Activation Loop Dynamics Determine the Different Catalytic Efficiencies of B Cell- and T Cell-Specific Tec Kinases

The Role of Tec Family Kinases in the Regulation of T-helper-cell Differentiation

(2012) Nicole Boucheron et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Tec Family Kinases in Inflammation and Disease

(2012) Nicole J. Horwood et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Substrate Recognition of PLCγ1 via a Specific Docking Surface on Itk

(2012) Qian Xie et al.   JOURNAL OF MOLECULAR BIOLOGY

Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes

(2012) Sung Hee Choi et al.   STRUCTURE

Interpretation of the Consequences of Mutations in Protein Kinases: Combined Use of Bioinformatics and Text Mining

(2012) Jose M. G. Izarzugaza et al.   Frontiers in Physiology

Identification of an Allosteric Signaling Network within Tec Family Kinases

(2010) Raji E. Joseph et al.   JOURNAL OF MOLECULAR BIOLOGY

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

(2010) Zhongqi Zhang et al.   PROTEIN SCIENCE

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry

(2010) Hui-Min Zhang et al.   PROTEIN SCIENCE

T-Cell Signaling Regulated by the Tec Family Kinase, Itk

(2010) A. H. Andreotti et al.   Cold Spring Harbor Perspectives in Biology

The structure, regulation, and function of ZAP-70

(2009) Byron B. Au-Yeung et al.   IMMUNOLOGICAL REVIEWS

Targeting protein kinases in central nervous system disorders

(2009) Laura K. Chico et al.   NATURE REVIEWS DRUG DISCOVERY

Sequence and Structure Signatures of Cancer Mutation Hotspots in Protein Kinases

(2009) Anshuman Dixit et al.   PLoS One

Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCγ1

(2009) Lie Min et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial expression and purification of Interleukin-2 Tyrosine kinase: Single step separation of the chaperonin impurity

(2008) Raji E. Joseph et al.   PROTEIN EXPRESSION AND PURIFICATION