The lighter side of BDNF

Chronic administration of brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reverses obesity induced by high-fat diet

(2010) ChuanFeng Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Role of oxidative/nitrosative stress-mediated Bcl-2 regulation in apoptosis and malignant transformation

(2010) Neelam Azad et al.   Annals of the New York Academy of Sciences

Acute stress alters transcript expression pattern and reduces processing of proBDNF to mature BDNF in Dicentrarchus labrax

(2010) Chiara Tognoli et al.   BMC NEUROSCIENCE

BDNF Val66Met polymorphism, energy intake and BMI: a follow-up study in schoolchildren at risk of eating disorders

(2010) Victoria Arija et al.   BMC PUBLIC HEALTH

Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditure

(2010) ChuanFeng Wang et al.   BRAIN RESEARCH

Environmental and Genetic Activation of a Brain-Adipocyte BDNF/Leptin Axis Causes Cancer Remission and Inhibition

(2010) Lei Cao et al.   CELL

Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance

(2010) D. W. Porter et al.   DIABETES OBESITY & METABOLISM

Increased Food Intake Leads to Obesity and Insulin Resistance in the Tg2576 Alzheimer’s Disease Mouse Model

(2010) Motoyuki Kohjima et al.   ENDOCRINOLOGY

Green tea averts age-dependent decline of hippocampal signaling systems related to antioxidant defenses and survival

(2010) Marco Assunção et al.   FREE RADICAL BIOLOGY AND MEDICINE

Diminished diet-induced hyperglycemia and dyslipidemia and enhanced expression of PPARα and FGF21 in mice with hepatic ablation of brain-derived neurotropic factor

(2010) Sarah Teillon et al.   JOURNAL OF ENDOCRINOLOGY

Long-term Infusion of Brain-Derived Neurotrophic Factor Reduces Food Intake and Body Weight via a Corticotrophin-Releasing Hormone Pathway in the Paraventricular Nucleus of the Hypothalamus

(2010) M. Toriya et al.   JOURNAL OF NEUROENDOCRINOLOGY

Chronic Intermittent Hypoxia Induces NMDA Receptor-Dependent Plasticity and Suppresses Nitric Oxide Signaling in the Mouse Hypothalamic Paraventricular Nucleus

(2010) C. G. Coleman et al.   JOURNAL OF NEUROSCIENCE

Brain-Derived Neurotrophic Factor Regulates Hedonic Feeding by Acting on the Mesolimbic Dopamine System

(2010) J. W. Cordeira et al.   JOURNAL OF NEUROSCIENCE

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring

(2010) Yusuke Tozuka et al.   NEUROCHEMISTRY INTERNATIONAL

Exercise and time-dependent benefits to learning and memory

(2010) N.C. Berchtold et al.   NEUROSCIENCE

Cyclophosphamide promotes cell survival via activation of intracellular signaling in cultured cortical neurons

(2010) Hiromi Kitazawa et al.   NEUROSCIENCE LETTERS

A high-fat diet impairs neurogenesis: Involvement of lipid peroxidation and brain-derived neurotrophic factor

(2010) Hee Ra Park et al.   NEUROSCIENCE LETTERS

Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: Role of hippocampus

(2010) Jayanthi Maniam et al.   PSYCHONEUROENDOCRINOLOGY

Exercise improves cognition and hippocampal plasticity in APOE ε4 mice

(2009) Kathryn Nichol et al.   Alzheimers & Dementia

Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models—association with liver and adipose tissue effects

(2009) Jing Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Effects of BDNF, T3, and corticosterone on expression of the hypothalamic obesity gene network in vivo and in vitro

(2009) Mardi S. Byerly et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Melanocortin activity in the amygdala controls appetite for dietary fat

(2009) Stéphane Boghossian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Endurance training enhances BDNF release from the human brain

(2009) Thomas Seifert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase

(2009) V. B. Matthews et al.   DIABETOLOGIA

Brain-Derived Neurotrophic Factor/Tropomyosin-Related Kinase Receptor Type B Signaling Is a Downstream Effector of the Brainstem Melanocortin System in Food Intake Control

(2009) Bruno Bariohay et al.   ENDOCRINOLOGY

Diet-induced obesity in female mice leads to peroxidized lipid accumulations and impairment of hippocampal neurogenesis during the early life of their offspring

(2009) Yusuke Tozuka et al.   FASEB JOURNAL

Exercise enhances hippocampal-dependent learning in the rat: Evidence for a BDNF-related mechanism

(2009) Éadaoin W. Griffin et al.   HIPPOCAMPUS

Running exercise-induced up-regulation of hippocampal brain-derived neurotrophic factor is CREB-dependent

(2009) Michael J. Chen et al.   HIPPOCAMPUS

Extremely Different Behaviours in High and Low Body Weight Lines of Chicken are Associated with Differential Expression of Genes Involved in Neuronal Plasticity

(2009) S. Ka et al.   JOURNAL OF NEUROENDOCRINOLOGY

Molecular therapy of obesity and diabetes by a physiological autoregulatory approach

(2009) Lei Cao et al.   NATURE MEDICINE

Energy-restricted pair-feeding normalizes low levels of brain-derived neurotrophic factor/tyrosine kinase B mRNA expression in the hippocampus, but not ventromedial hypothalamic nucleus, in diet-induced obese mice

(2009) Y. Yu et al.   NEUROSCIENCE

Interactive effect of excitotoxic injury and dietary restriction on neurogenesis and neurotrophic factors in adult male rat brain

(2009) Sushil Kumar et al.   NEUROSCIENCE RESEARCH

High-Fat Diet Induces Apoptosis of Hypothalamic Neurons

(2009) Juliana C. Moraes et al.   PLoS One

Plasticity of pre- and postsynaptic GABAB receptor function in the paraventricular nucleus in spontaneously hypertensive rats

(2008) De-Pei Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Intramuscular lipid oxidation and obesity

(2008) Joseph A. Houmard   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

BDNF-TrkB signaling interacts with the GABAergic system to inhibit rhythmic swallowing in the rat

(2008) Bruno Bariohay et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Brain-derived neurotrophic factor (BDNF) prevents the development of diabetes in prediabetic mice

(2008) Mitsugu YAMANAKA et al.   BIOMEDICAL RESEARCH-TOKYO

Serum brain-derived neurotrophic factor in patients with type 2 diabetes mellitus: Relationship to glucose metabolism and biomarkers of insulin resistance

(2008) Aya Fujinami et al.   CLINICAL BIOCHEMISTRY

Plasma brain-derived neurotrophic factor in women after bariatric surgery: a pilot study

(2008) Zaher O. Merhi et al.   FERTILITY AND STERILITY

Dopaminergic and brain-derived neurotrophic factor signalling in inbred mice exposed to a restricted feeding schedule

(2008) C. Gelegen et al.   GENES BRAIN AND BEHAVIOR

Altered morphology of hippocampal dentate granule cell presynaptic and postsynaptic terminals following conditional deletion of TrkB

(2008) Steve C. Danzer et al.   HIPPOCAMPUS

Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats

(2008) Alexis M. Stranahan et al.   HIPPOCAMPUS

Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation

(2008) Terry L. Davidson et al.   HIPPOCAMPUS

Single immobilization stress differentially alters the expression profile of transcripts of the brain-derived neurotrophic factor ( BDNF) gene and histone acetylation at its promoters in the rat hippocampus

(2008) Manabu Fuchikami et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Intermittent administration of brain-derived neurotrophic factor (BDNF) ameliorates glucose metabolism and prevents pancreatic exhaustion in diabetic mice

(2008) Mitsugu Yamanaka et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Maternal High-Fat Diet and Fetal Programming: Increased Proliferation of Hypothalamic Peptide-Producing Neurons That Increase Risk for Overeating and Obesity

(2008) G.-Q. Chang et al.   JOURNAL OF NEUROSCIENCE

Association of the BDNF Val66Met variation with obesity in women

(2008) Sigri Beckers et al.   MOLECULAR GENETICS AND METABOLISM

BDNF-induced synaptic delivery of AMPAR subunits is differentially dependent on NMDA receptors and requires ERK

(2008) Wei Li et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Biochemical markers in persons with preclinical familial Alzheimer disease

(2008) J. M. Ringman et al.   NEUROLOGY

Coordinate action of pre- and postsynaptic brain-derived neurotrophic factor is required for AMPAR trafficking and acquisition of in vitro classical conditioning

(2008) W. Li et al.   NEUROSCIENCE

Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

(2008) Joan C. Han et al.   NEW ENGLAND JOURNAL OF MEDICINE

Appetite Enhancement and Weight Gain by Peripheral Administration of TrkB Agonists in Non-Human Primates

(2008) John C. Lin et al.   PLoS One

Low serum BDNF and food intake regulation: A possible new explanation of the pathophysiology of eating disorders

(2008) Satoshi Saito et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Brain-derived neurotrophic factor (BDNF) and set-shifting in currently ill and recovered anorexia nervosa (AN) patients

(2008) M. Nakazato et al.   PSYCHOLOGICAL MEDICINE

Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines

(2008) J.-i. Tanaka et al.   SCIENCE

Adipose tissue and skeletal muscle plasticity modulates metabolic health

(2008) Jozef Ukropec et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

TrkB Agonists Ameliorate Obesity and Associated Metabolic Conditions in Mice

(2007) David Tsao et al.   ENDOCRINOLOGY

Neuroprotection by Imipramine against lipopolysaccharide-induced apoptosis in hippocampus-derived neural stem cells mediated by activation of BDNF and the MAPK pathway

(2007) Chi-Hsien Peng et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Repetitive induction of late-phase LTP produces long-lasting synaptic enhancement accompanied by synaptogenesis in cultured hippocampal slices

(2007) Keiko Tominaga-Yoshino et al.   HIPPOCAMPUS