Studies of Metabolic Phenotypic Correlates of 15 Obesity Associated Gene Variants

The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

(2010) Markus Sällman Almén et al.   BMC Medical Genetics

Combined Analyses of 20 Common Obesity Susceptibility Variants

(2010) C. H. Sandholt et al.   DIABETES

Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA

(2010) C Holzapfel et al.   INTERNATIONAL JOURNAL OF OBESITY

Implication of Genetic Variants NearNEGR1,SEC16B,TMEM18,ETV5/DGKG,GNPDA2,LIN7C/BDNF,MTCH2,BCDIN3D/FAIM2,SH2B1,FTO,MC4R, andKCTD15with Obesity and Type 2 Diabetes in 7705 Chinese

(2010) Maggie C. Y. Ng et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups

(2010) André Scherag et al.   PLoS Genetics

Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference

(2009) Florianne Bauer et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

SH2B1 Enhances Insulin Sensitivity by Both Stimulating the Insulin Receptor and Inhibiting Tyrosine Dephosphorylation of Insulin Receptor Substrate Proteins

(2009) D. L. Morris et al.   DIABETES

Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study

(2009) T. O. Kilpelainen et al.   HUMAN MOLECULAR GENETICS

Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden

(2009) Frida Renström et al.   HUMAN MOLECULAR GENETICS

Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure

(2009) S I I Kring et al.   INTERNATIONAL JOURNAL OF OBESITY

Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population

(2009) Kikuko Hotta et al.   JOURNAL OF HUMAN GENETICS

A supersized list of obesity genes

(2009) Marten Hofker et al.   NATURE GENETICS

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

(2009) David Meyre et al.   NATURE GENETICS

Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study

(2009) Axel Haupt et al.   Obesity

Variants Near MC4R Are Associated With Obesity and Influence Obesity-Related Quantitative Traits in a Population of Middle-Aged People: Studies of 14,940 Danes

(2008) D. P. Zobel et al.   DIABETES

Genome-wide association scans identified CTNNBL1 as a novel gene for obesity

(2008) Yong-Jun Liu et al.   HUMAN MOLECULAR GENETICS

Replication of the association of common rs9939609 variant of FTO with increased BMI in an Australian adult twin population but no evidence for gene by environment (G × E) interaction

(2008) B K Cornes et al.   INTERNATIONAL JOURNAL OF OBESITY

Common nonsynonymous variants in PCSK1 confer risk of obesity

(2008) Michael Benzinou et al.   NATURE GENETICS

Common variants near MC4R are associated with fat mass, weight and risk of obesity

(2008) Ruth J F Loos et al.   NATURE GENETICS

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Common genetic variation near MC4R is associated with waist circumference and insulin resistance

(2008) John C Chambers et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

Variants in the FTO gene are associated with common obesity in the Belgian population

(2007) Armand Peeters et al.   MOLECULAR GENETICS AND METABOLISM