Design, synthesis and mechanism of novel shikonin derivatives as potent anticancer agents
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Design, synthesis and mechanism of novel shikonin derivatives as potent anticancer agents
Authors
Keywords
-
Journal
RSC Advances
Volume 5, Issue 40, Pages 31759-31767
Publisher
Royal Society of Chemistry (RSC)
Online
2015-03-20
DOI
10.1039/c5ra01872b
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Novel Shikonin Derivatives Targeting Tubulin as Anticancer Agents
- (2014) Jing Guo et al. Chemical Biology & Drug Design
- Synthesis and biological evaluation of novel shikonin ester derivatives as potential anti-cancer agents
- (2014) Shahla Karim Baloch† et al. RSC Advances
- Design, synthesis and biological evaluation of shikonin thio-glycoside derivatives: new anti-tubulin agents
- (2014) Hong-Yan Lin et al. RSC Advances
- Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21Cip1 downregulation are required for shikonin-induced apoptosis
- (2013) Jiwon Ahn et al. APOPTOSIS
- Synthesis and Biological Evaluation of Heterocyclic Carboxylic Acyl Shikonin Derivatives
- (2013) Xiao-Ming Wang et al. Chemical Biology & Drug Design
- Design and Synthesis of Fluoroacylshikonin as an Anticancer Agent
- (2013) Wen-Yao Kong et al. CHIRALITY
- Shikonin exerts anti-inflammatory effects in a murine model of lipopolysaccharide-induced acute lung injury by inhibiting the nuclear factor-kappaB signaling pathway
- (2013) Dejie Liang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Shikonin attenuates lung cancer cell adhesion to extracellular matrix and metastasis by inhibiting integrin β1 expression and the ERK1/2 signaling pathway
- (2013) Heyong Wang et al. TOXICOLOGY
- Design, Synthesis and Biological Evaluation of Cinnamic Acyl Shikonin Derivatives
- (2012) Hong-Yan Lin et al. Chemical Biology & Drug Design
- The microtubule depolymerizing agent naphthazarin induces both apoptosis and autophagy in A549 lung cancer cells
- (2011) Bipul R. Acharya et al. APOPTOSIS
- Synthesis and antitumor activity of new shikonin glycosides
- (2010) Yehua Su et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Life and death partners: apoptosis, autophagy and the cross-talk between them
- (2009) A Eisenberg-Lerner et al. CELL DEATH AND DIFFERENTIATION
- Naturally-occurring shikonin analogues – A class of necroptotic inducers that circumvent cancer drug resistance
- (2008) Yanyan Xuan et al. CANCER LETTERS
- Modulation of Orphan Nuclear Receptor Nur77-Mediated Apoptotic Pathway by Acetylshikonin and Analogues
- (2008) Jie Liu et al. CANCER RESEARCH
- Mechanism of inhibition of tumor angiogenesis by β-hydroxyisovalerylshikonin
- (2008) Yusuke Komi et al. CANCER SCIENCE
- Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells
- (2008) Xin Mao et al. CELL RESEARCH
- Alkannins and Shikonins: A New Class of Wound Healing Agents
- (2008) V. Papageorgiou et al. CURRENT MEDICINAL CHEMISTRY
- Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4(3H)-quinazolinone analogs☆
- (2008) Abdulrahman M. Al-Obaid et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started