Article
Oncology
John P. Kirkpatrick
Summary: This perspective discusses the challenges in managing brain metastases, requiring a comprehensive approach involving clinical evidence, patient goals, and interdisciplinary collaboration.
FRONTIERS IN ONCOLOGY
(2022)
Review
Biotechnology & Applied Microbiology
Trudy M. Wassenaar, David W. Ussery, Adriana Cabal Rosel
Summary: Omics research involves the collection and analysis of big data, which requires automated approaches. In the field of genomics, specialized software, quality control of input data, and simplification for visualization of results are necessary. Clear communication of big data analyses can be enhanced by novel visualization strategies. The interpretation of findings may be hindered by lack of understanding of analytical tools by microbiologists and limited knowledge of the biology of the microbes under study by researchers.
JOURNAL OF APPLIED MICROBIOLOGY
(2023)
Article
Neurosciences
Insoo Hyun, J. C. Scharf-Deering, Sarah Sullivan, John Dennis Aach, Paola Arlotta, Matthew L. Baum, George M. Church, Aaron Goldenberg, Henry T. Greely, Parastoo Khoshakhlagh, Richie E. Kohman, Melissa Lopes, Caroline Lowenthal, Aric Lu, Alex H. M. Ng, Sergiu P. Pasca, Bruna Paulsen, Martina Pigoni, Christopher T. Scott, David A. Silbersweig, Mark A. Skylar-Scott, Robert D. Truog, Jeantine E. Lunshof
Summary: By integrating ongoing bioethical collaboration, neuroscientists can have a positive impact on their research and the knowledge it generates. In this regard, the authors share their interdisciplinary model for promoting the ethical advancement of human neural organoid research.
NATURE NEUROSCIENCE
(2022)
Editorial Material
Biochemistry & Molecular Biology
Meghie Rodrigues, Simon Manga
Summary: Early-career researchers discuss their top priorities in cancer research, which include early screening and immunotherapy, as well as the significance of nanotechnology and counseling.
Review
Microbiology
Todd Gray, Gisela Storz, Kai Papenfort
Summary: There has been increased recognition of the importance of small proteins, which were previously overlooked. Small proteins are stable within cells and have regulatory functions. Important questions about small proteins in bacteria and archaea are being addressed, and new identification approaches have been discussed.
JOURNAL OF BACTERIOLOGY
(2022)
Review
Cell & Tissue Engineering
Lance A. Mulder, Josse A. Depla, Adithya Sridhar, Katja Wolthers, Dasja Pajkrt, Renata Vieira de Sa
Summary: This study systematically reviewed human brain organoid publications from 2010 to 2020 and summarized the applications, culture methods, and differentiation strategies of different models. The results showed that calcium imaging and patch clamp analysis were commonly used for neuronal activity assays in brain organoids, and network activity varied depending on age, model, and assay. The study also provided insights into specific culture methods and differentiation strategies for different brain organoid models.
STEM CELL RESEARCH & THERAPY
(2023)
Biographical-Item
Immunology
Lucie Van Emmenis
Summary: Ruth Scherz-Shouval, an Assistant Professor at the Weizmann Institute of Science, investigates the tumor microenvironment, its response to stress, and cell-cell interactions within it.
JOURNAL OF EXPERIMENTAL MEDICINE
(2023)
Article
Pediatrics
Emily von Scheven, Bhupinder K. Nahal, Isabel C. Cohen, Rosa Kelekian, Linda S. Franck
Summary: The study aimed to identify research priorities for young people living with chronic illness and their caregivers. Findings showed that individuals with different chronic conditions were able to reach consensus on common research priorities, with age and role influencing these priorities. The Research Prioritization by Affected Communities (RPAC) method provided nuanced insights and highlighted under-studied topics for future research investments.
PEDIATRIC RESEARCH
(2021)
Article
Economics
Nicole Adler, Amir Brudner, Riccardo Gallotti, Filippo Privitera, Jose J. Ramasco
Summary: This study develops algorithms to analyze ICT data and estimate individuals' mobility at different spatial scales, as well as drivers of airport demand. Using evidence of consumer behavior and producers' financial data, a catchment area game is developed to analyze the potential impact of collaboration between airports and airlines. The results suggest that airline-airport vertical collusion is beneficial, while airport-airport horizontal collusion is less likely.
TRANSPORTATION RESEARCH PART B-METHODOLOGICAL
(2022)
Editorial Material
Biochemistry & Molecular Biology
Michael M. Bannert, Andreas Bartels
Summary: New research using functional magnetic resonance imaging data confirms the distinct response of anatomically distinct patches in the visual cortex to different categories of stimuli and discovers a new preference for food.
Review
Biochemistry & Molecular Biology
Ana Margarida Araujo, Felix Carvalho, Paula Guedes de Pinho, Marcia Carvalho
Summary: Toxicometabolomics is an emerging field in life sciences that focuses on using metabolomics to assess the hazards and risks of toxicants to organisms, providing new biomarkers and detailing the metabolic responses and altered biological pathways caused by stressful stimuli. This review discusses the analytical platforms and workflow used in toxicometabolomic studies, as well as recent exploratory research applying metabolomics in various areas of toxicology.
Article
Education & Educational Research
Mark Barrow, Barbara Grant, Linlin Xu
Summary: This article discusses the theoretical construction of academic identity and the research progress in related fields, finding that constructivist theories form the core resources for academic identity research. It also suggests the need to broaden the scope of research to generate new insights.
HIGHER EDUCATION RESEARCH & DEVELOPMENT
(2022)
Article
Management
Susanne Beck, Tiare-Maria Brasseur, Marion Poetz, Henry Sauermann
Summary: Scientists are increasingly involving the general public in their research, particularly in empirical work. However, it is unclear how the public can be involved in conceptual stages such as formulating research questions. This study analyzes data from two crowdsourcing projects in the medical sciences and finds that crowd contributions mainly restate problems, providing little guidance in terms of potential causes or solutions. Nevertheless, crowd-generated research questions frequently combine elements from different fields and have comparable practical impact. Professional evaluations suggest that crowd contributions have lower novelty and potential scientific impact than professional research questions, but outperform them when selection mechanisms are applied.
Review
Parasitology
Kittipong Chaisiri, Piyada Linsuwanon, Benjamin L. Makepeace
Summary: This passage discusses the importance of chiggers as vectors of diseases, and explores the diversity of chigger microbiota and potential interactions within this ecosystem.
TRENDS IN PARASITOLOGY
(2023)
Review
Medicine, Research & Experimental
Yujiro Yamada, Emily M. Frith, Vickie Wong, Robert W. Spitz, Zachary W. Bell, Raksha N. Chatakondi, Takashi Abe, Jeremy P. Loenneke
Summary: The effects of blood flow restricted exercise on cognition are still unclear due to limited research in this area. The hypothesis suggests that blood flow restricted exercise could potentially enhance cognitive domains through increases in lactate production, catecholamine concentration, and PGC-1 alpha expression. Further investigations are needed to test this hypothesis.
MEDICAL HYPOTHESES
(2021)
