Brain regulation of energy balance and body weight

Melanocortin 4 Receptors Reciprocally Regulate Sympathetic and Parasympathetic Preganglionic Neurons

(2013) Jong-Woo Sohn et al.   CELL

Arcuate NPY Controls Sympathetic Output and BAT Function via a Relay of Tyrosine Hydroxylase Neurons in the PVN

(2013) Yan-Chuan Shi et al.   Cell Metabolism

Tanycytic VEGF-A Boosts Blood-Hypothalamus Barrier Plasticity and Access of Metabolic Signals to the Arcuate Nucleus in Response to Fasting

(2013) Fanny Langlet et al.   Cell Metabolism

Reversal of Diet-Induced Obesity Increases Insulin Transport into Cerebrospinal Fluid and Restores Sensitivity to the Anorexic Action of Central Insulin in Male Rats

(2013) Denovan P. Begg et al.   ENDOCRINOLOGY

Adaptive thermogenesis in adipocytes: Is beige the new brown?

(2013) J. Wu et al.   GENES & DEVELOPMENT

 2 Adrenergic Receptor-Mediated Inhibition of Thermogenesis

(2013) C. J. Madden et al.   JOURNAL OF NEUROSCIENCE

Fgf10-Expressing Tanycytes Add New Neurons to the Appetite/Energy-Balance Regulating Centers of the Postnatal and Adult Hypothalamus

(2013) N. Haan et al.   JOURNAL OF NEUROSCIENCE

Acute and Long-Term Suppression of Feeding Behavior by POMC Neurons in the Brainstem and Hypothalamus, Respectively

(2013) C. Zhan et al.   JOURNAL OF NEUROSCIENCE

Insulin induces long-term depression of ventral tegmental area dopamine neurons via endocannabinoids

(2013) Gwenaël Labouèbe et al.   NATURE NEUROSCIENCE

Integration of sensory information via central thermoregulatory leptin targets

(2013) Kavon Rezai-Zadeh et al.   PHYSIOLOGY & BEHAVIOR

Behavioral responses to orexin, orexin receptor gene expression, and spontaneous physical activity contribute to individual sensitivity to obesity

(2012) Claudio E. Perez-Leighton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Thyrotropin-releasing hormone-containing axons innervate histaminergic neurons in the tuberomammillary nucleus

(2012) Anna Sárvári et al.   BRAIN RESEARCH

GABAergic RIP-Cre Neurons in the Arcuate Nucleus Selectively Regulate Energy Expenditure

(2012) Dong Kong et al.   CELL

BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

(2012) Andrew J. Whittle et al.   CELL

FoxO1 Target Gpr17 Activates AgRP Neurons to Regulate Food Intake

(2012) Hongxia Ren et al.   CELL

Hepatic Glucokinase Modulates Obesity Predisposition by Regulating BAT Thermogenesis via Neural Signals

(2012) Sohei Tsukita et al.   Cell Metabolism

Loss of Autophagy in Pro-opiomelanocortin Neurons Perturbs Axon Growth and Causes Metabolic Dysregulation

(2012) Bérengère Coupé et al.   Cell Metabolism

Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines

(2012) D. Lanfray et al.   DIABETES

Inhibition of Hypothalamic Inflammation Reverses Diet-Induced Insulin Resistance in the Liver

(2012) M. Milanski et al.   DIABETES

Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling

(2012) S. H. Lockie et al.   DIABETES

Loss of autophagy in hypothalamic POMC neurons impairs lipolysis

(2012) Susmita Kaushik et al.   EMBO REPORTS

Apolipoprotein AIV Requires Cholecystokinin and Vagal Nerves to Suppress Food Intake

(2012) Chunmin C. Lo et al.   ENDOCRINOLOGY

Role of Hypothalamic Proopiomelanocortin Neuron Autophagy in the Control of Appetite and Leptin Response

(2012) Wenying Quan et al.   ENDOCRINOLOGY

Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice

(2012) Pierre Cardinal et al.   ENDOCRINOLOGY

Fibroblast Growth Factor-19 Action in the Brain Reduces Food Intake and Body Weight and Improves Glucose Tolerance in Male Rats

(2012) Karen K. Ryan et al.   ENDOCRINOLOGY

Obesity and Appetite Control

(2012) Keisuke Suzuki et al.   Experimental Diabetes Research

Leptin regulates glutamate and glucose transporters in hypothalamic astrocytes

(2012) Esther Fuente-Martín et al.   JOURNAL OF CLINICAL INVESTIGATION

Human SH2B1 mutations are associated with maladaptive behaviors and obesity

(2012) Michael E. Doche et al.   JOURNAL OF CLINICAL INVESTIGATION

Efferent projections of neuropeptide Y-expressing neurons of the dorsomedial hypothalamus in chronic hyperphagic models

(2012) Shin J. Lee et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Regional astrogliosis in the mouse hypothalamus in response to obesity

(2012) Laura B. Buckman et al.   JOURNAL OF COMPARATIVE NEUROLOGY

β1 Adrenergic receptor is key to cold- and diet-induced thermogenesis in mice

(2012) Cintia B Ueta et al.   JOURNAL OF ENDOCRINOLOGY

Roles of Oxytocin Neurones in the Control of Stress, Energy Metabolism, and Social Behaviour

(2012) T. Onaka et al.   JOURNAL OF NEUROENDOCRINOLOGY

Serotonin Activates Catecholamine Neurons in the Solitary Tract Nucleus by Increasing Spontaneous Glutamate Inputs

(2012) R. J. Cui et al.   JOURNAL OF NEUROSCIENCE

Thyrotropin-Releasing Hormone (TRH) Inhibits Melanin-Concentrating Hormone Neurons: Implications for TRH-Mediated Anorexic and Arousal Actions

(2012) X. Zhang et al.   JOURNAL OF NEUROSCIENCE

Inactivation of Socs3 in the Hypothalamus Enhances the Hindbrain Response to Endogenous Satiety Signals via Oxytocin Signaling

(2012) V. Matarazzo et al.   JOURNAL OF NEUROSCIENCE

Deciphering a neuronal circuit that mediates appetite

(2012) Qi Wu et al.   NATURE

Deconstruction of a neural circuit for hunger

(2012) Deniz Atasoy et al.   NATURE

IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes

(2012) Juxue Li et al.   NATURE CELL BIOLOGY

Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin

(2012) Guey-Ying Liao et al.   NATURE MEDICINE

Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche

(2012) Daniel A Lee et al.   NATURE NEUROSCIENCE

Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling

(2012) Hu Huang et al.   NATURE NEUROSCIENCE

Rapamycin Ameliorates Age-Dependent Obesity Associated with Increased mTOR Signaling in Hypothalamic POMC Neurons

(2012) Shi-Bing Yang et al.   NEURON

Activation of VTA GABA Neurons Disrupts Reward Consumption

(2012) Ruud van Zessen et al.   NEURON

Fasting Activation of AgRP Neurons Requires NMDA Receptors and Involves Spinogenesis and Increased Excitatory Tone

(2012) Tiemin Liu et al.   NEURON

Dorsomedial hypothalamic NPY and energy balance control

(2012) Sheng Bi et al.   NEUROPEPTIDES

Loss of histaminergic modulation of thermoregulation and energy homeostasis in obese mice

(2012) J. Sethi et al.   NEUROSCIENCE

Cholinergic modulation of food and drug satiety and withdrawal

(2012) Nicole M. Avena et al.   PHYSIOLOGY & BEHAVIOR

Ablation of Sim1 Neurons Causes Obesity through Hyperphagia and Reduced Energy Expenditure

(2012) Dong Xi et al.   PLoS One

Y1 and Y5 Receptors Are Both Required for the Regulation of Food Intake and Energy Homeostasis in Mice

(2012) Amy D. Nguyen et al.   PLoS One

An Obligate Role of Oxytocin Neurons in Diet Induced Energy Expenditure

(2012) Zhaofei Wu et al.   PLoS One

Duodenal Lipid Sensing Activates Vagal Afferents to Regulate Non-Shivering Brown Fat Thermogenesis in Rats

(2012) Clémence Blouet et al.   PLoS One

Acute selective ablation of rat insulin promoter-expressing (RIPHER) neurons defines their orexigenic nature

(2012) E. Rother et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus

(2012) F. D. Jeanneteau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The neurobiology of food intake in an obesogenic environment

(2012) Hans-Rudolf Berthoud   PROCEEDINGS OF THE NUTRITION SOCIETY

Apolipoprotein A-IV regulates chylomicron metabolism–mechanism and function

(2011) Alison B. Kohan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Evidence for the role of hindbrain orexin-1 receptors in the control of meal size

(2011) Eric M. Parise et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The lighter side of BDNF

(2011) Emily E. Noble et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells

(2011) Sabrina Prudente et al.   ATHEROSCLEROSIS

Hunger States Switch a Flip-Flop Memory Circuit via a Synaptic AMPK-Dependent Positive Feedback Loop

(2011) Yunlei Yang et al.   CELL

Knockdown of NPY Expression in the Dorsomedial Hypothalamus Promotes Development of Brown Adipocytes and Prevents Diet-Induced Obesity

(2011) Pei-Ting Chao et al.   Cell Metabolism

Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance

(2011) Susmita Kaushik et al.   Cell Metabolism

White to Brown Fat Phenotypic Switch Induced by Genetic and Environmental Activation of a Hypothalamic-Adipocyte Axis

(2011) Lei Cao et al.   Cell Metabolism

Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction

(2011) Yong Xu et al.   Cell Metabolism

Intracellular Signals Mediating the Food Intake-Suppressive Effects of Hindbrain Glucagon-like Peptide-1 Receptor Activation

(2011) Matthew R. Hayes et al.   Cell Metabolism

SIRT1 Deacetylase in SF1 Neurons Protects against Metabolic Imbalance

(2011) Giorgio Ramadori et al.   Cell Metabolism

Leptin Action via Neurotensin Neurons Controls Orexin, the Mesolimbic Dopamine System and Energy Balance

(2011) Gina M. Leinninger et al.   Cell Metabolism

Melanocortin-4 Receptors Expressed by Cholinergic Neurons Regulate Energy Balance and Glucose Homeostasis

(2011) Jari Rossi et al.   Cell Metabolism

Metabolic and hedonic drives in the neural control of appetite: who is the boss?

(2011) Hans-Rudolf Berthoud   CURRENT OPINION IN NEUROBIOLOGY

CCK Stimulation of GLP-1 Neurons Involves α 1 -Adrenoceptor–Mediated Increase in Glutamatergic Synaptic Inputs

(2011) Kazunari Hisadome et al.   DIABETES

Deletion ofLkb1in Pro-Opiomelanocortin Neurons Impairs Peripheral Glucose Homeostasis in Mice

(2011) Marc Claret et al.   DIABETES

Association of genetic variants for susceptibility to obesity with type 2 diabetes in Japanese individuals

(2011) F. Takeuchi et al.   DIABETOLOGIA

Type 2 Corticotropin-Releasing Factor Receptor in the Ventromedial Nucleus of Hypothalamus Is Critical in Regulating Feeding and Lipid Metabolism in White Adipose Tissue

(2011) Hongxia Chao et al.   ENDOCRINOLOGY

GLP-1 Neurons in the Nucleus of the Solitary Tract Project Directly to the Ventral Tegmental Area and Nucleus Accumbens to Control for Food Intake

(2011) Amber L. Alhadeff et al.   ENDOCRINOLOGY

Implication of European-derived adiposity loci in African Americans

(2011) J M Hester et al.   INTERNATIONAL JOURNAL OF OBESITY

Importance of reward and prefrontal circuitry in hunger and satiety: Prader–Willi syndrome vs simple obesity

(2011) L M Holsen et al.   INTERNATIONAL JOURNAL OF OBESITY

Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice

(2011) Michael M. Scott et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

(2011) Michael J. Krashes et al.   JOURNAL OF CLINICAL INVESTIGATION

Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice

(2011) David E.G. McNay et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area

(2011) Kikuko Hotta et al.   JOURNAL OF HUMAN GENETICS

Leptin Action in the Dorsomedial Hypothalamus Increases Sympathetic Tone to Brown Adipose Tissue in Spite of Systemic Leptin Resistance

(2011) P. J. Enriori et al.   JOURNAL OF NEUROSCIENCE

Hyperphagia and Increased Fat Accumulation in Two Models of Chronic CNS Glucagon-Like Peptide-1 Loss of Function

(2011) J. G. Barrera et al.   JOURNAL OF NEUROSCIENCE

Leptin-Receptor-Expressing Neurons in the Dorsomedial Hypothalamus and Median Preoptic Area Regulate Sympathetic Brown Adipose Tissue Circuits

(2011) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Ghrelin Inhibits Visceral Afferent Activation of Catecholamine Neurons in the Solitary Tract Nucleus

(2011) R. J. Cui et al.   JOURNAL OF NEUROSCIENCE

Glucagon-Like Peptide 1 Receptors in Nucleus Accumbens Affect Food Intake

(2011) A. M. Dossat et al.   JOURNAL OF NEUROSCIENCE

An Orexinergic Projection from Perifornical Hypothalamus to Raphe Pallidus Increases Rat Brown Adipose Tissue Thermogenesis

(2011) D. Tupone et al.   JOURNAL OF NEUROSCIENCE

The role of the endocannabinoid system in the neuroendocrine regulation of energy balance

(2011) Francisco Javier Bermudez-Silva et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Weighing in the Role of BDNF in the Central Control of Eating Behavior

(2011) Joshua Cordeira et al.   MOLECULAR NEUROBIOLOGY

Peroxisome proliferation–associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity

(2011) Sabrina Diano et al.   NATURE MEDICINE

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

(2011) Yexica Aponte et al.   NATURE NEUROSCIENCE

Serotonin 2C Receptor Activates a Distinct Population of Arcuate Pro-opiomelanocortin Neurons via TRPC Channels

(2011) Jong-Woo Sohn et al.   NEURON

Neuropeptide Exocytosis Involving Synaptotagmin-4 and Oxytocin in Hypothalamic Programming of Body Weight and Energy Balance

(2011) Guo Zhang et al.   NEURON

Reward Mechanisms in Obesity: New Insights and Future Directions

(2011) Paul J. Kenny   NEURON

Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons

(2011) Linh Vong et al.   NEURON

The role of the gut/brain axis in modulating food intake

(2011) Amir H. Sam et al.   NEUROPHARMACOLOGY

Chronic Loss of Melanin-Concentrating Hormone Affects Motivational Aspects of Feeding in the Rat

(2011) Joram D. Mul et al.   PLoS One

Genome-Wide Population-Based Association Study of Extremely Overweight Young Adults – The GOYA Study

(2011) Lavinia Paternoster et al.   PLoS One

Studies of Metabolic Phenotypic Correlates of 15 Obesity Associated Gene Variants

(2011) Camilla Helene Sandholt et al.   PLoS One

Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus

(2011) K. W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System

(2011) Qiang Liu et al.   PLOS BIOLOGY

Hypoxia-Inducible Factor Directs POMC Gene to Mediate Hypothalamic Glucose Sensing and Energy Balance Regulation

(2011) Hai Zhang et al.   PLOS BIOLOGY

Evaluation of Genetic Susceptibility Loci for Obesity in Chinese Women

(2010) Jiajun Shi et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Chronic administration of brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reverses obesity induced by high-fat diet

(2010) ChuanFeng Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Inhibition of brown adipose tissue thermogenesis by neurons in the ventrolateral medulla and in the nucleus tractus solitarius

(2010) Wei-Hua Cao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

A potential role for hypothalamomedullary POMC projections in leptin-induced suppression of food intake

(2010) Huiyuan Zheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Ascending projections from the caudal visceral nucleus of the solitary tract to brain regions involved in food intake and energy expenditure

(2010) Linda Rinaman   BRAIN RESEARCH

Endogenous Leptin Signaling in the Caudal Nucleus Tractus Solitarius and Area Postrema Is Required for Energy Balance Regulation

(2010) Matthew R. Hayes et al.   Cell Metabolism

Leptin Directly Depolarizes Preproglucagon Neurons in the Nucleus Tractus Solitarius

(2010) Kazunari Hisadome et al.   DIABETES

Hypothalamic integration of portal glucose signals and control of food intake and insulin sensitivity

(2010) F. Delaere et al.   DIABETES & METABOLISM

Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA

(2010) C Holzapfel et al.   INTERNATIONAL JOURNAL OF OBESITY

Implication of Genetic Variants NearNEGR1,SEC16B,TMEM18,ETV5/DGKG,GNPDA2,LIN7C/BDNF,MTCH2,BCDIN3D/FAIM2,SH2B1,FTO,MC4R, andKCTD15with Obesity and Type 2 Diabetes in 7705 Chinese

(2010) Maggie C. Y. Ng et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Long-term Infusion of Brain-Derived Neurotrophic Factor Reduces Food Intake and Body Weight via a Corticotrophin-Releasing Hormone Pathway in the Paraventricular Nucleus of the Hypothalamus

(2010) M. Toriya et al.   JOURNAL OF NEUROENDOCRINOLOGY

Postnatal Sim1 Deficiency Causes Hyperphagic Obesity and Reduced Mc4r and Oxytocin Expression

(2010) K. P. Tolson et al.   JOURNAL OF NEUROSCIENCE

Leptin Excites Proopiomelanocortin Neurons via Activation of TRPC Channels

(2010) J. Qiu et al.   JOURNAL OF NEUROSCIENCE

Segregation of Acute Leptin and Insulin Effects in Distinct Populations of Arcuate Proopiomelanocortin Neurons

(2010) K. W. Williams et al.   JOURNAL OF NEUROSCIENCE

De Novo Neurogenesis in Adult Hypothalamus as a Compensatory Mechanism to Regulate Energy Balance

(2010) A. A. Pierce et al.   JOURNAL OF NEUROSCIENCE

Regulation of Thyrotropin-Releasing Hormone-Expressing Neurons in Paraventricular Nucleus of the Hypothalamus by Signals of Adiposity

(2010) Masoud Ghamari-Langroudi et al.   MOLECULAR ENDOCRINOLOGY

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

(2010) Miguel López et al.   NATURE MEDICINE

5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver

(2010) Yong Xu et al.   NATURE NEUROSCIENCE

MC4R Variant Is Associated With BMI but Not Response to Resistance Training in Young Females

(2010) Funda E. Orkunoglu-Suer et al.   Obesity

Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity

(2010) T. L. Horvath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference

(2009) Florianne Bauer et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Recent advances in understanding leptin signaling and leptin resistance

(2009) David L. Morris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hindbrain leptin receptor stimulation enhances the anorexic response to cholecystokinin

(2009) Diana L. Williams et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Neurons in the paraventricular nucleus of the hypothalamus inhibit sympathetic outflow to brown adipose tissue

(2009) C. J. Madden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Loss of GABAergic Signaling by AgRP Neurons to the Parabrachial Nucleus Leads to Starvation

(2009) Qi Wu et al.   CELL

Critical Role for Hypothalamic mTOR Activity in Energy Balance

(2009) Hiroyuki Mori et al.   Cell Metabolism

Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons

(2009) Hind Al-Qassab et al.   Cell Metabolism

Nesfatin-1-Regulated Oxytocinergic Signaling in the Paraventricular Nucleus Causes Anorexia through a Leptin-Independent Melanocortin Pathway

(2009) Yuko Maejima et al.   Cell Metabolism

Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance

(2009) Lale Ozcan et al.   Cell Metabolism

Leptin Acts via Leptin Receptor-Expressing Lateral Hypothalamic Neurons to Modulate the Mesolimbic Dopamine System and Suppress Feeding

(2009) Gina M. Leinninger et al.   Cell Metabolism

Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden

(2009) Frida Renström et al.   HUMAN MOLECULAR GENETICS

Paraventricular hypothalamic nucleus: Axonal projections to the brainstem

(2009) Joel C. Geerling et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Role of Dorsomedial Hypothalamic Neuropeptide Y in Modulating Food Intake and Energy Balance

(2009) L. Yang et al.   JOURNAL OF NEUROSCIENCE

Thyrotropin-Releasing Hormone Increases Behavioral Arousal through Modulation of Hypocretin/Orexin Neurons

(2009) J. Hara et al.   JOURNAL OF NEUROSCIENCE

PACAP Neurons in the Hypothalamic Ventromedial Nucleus Are Targets of Central Leptin Signaling

(2009) Z. Hawke et al.   JOURNAL OF NEUROSCIENCE

Excitation of Histaminergic Tuberomamillary Neurons by Thyrotropin-Releasing Hormone

(2009) R. Parmentier et al.   JOURNAL OF NEUROSCIENCE

Parallel Preoptic Pathways for Thermoregulation

(2009) K. Yoshida et al.   JOURNAL OF NEUROSCIENCE

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

Stimulation of orexin/hypocretin neurones by thyrotropin-releasing hormone

(2009) J. Antonio González et al.   JOURNAL OF PHYSIOLOGY-LONDON

Large, rare chromosomal deletions associated with severe early-onset obesity

(2009) Elena G. Bochukova et al.   NATURE

Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study

(2009) Axel Haupt et al.   Obesity

The melanin-concentrating hormone system modulates cocaine reward

(2009) S. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melanocortin-4 receptor mRNA expressed in sympathetic outflow neurons to brown adipose tissue: neuroanatomical and functional evidence

(2008) C. Kay Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance

(2008) Kristin A. Anderson et al.   Cell Metabolism

Ghrelin Modulates Brain Activity in Areas that Control Appetitive Behavior

(2008) Saima Malik et al.   Cell Metabolism

Endogenous prolactin-releasing peptide regulates food intake in rodents

(2008) Yuki Takayanagi et al.   JOURNAL OF CLINICAL INVESTIGATION

Presynaptic Melanocortin-4 Receptors on Vagal Afferent Fibers Modulate the Excitability of Rat Nucleus Tractus Solitarius Neurons

(2008) S. Wan et al.   JOURNAL OF NEUROSCIENCE

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

(2008) Zane B. Andrews et al.   NATURE

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

(2008) Qingchun Tong et al.   NATURE NEUROSCIENCE

5-HT2CRs Expressed by Pro-Opiomelanocortin Neurons Regulate Energy Homeostasis

(2008) Yong Xu et al.   NEURON

Neuroendocrine control of food intake

(2008) Elena Valassi et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Characterization of apolipoprotein A-IV in brain areas involved in energy homeostasis

(2008) Ling Shen et al.   PHYSIOLOGY & BEHAVIOR

Opioid reward ‘liking’ and ‘wanting’ in the nucleus accumbens

(2008) Susana Peciña   PHYSIOLOGY & BEHAVIOR

The Role of the Thyrotropin-Releasing Hormone (TRH) Neuron as a Metabolic Sensor

(2008) Anthony N. Hollenberg   THYROID

The hypothalamic-pituitary-adrenal-axis in the regulation of energy balance

(2007) Arie G. Nieuwenhuizen et al.   PHYSIOLOGY & BEHAVIOR