A reciprocating twin-channel model for ABC transporters

Catalyst-like modulation of transition states for CFTR channel opening and closing: New stimulation strategy exploits nonequilibrium gating

(2014) László Csanády et al.   JOURNAL OF GENERAL PHYSIOLOGY

Olive-Oil-Derived Oleocanthal Enhances β-Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer’s Disease: In Vitro and in Vivo Studies

(2013) Alaa H. Abuznait et al.   ACS Chemical Neuroscience

Evolutionary relationships of ATP-Binding Cassette (ABC) uptake porters

(2013) Wei Hao Zheng et al.   BMC MICROBIOLOGY

Cystic Fibrosis Therapeutics

(2013) Lucas R. Hoffman et al.   CHEST

Molecular mechanism of the Escherichia coli maltose transporter

(2013) Jue Chen   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Deviant ATP-binding Site of the Multidrug Efflux Pump Pdr5 Plays an Active Role in the Transport Cycle

(2013) Christopher Furman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired mitochondrial energy production and ABC transporter function—A crucial interconnection in dementing proteopathies of the brain

(2013) Jens Pahnke et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Structure of a bacterial energy-coupling factor transporter

(2013) Tingliang Wang et al.   NATURE

Vx-770 potentiates CFTR function by promoting decoupling between the gating cycle and ATP hydrolysis cycle

(2013) Kang-Yang Jih et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two molybdate/tungstate ABC transporters that interact very differently with their substrate binding proteins

(2013) E. Vigonsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain

(2013) A. B. Ward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type I secretion systems – a story of appendices

(2013) Kerstin Kanonenberg et al.   RESEARCH IN MICROBIOLOGY

Decorating Proteins with “Sweets” Is a Flexible Matter

(2013) Zhiyi Wei et al.   STRUCTURE

Novel pharmacological strategies to treat cystic fibrosis

(2013) John W. Hanrahan et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A vitamin B12 transporter in Mycobacterium tuberculosis

(2013) K. Gopinath et al.   Open Biology

Role of ATP binding and hydrolysis in the gating of the cystic fibrosis transmembrane conductance regulator

(2012) Taras Gout   Annals of Thoracic Medicine

Substrate translocation and stimulated ATP hydrolysis of human ABC transporter MRP3 show positive cooperativity and are half-coupled

(2012) Patrick Seelheim et al.   BIOPHYSICAL CHEMISTRY

Co action of CFTR and AQP1 increases permeability of peritoneal epithelial cells on estrogen-induced ovarian hyper stimulation syndrome

(2012) Pei-Yin Jin et al.   BMC CELL BIOLOGY

Mechanism of the ABC transporter ATPase domains: catalytic models and the biochemical and biophysical record

(2012) Peter M. Jones et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Retinoid Binding Properties of Nucleotide Binding Domain 1 of the Stargardt Disease-associated ATP Binding Cassette (ABC) Transporter, ABCA4

(2012) Esther E. Biswas-Fiss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternating Access to the Transmembrane Domain of the ATP-binding Cassette Protein Cystic Fibrosis Transmembrane Conductance Regulator (ABCC7)

(2012) Wuyang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipofuscin andN-Retinylidene-N-Retinylethanolamine (A2E) Accumulate in Retinal Pigment Epithelium in Absence of Light Exposure

(2012) Nicholas P. Boyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Asymmetry in the Homodimeric ABC Transporter MsbA Recognized by a DARPin

(2012) Anshumali Mittal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amino acid transport in thermophiles: Characterization of an arginine-binding protein from Thermotoga maritima. 3. Conformational dynamics and stability

(2012) A. Ausili et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Role of the D-Loops in Allosteric Control of ATP Hydrolysis in an ABC Transporter

(2012) Peter M. Jones et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Discovery of an Auto-Regulation Mechanism for the Maltose ABC Transporter MalFGK2

(2012) Huan Bao et al.   PLoS One

Perspectives on the structure–function of ABC transporters: The Switch and Constant Contact Models

(2012) Anthony M. George et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

The role of ATP-binding cassette transporters in bacterial pathogenicity

(2012) Victoria G. Lewis et al.   PROTOPLASMA

ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer

(2012) Faraz Quazi et al.   Nature Communications

Conformational Analysis of Human ATP-binding Cassette Transporter ABCB1 in Lipid Nanodiscs and Inhibition by the Antibodies MRK16 and UIC2

(2011) Tasha K. Ritchie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutant cycles at CFTR’s non-canonical ATP-binding site support little interface separation during gating

(2011) Andras Szollosi et al.   JOURNAL OF GENERAL PHYSIOLOGY

Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7)

(2011) Yonghong Bai et al.   JOURNAL OF GENERAL PHYSIOLOGY

Type II ABC Permeases: Are They Really So Different?

(2011) Anthony M. George et al.   STRUCTURE

Classification of a Haemophilus influenzae ABC Transporter HI1470/71 through Its Cognate Molybdate Periplasmic Binding Protein, MolA

(2011) Leidamarie Tirado-Lee et al.   STRUCTURE

Apo and ligand-bound structures of ModA from the archaeonMethanosarcina acetivorans

(2010) Sum Chan et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Regulatory Insertion Removal Restores Maturation, Stability and Function of ΔF508 CFTR

(2010) Andrei A. Aleksandrov et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Dissection of Dual Pseudosymmetric Solute Translocation Pathways in Human P-Glycoprotein

(2010) Z. Parveen et al.   MOLECULAR PHARMACOLOGY

A distinct mechanism for the ABC transporter BtuCD–BtuF revealed by the dynamics of complex formation

(2010) Oded Lewinson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The ATP-binding cassette family: a structural perspective

(2009) Veronica Kos et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Distorted octahedral coordination of tungstate in a subfamily of specific binding proteins

(2009) Kaspar Hollenstein et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

State-dependent modulation of CFTR gating by pyrophosphate

(2009) Ming-Feng Tsai et al.   JOURNAL OF GENERAL PHYSIOLOGY

Membrane Porters of ATP-Binding Cassette Transport Systems Are Polyphyletic

(2009) Bin Wang et al.   JOURNAL OF MEMBRANE BIOLOGY

Amino acid transport in thermophiles: characterization of an arginine-binding protein in Thermotoga maritima

(2009) Matthew S. Luchansky et al.   Molecular BioSystems

ABC transporters: the power to change

(2009) Douglas C. Rees et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

ABC transporters: a riddle wrapped in a mystery inside an enigma

(2009) Peter M. Jones et al.   TRENDS IN BIOCHEMICAL SCIENCES

Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter

(2008) Isabelle J. Létourneau et al.   BIOCHEMICAL PHARMACOLOGY

Structural insights into ABC transporter mechanism

(2008) Michael L Oldham et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

AdcAII, A New Pneumococcal Zn-Binding Protein Homologous with ABC Transporters: Biochemical and Structural Analysis

(2008) Elodie Loisel et al.   JOURNAL OF MOLECULAR BIOLOGY

The Role of ATP Binding Cassette Transporters in Tissue Defense and Organ Regeneration

(2008) M. Huls et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems

(2008) A. L. Davidson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Structure and mechanism of ATP-binding cassette transporters

(2008) K. P Locher   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Opening of the ADP-bound active site in the ABC transporter ATPase dimer: Evidence for a constant contact, alternating sites model for the catalytic cycle

(2008) Peter M. Jones et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Crystal Structures and Mutational Analysis of the Arginine-, Lysine-, Histidine-binding Protein ArtJ from Geobacillus stearothermophilus. Implications for Interactions of ArtJ with its Cognate ATP-binding Cassette Transporter, Art(MP)2

(2007) Ardeschir Vahedi-Faridi et al.   JOURNAL OF MOLECULAR BIOLOGY