Envelope Deglycosylation Enhances Antigenicity of HIV-1 gp41 Epitopes for Both Broad Neutralizing Antibodies and Their Unmutated Ancestor Antibodies

Deglycosylation of HIV-1 AE Gp140 Enhances the Capacity to Elicit Neutralizing Antibodies Against the Heterologous HIV-1 Clade

(2010) Congyou Zhang et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

SoDA2: a Hidden Markov Model approach for identification of immunoglobulin rearrangements

(2010) S. Munshaw et al.   BIOINFORMATICS

Design of a Non-glycosylated Outer Domain-derived HIV-1 gp120 Immunogen That Binds to CD4 and Induces Neutralizing Antibodies

(2010) Sanchari Bhattacharyya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression-System-Dependent Modulation of HIV-1 Envelope Glycoprotein Antigenicity and Immunogenicity

(2010) Leopold Kong et al.   JOURNAL OF MOLECULAR BIOLOGY

Variable Loop Glycan Dependency of the Broad and Potent HIV-1-Neutralizing Antibodies PG9 and PG16

(2010) Katie J. Doores et al.   JOURNAL OF VIROLOGY

Role of Complex Carbohydrates in Human Immunodeficiency Virus Type 1 Infection and Resistance to Antibody Neutralization

(2010) J. M. Binley et al.   JOURNAL OF VIROLOGY

Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution

(2010) X. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions

(2010) E. M. Scherer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Signatures in the Envelope Glycoproteins of HIV-1 that Associate with Broadly Neutralizing Antibodies

(2010) S. Gnanakaran et al.   PLoS Computational Biology

A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals

(2010) Laura M. Walker et al.   PLoS Pathogens

Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: Implications for evasion of immune responses and design of vaccine immunogens

(2009) Xiaodong Xiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activating systemic autoimmunity: B's, T's, and tolls

(2009) Mark J Shlomchik   CURRENT OPINION IN IMMUNOLOGY

In Vivo gp41 Antibodies Targeting the 2F5 Monoclonal Antibody Epitope Mediate Human Immunodeficiency Virus Type 1 Neutralization Breadth

(2009) X. Shen et al.   JOURNAL OF VIROLOGY

Stable Docking of Neutralizing Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Monoclonal Antibodies 2F5 and 4E10 Is Dependent on the Membrane Immersion Depth of Their Epitope Regions

(2009) S. M. Dennison et al.   JOURNAL OF VIROLOGY

Relationship between Antibody 2F5 Neutralization of HIV-1 and Hydrophobicity of Its Heavy Chain Third Complementarity-Determining Region

(2009) G. Ofek et al.   JOURNAL OF VIROLOGY

Role of HIV membrane in neutralization by two broadly neutralizing antibodies

(2009) S. M. Alam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance

(2009) L. Verkoczy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins

(2009) Feng Gao et al.   VIROLOGY

Challenges for structure-based HIV vaccine design

(2009) William R Schief et al.   Current Opinion in HIV and AIDS

HIV-1 Hides an Achilles' Heel in Virion Lipids

(2008) Barton F. Haynes et al.   IMMUNITY

Glycosylation Site-Specific Analysis of HIV Envelope Proteins (JR-FL and CON-S) Reveals Major Differences in Glycosylation Site Occupancy, Glycoform Profiles, and Antigenic Epitopesʼ Accessibility

(2008) Eden P. Go et al.   JOURNAL OF PROTEOME RESEARCH

Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF MS for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein

(2008) Janet Irungu et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Glycosylation of gp41 of Simian Immunodeficiency Virus Shields Epitopes That Can Be Targets for Neutralizing Antibodies

(2008) E. Yuste et al.   JOURNAL OF VIROLOGY

Molecular architecture of native HIV-1 gp120 trimers

(2008) Jun Liu et al.   NATURE

Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN

(2008) S.-K. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies

(2008) G. Frey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancing Exposure of HIV-1 Neutralization Epitopes through Mutations in gp41

(2007) Catherine A Blish et al.   PLOS MEDICINE