10.1126/scitranslmed.3007616
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- (2012) Sarah L Doyle et al. NATURE MEDICINE
- Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration
- (2012) Jeffrey S. Heier et al. OPHTHALMOLOGY
- Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration
- (2011) Kati Kinnunen et al. ACTA OPHTHALMOLOGICA
- Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
- (2011) James Harris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration
- (2011) NEW ENGLAND JOURNAL OF MEDICINE
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells
- (2010) Tim U. Krohne et al. EXPERIMENTAL EYE RESEARCH
- Transcriptome analysis and molecular signature of human retinal pigment epithelium
- (2010) N.V. Strunnikova et al. HUMAN MOLECULAR GENETICS
- Animal models of choroidal and retinal neovascularization
- (2010) Hans E. Grossniklaus et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Forecasting Age-Related Macular Degeneration Through the Year 2050
- (2009) David B. Rein ARCHIVES OF OPHTHALMOLOGY
- A phase 2, randomized study of SB-485232, rhIL-18, in patients with previously untreated metastatic melanoma
- (2009) Ahmad A. Tarhini et al. CANCER
- Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
- (2009) F. G. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- Autophagy and Exosomes in the Aged Retinal Pigment Epithelium: Possible Relevance to Drusen Formation and Age-Related Macular Degeneration
- (2009) Ai Ling Wang et al. PLoS One
- A Dose-Escalation Study of Recombinant Human Interleukin-18 Using Two Different Schedules of Administration in Patients with Cancer
- (2008) M. J. Robertson et al. CLINICAL CANCER RESEARCH
- Age-Related Macular Degeneration
- (2008) Rama D. Jager et al. NEW ENGLAND JOURNAL OF MEDICINE
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