Primary CD8+ T cells from elite suppressors effectively eliminate non-productively HIV-1 infected resting and activated CD4+ T cells

Comprehensive analysis of unique cases with extraordinary control over HIV replication

(2012) D. Mendoza et al.   BLOOD

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

(2012) Liang Shan et al.   IMMUNITY

Antiviral Inhibitory Capacity of CD8+ T cells Predicts the Rate of CD4+ T-Cell Decline in HIV-1 Infection

(2012) Hongbing Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Early Antigen Presentation of Protective HIV-1 KF11Gag and KK10Gag Epitopes from Incoming Viral Particles Facilitates Rapid Recognition of Infected Cells by Specific CD8+ T Cells

(2012) H. N. Kloverpris et al.   JOURNAL OF VIROLOGY

Inhibitory Potential of Subpopulations of CD8+ T Cells in HIV-1-Infected Elite Suppressors

(2012) R. W. Buckheit et al.   JOURNAL OF VIROLOGY

Directly Infected Resting CD4+T Cells Can Produce HIV Gag without Spreading Infection in a Model of HIV Latency

(2012) Matthew J. Pace et al.   PLoS Pathogens

Circulating Monocytes Are Not a Major Reservoir of HIV-1 in Elite Suppressors

(2011) A. M. Spivak et al.   JOURNAL OF VIROLOGY

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

CD4+ T cells from elite suppressors are more susceptible to HIV-1 but produce fewer virions than cells from chronic progressors

(2011) K. A. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The study of elite controllers: a pure academic exercise or a potential pathway to an HIV-1 vaccine?

(2011) Joel N Blankson   Current Opinion in HIV and AIDS

Functional Cure of SIVagm Infection in Rhesus Macaques Results in Complete Recovery of CD4+ T Cells and Is Reverted by CD8+ Cell Depletion

(2011) Ivona Pandrea et al.   PLoS Pathogens

Elite Suppressors Harbor Low Levels of Integrated HIV DNA and High Levels of 2-LTR Circular HIV DNA Compared to HIV+ Patients On and Off HAART

(2011) Erin H. Graf et al.   PLoS Pathogens

Infrequent Recovery of HIV from but Robust Exogenous Infection of Activated CD4+T Cells in HIV Elite Controllers

(2010) B. Julg et al.   CLINICAL INFECTIOUS DISEASES

HIV-1 Continues To Replicate and Evolve in Patients with Natural Control of HIV Infection

(2010) H. Mens et al.   JOURNAL OF VIROLOGY

Unstimulated Primary CD4+ T Cells from HIV-1-Positive Elite Suppressors Are Fully Susceptible to HIV-1 Entry and Productive Infection

(2010) S. A. Rabi et al.   JOURNAL OF VIROLOGY

Control of HIV-1 in Elite Suppressors despite Ongoing Replication and Evolution in Plasma Virus

(2010) K. A. O'Connell et al.   JOURNAL OF VIROLOGY

Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors

(2010) Maria Salgado et al.   Retrovirology

Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

(2010) Adam R. Hersperger et al.   PLoS Pathogens

The role of protective HCP5 and HLA-C associated polymorphisms in the control of HIV-1 replication in a subset of elite suppressors

(2009) Yefei Han et al.   AIDS

Spontaneous Control of Viral Replication during Primary HIV Infection: When Is “HIV Controller” Status Established?

(2009) Cécile Goujard et al.   CLINICAL INFECTIOUS DISEASES

Epidemiologic Characteristics and Natural History of HIV-1 Natural Viral Suppressors

(2009) Mohammad M Sajadi et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Heterogeneity in HIV Suppression by CD8 T Cells from HIV Controllers: Association with Gag-Specific CD8 T Cell Responses

(2009) A. Saez-Cirion et al.   JOURNAL OF IMMUNOLOGY

Persistent Low‐Level Viremia in HIV‐1 Elite Controllers and Relationship to Immunologic Parameters

(2009) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

The CXCR4-Tropic Human Immunodeficiency Virus Envelope Promotes More-Efficient Gene Delivery to Resting CD4+ T Cells than the Vesicular Stomatitis Virus Glycoprotein G Envelope

(2009) L. M. Agosto et al.   JOURNAL OF VIROLOGY

Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection

(2008) Daniëlle van Manen et al.   AIDS

Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control

(2008) A. L. Ferre et al.   BLOOD

A Comparison of Viral Loads between HIV‐1–Infected Elite Suppressors and Individuals Who Receive Suppressive Highly Active Antiretroviral Therapy

(2008) Jason B. Dinoso et al.   CLINICAL INFECTIOUS DISEASES

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY

Genetic and Immunologic Heterogeneity among Persons Who Control HIV Infection in the Absence of Therapy

(2008) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

Genomewide Association Study of an AIDS‐Nonprogression Cohort Emphasizes the Role Played byHLAGenes (ANRS Genomewide Association Study 02)

(2008) Sophie Limou et al.   JOURNAL OF INFECTIOUS DISEASES

HLA Class I-Restricted T-Cell Responses May Contribute to the Control of Human Immunodeficiency Virus Infection, but Such Responses Are Not Always Necessary for Long-Term Virus Control

(2008) B. Emu et al.   JOURNAL OF VIROLOGY

Evidence of CD8+ T-Cell-Mediated Selective Pressure on Human Immunodeficiency Virus Type 1 nef in HLA-B*57+ Elite Suppressors

(2008) J. R. Bailey et al.   JOURNAL OF VIROLOGY

Evidence for Persistent Low-Level Viremia in Individuals Who Control Human Immunodeficiency Virus in the Absence of Antiretroviral Therapy

(2008) H. Hatano et al.   JOURNAL OF VIROLOGY

HIV-1 Disease-Influencing Effects Associated with ZNRD1, HCP5 and HLA-C Alleles Are Attributable Mainly to Either HLA-A10 or HLA-B*57 Alleles

(2008) Gabriel Catano et al.   PLoS One

Distinct Genetic Loci Control Plasma HIV-RNA and Cellular HIV-DNA Levels in HIV-1 Infection: The ANRS Genome Wide Association 01 Study

(2008) Cyril Dalmasso et al.   PLoS One