Comparison of hydrocarbon-and lactam-bridged cyclic peptides as dimerization inhibitors of Leishmania infantum trypanothione reductase

Constraining Cyclic Peptides To Mimic Protein Structure Motifs

(2014) Timothy A. Hill et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fruitful Decade for Antileishmanial Compounds from 2002 to Late 2011

(2014) Hidayat Hussain et al.   CHEMICAL REVIEWS

Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

(2014) Loren D. Walensky et al.   JOURNAL OF MEDICINAL CHEMISTRY

Stapled peptide-based membrane fusion inhibitors of hepatitis C virus

(2013) Hong-Kui Cui et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Membrane Permeability of Hydrocarbon-Cross-Linked Peptides

(2013) Tzu-Lin Sun et al.   BIOPHYSICAL JOURNAL

Probing the Dimerization Interface ofLeishmania infantumTrypanothione Reductase with Site-Directed Mutagenesis and Short Peptides

(2013) Miguel A. Toro et al.   CHEMBIOCHEM

Trypanosomatidae Diseases: From the Current Therapy to the Efficacious Role of Trypanothione Reductase in Drug Discovery

(2013) L.S.C. Bernardes et al.   CURRENT MEDICINAL CHEMISTRY

New modalities in conformationally constrained peptides for potency, selectivity and cell permeation

(2013) Ram Dharanipragada   Future Medicinal Chemistry

Strategies for the design of orally bioavailable antileishmanial treatments

(2013) T.T.H. Pham et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Design of Cell-Permeable Stapled Peptides as HIV-1 Integrase Inhibitors

(2013) Ya-Qiu Long et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of α-helix-mediated protein–protein interactions using designed molecules

(2013) Valeria Azzarito et al.   Nature Chemistry

Helical peptides from VEGF and Vammin hotspots for modulating the VEGF–VEGFR interaction

(2013) María Isabel García-Aranda et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1

(2013) Tara Rao et al.   PLoS One

Stabilizing the Pro-Apoptotic BimBH3 Helix (BimSAHB) Does Not Necessarily Enhance Affinity or Biological Activity

(2012) Toru Okamoto et al.   ACS Chemical Biology

MM-ISMSA: An Ultrafast and Accurate Scoring Function for Protein–Protein Docking

(2012) Javier Klett et al.   Journal of Chemical Theory and Computation

Footprinting of Inhibitor Interactions ofIn SilicoIdentified Inhibitors of Trypanothione Reductase ofLeishmaniaParasite

(2012) Santhosh K. Venkatesan et al.   TheScientificWorldJOURNAL

Leishmaniasis: Current status of available drugs and new potential drug targets

(2012) Nisha Singh et al.   Asian Pacific Journal of Tropical Medicine

Disulfide and amide-bridged cyclic peptide analogues of the VEGF81–91 fragment: Synthesis, conformational analysis and biological evaluation

(2011) María Isabel García-Aranda et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Peptides and Proteins as a Continuing Exciting Source of Inspiration for Peptidomimetics

(2011) Rob M. J. Liskamp et al.   CHEMBIOCHEM

Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase

(2011) Michael H. Duyzend et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Lactam-Stabilized Helical Analogues of the Analgesic μ-Conotoxin KIIIA

(2011) Keith K. Khoo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography

(2011) Stephen Patterson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Leishmania antimony resistance: what we know what we can learn from the field

(2011) Khatima Aït-Oudhia et al.   PARASITOLOGY RESEARCH

A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53

(2010) Federico Bernal et al.   CANCER CELL

Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses

(2010) Aaron J. Oakley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

(2010) G. H. Bird et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A helix-turn motif in the C-terminal domain of histone H1

(2010) Roger Vila et al.   PROTEIN SCIENCE

Stereochemical effects of all-hydrocarbon tethers in i,i+4 stapled peptides

(2009) Young-Woo Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Improved Tricyclic Inhibitors of Trypanothione Reductase by Screening and Chemical Synthesis

(2009) John L. Richardson et al.   ChemMedChem

Peptidomimetics - A Versatile Route to Biologically Active Compounds

(2009) Andreas Grauer et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

All-Atom Model for Stabilization of α-Helical Structure in Peptides by Hydrocarbon Staples

(2009) Peter S. Kutchukian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct inhibition of the NOTCH transcription factor complex

(2009) Raymond E. Moellering et al.   NATURE

Metathesis in Peptides and Peptidomimetics

(2008) Ashraf Brik   ADVANCED SYNTHESIS & CATALYSIS

Contemporary strategies for the stabilization of peptides in the α-helical conformation

(2008) Laura K Henchey et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

(2008) Nika N Danial et al.   NATURE MEDICINE