SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism

Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation

(2011) Andreas M Grabrucker et al.   EMBO JOURNAL

Modulation of Shank3 PDZ Domain Ligand-Binding Affinity by Dimerization

(2010) Wendy S. Iskenderian-Epps et al.   CHEMBIOCHEM

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

(2010) Simone Berkel et al.   NATURE GENETICS

De novo mutations in the gene encoding the synaptic scaffolding proteinSHANK3in patients ascertained for schizophrenia

(2010) Julie Gauthier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Key role for gene dosage and synaptic homeostasis in autism spectrum disorders

(2010) Roberto Toro et al.   TRENDS IN GENETICS

CNTNAP2 and NRXN1 Are Mutated in Autosomal-Recessive Pitt-Hopkins-like Mental Retardation and Determine the Level of a Common Synaptic Protein in Drosophila

(2009) Christiane Zweier et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular Architecture of Synaptic Actin Cytoskeleton in Hippocampal Neurons Reveals a Mechanism of Dendritic Spine Morphogenesis

(2009) Farida Korobova et al.   MOLECULAR BIOLOGY OF THE CELL

Familial deletion within NLGN4 associated with autism and Tourette syndrome

(2008) Amy Lawson-Yuen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

N-WASP and the Arp2/3 Complex Are Critical Regulators of Actin in the Development of Dendritic Spines and Synapses

(2008) Adam M. Wegner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Actin-Binding Protein Abp1 Controls Dendritic Spine Morphology and Is Important for Spine Head and Synapse Formation

(2008) A. Haeckel et al.   JOURNAL OF NEUROSCIENCE

Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1

(2008) A. Y. Hung et al.   JOURNAL OF NEUROSCIENCE

Copy-number variations associated with neuropsychiatric conditions

(2008) Edwin H. Cook Jr et al.   NATURE

Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

(2008) Lorenzo A. Cingolani et al.   NATURE REVIEWS NEUROSCIENCE

The Subspine Organization of Actin Fibers Regulates the Structure and Plasticity of Dendritic Spines

(2008) Naoki Honkura et al.   NEURON