The utility of patient specific induced pluripotent stem cells for the modelling of Autistic Spectrum Disorders

Cytosystems dynamics in self-organization of tissue architecture

(2013) Yoshiki Sasai   NATURE

Activity-dependent neuronal signalling and autism spectrum disorder

(2013) Daniel H. Ebert et al.   NATURE

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

In utero exposure to valproic acid and autism — A current review of clinical and animal studies

(2013) Florence I. Roullet et al.   NEUROTOXICOLOGY AND TERATOLOGY

Robust Formation and Maintenance of Continuous Stratified Cortical Neuroepithelium by Laminin-Containing Matrix in Mouse ES Cell Culture

(2013) Makoto Nasu et al.   PLoS One

Modeling Brain Disease in a Dish: Really?

(2012) Maria C. Marchetto et al.   Cell Stem Cell

Genetic architecture in autism spectrum disorder

(2012) Bernie Devlin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Introduction to special issue on neuroimmunology in brain development and disease

(2012) A. Kimberley McAllister et al.   Developmental Neurobiology

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

(2012) Yichen Shi et al.   NATURE NEUROSCIENCE

Autism spectrum disorders

(2012) Sarah Nightingale   NATURE REVIEWS DRUG DISCOVERY

Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism

(2012) S. J. Baudouin et al.   SCIENCE

Pathways to Drug Development for Autism Spectrum Disorders

(2011) D R Hampson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Opportunities for Use of Human iPS Cells in Predictive Toxicology

(2011) B D Anson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Importance of Shank3 Protein in Regulating Metabotropic Glutamate Receptor 5 (mGluR5) Expression and Signaling at Synapses

(2011) Chiara Verpelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism

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A bioinformatic assay for pluripotency in human cells

(2011) Franz-Josef Müller et al.   NATURE METHODS

Generation of transgene-free human induced pluripotent stem cells with an excisable single polycistronic vector

(2011) Eirini P Papapetrou et al.   Nature Protocols

Toward Fulfilling the Promise of Molecular Medicine in Fragile X Syndrome

(2010) Dilja D. Krueger et al.   Annual Review of Medicine

Primary Cells and Stem Cells in Drug Discovery: Emerging Tools for High-Throughput Screening

(2010) Richard Eglen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Etiological heterogeneity in autism spectrum disorders: More than 100 genetic and genomic disorders and still counting

(2010) Catalina Betancur   BRAIN RESEARCH

Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds

(2010) Saiyong Zhu et al.   Cell Stem Cell

A Call to Standardize Teratoma Assays Used to Define Human Pluripotent Cell Lines

(2010) Franz-Josef Müller et al.   Cell Stem Cell

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Development of Defective and Persistent Sendai Virus Vector

(2010) Ken Nishimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conserved role of intragenic DNA methylation in regulating alternative promoters

(2010) Alika K. Maunakea et al.   NATURE

Ontogeny-recapitulating generation and tissue integration of ES cell–derived Purkinje cells

(2010) Keiko Muguruma et al.   NATURE NEUROSCIENCE

Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells

(2010) Trond Aasen et al.   Nature Protocols

Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report

(2010) Timothy Buie et al.   PEDIATRICS

Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders

(2009) Z. Ye et al.   BLOOD

A Topographic Study of Minicolumnar Core Width by Lamina Comparison between Autistic Subjects and Controls: Possible Minicolumnar Disruption due to an Anatomical Element In-Common to Multiple Laminae

(2009) Manuel F. Casanova et al.   BRAIN PATHOLOGY

The Postsynaptic Density Proteins Homer and Shank Form a Polymeric Network Structure

(2009) Mariko Kato Hayashi et al.   CELL

Broader Implications of Defining Standards for the Pluripotency of iPSCs

(2009) George Q. Daley et al.   Cell Stem Cell

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements

(2009) Alan Huett et al.   EXPERIMENTAL CELL RESEARCH

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells

(2009) Elayne M Chan et al.   NATURE BIOTECHNOLOGY

Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences

(2009) J. Yu et al.   SCIENCE

Guidelines and Techniques for the Generation of Induced Pluripotent Stem Cells

(2008) Nimet Maherali et al.   Cell Stem Cell

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell

Cerebellar Purkinje Cells are Reduced in a Subpopulation of Autistic Brains: A Stereological Experiment Using Calbindin-D28k

(2008) Elizabeth R. Whitney et al.   CEREBELLUM

Law should recognize value of interspecies embryos

(2008) Justin C. St John et al.   NATURE

Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

(2008) Trond Aasen et al.   NATURE BIOTECHNOLOGY

Removing Obstacles in Neuroscience Drug Discovery: The Future Path for Animal Models

(2008) Athina Markou et al.   NEUROPSYCHOPHARMACOLOGY

Reprogramming of murine and human somatic cells using a single polycistronic vector

(2008) B. W. Carey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA