Effectiveness of Tapentadol Prolonged Release (PR) Compared with Oxycodone/Naloxone PR for the Management of Severe Chronic Low Back Pain with a Neuropathic Component: A Randomized, Controlled, Open-Label, Phase 3b/4 Study

Controlled-Release Oxycodone and Naloxone in the Treatment of Chronic Low Back Pain: A Placebo-Controlled, Randomized Study

(2016) C Cloutier et al.   Pain Research & Management

Practical Considerations for the Use of Tapentadol Prolonged Release for the Management of Severe Chronic Pain

(2015) Manuel J. Sánchez del Águila et al.   CLINICAL THERAPEUTICS

The global burden of low back pain: estimates from the Global Burden of Disease 2010 study

(2014) Damian Hoy et al.   ANNALS OF THE RHEUMATIC DISEASES

Tapentadol potentiates descending pain inhibition in chronic pain patients with diabetic polyneuropathy

(2014) M. Niesters et al.   BRITISH JOURNAL OF ANAESTHESIA

Ready Conversion of Patients with Well-Controlled, Moderate to Severe, Chronic Malignant Tumor–related Pain on Other Opioids to Tapentadol Extended Release

(2014) Keiichiro Imanaka et al.   CLINICAL DRUG INVESTIGATION

The Mu-Opioid Receptor Agonist/Noradrenaline Reuptake Inhibition (MOR–NRI) Concept in Analgesia: The Case of Tapentadol

(2014) Thomas M. Tzschentke et al.   CNS DRUGS

A Randomized Withdrawal, Placebo-Controlled Study Evaluating the Efficacy and Tolerability of Tapentadol Extended Release in Patients With Chronic Painful Diabetic Peripheral Neuropathy

(2014) Aaron I. Vinik et al.   DIABETES CARE

Lack of synergistic interaction between the two mechanisms of action of tapentadol in gastrointestinal transit

(2014) A. Cowan et al.   EUROPEAN JOURNAL OF PAIN

Tapentadol Prolonged Release Versus Strong Opioids for Severe, Chronic Low Back Pain: Results of an Open-Label, Phase 3b Study

(2013) Rafael Gálvez et al.   ADVANCES IN THERAPY

Effectiveness and Tolerability of Tapentadol Prolonged Release Compared With Prior Opioid Therapy for the Management of Severe, Chronic Osteoarthritis Pain

(2013) Ilona Steigerwald et al.   CLINICAL DRUG INVESTIGATION

Efficacy and safety of oral tapentadol extended release in Japanese and Korean patients with moderate to severe, chronic malignant tumor-related pain

(2013) Keiichiro Imanaka et al.   CURRENT MEDICAL RESEARCH AND OPINION

What Is the Evidence that Neuropathic Pain Is Present in Chronic Low Back Pain and Soft Tissue Syndromes? An Evidence-Based Structured Review

(2013) David A. Fishbain et al.   PAIN MEDICINE

Effectiveness and safety of tapentadol prolonged release for severe, chronic low back pain with or without a neuropathic pain component: results of an open-label, phase 3b study

(2012) Ilona Steigerwald et al.   CURRENT MEDICAL RESEARCH AND OPINION

Synergistic Interaction between the Two Mechanisms of Action of Tapentadol in Analgesia

(2011) W. Schroder et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Efficacy and safety of tapentadol prolonged release for chronic osteoarthritis pain and low back pain

(2010) Bernd Lange et al.   ADVANCES IN THERAPY

Efficacy and Safety of Tapentadol Extended Release Compared with Oxycodone Controlled Release for the Management of Moderate to Severe Chronic Pain Related to Osteoarthritis of the Knee

(2010) Marc Afilalo et al.   CLINICAL DRUG INVESTIGATION

Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: results of a randomized-withdrawal, placebo-controlled trial

(2010) Sherwyn Schwartz et al.   CURRENT MEDICAL RESEARCH AND OPINION

Efficacy and safety of tapentadol extended release for the management of chronic low back pain: results of a prospective, randomized, double-blind, placebo- and active-controlled Phase III study

(2010) Robert Buynak et al.   EXPERT OPINION ON PHARMACOTHERAPY

Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment

(2010) Ralf Baron et al.   LANCET NEUROLOGY

Recommendations for the Pharmacological Management of Neuropathic Pain: An Overview and Literature Update

(2010) Robert H. Dworkin et al.   MAYO CLINIC PROCEEDINGS

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

(2009) Michael Costigan et al.   Annual Review of Neuroscience

Modelling the prevalence and cost of back pain with neuropathic components in the general population

(2009) Carsten O. Schmidt et al.   EUROPEAN JOURNAL OF PAIN

Nausea and Vomiting Side Effects with Opioid Analgesics during Treatment of Chronic Pain: Mechanisms, Implications, and Management Options

(2009) Frank Porreca et al.   PAIN MEDICINE

Assessment and diagnosis of neuropathic pain

(2009) Ralf Baron et al.   Current Opinion in Supportive and Palliative Care

Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate-to-severe noncancer pain

(2008) K. Simpson et al.   CURRENT MEDICAL RESEARCH AND OPINION

Prolonged-release oxycodone enhances the effects of existing gabapentin therapy in painful diabetic neuropathy patients

(2008) Magdi Hanna et al.   EUROPEAN JOURNAL OF PAIN

Analgesic Efficacy and Safety of Oxycodone in Combination With Naloxone as Prolonged Release Tablets in Patients With Moderate to Severe Chronic Pain

(2008) Dana Vondrackova et al.   JOURNAL OF PAIN

The Prevalence, Severity, and Impact of Opioid-Induced Bowel Dysfunction: Results of a US and European Patient Survey (PROBE 1)

(2008) Timothy J. Bell et al.   PAIN MEDICINE

Prevalence of chronic pain with neuropathic characteristics in the general population

(2007) Didier Bouhassira et al.   PAIN

Points to consider on switching between superiority and non-inferiority

(2002)   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY