Coexistence of two adamantane binding sites in the influenza A M2 ion channel

Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers

(2010) Sarah D. Cady et al.   NATURE

Designing Inhibitors of M2 Proton Channel against H1N1 Swine Influenza Virus

(2010) Qi-Shi Du et al.   PLoS One

Design and Pharmacological Characterization of Inhibitors of Amantadine-Resistant Mutants of the M2 Ion Channel of Influenza A Virus

(2009) Victoria Balannik et al.   BIOCHEMISTRY

Functional Studies and Modeling of Pore-Lining Residue Mutants of the Influenza A Virus M2 Ion Channel

(2009) Victoria Balannik et al.   BIOCHEMISTRY

Binding Hot Spots and Amantadine Orientation in the Influenza A Virus M2 Proton Channel

(2009) Gwo-Yu Chuang et al.   BIOPHYSICAL JOURNAL

Discovery of Spiro-Piperidine Inhibitors and Their Modulation of the Dynamics of the M2 Proton Channel from Influenza A Virus

(2009) Jun Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformational heterogeneity of the M2 proton channel and a structural model for channel activation

(2009) M. Yi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An amantadine-sensitive chimeric BM2 ion channel of influenza B virus has implications for the mechanism of drug inhibition

(2009) Y. Ohigashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel

(2009) C. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of drug inhibition and drug resistance of influenza A M2 channel

(2009) R. M. Pielak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: The Role of Ser31 in Amantadine Binding

(2008) Sarah D. Cady et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure and mechanism of the M2 proton channel of influenza A virus

(2008) Jason R. Schnell et al.   NATURE

Structural basis for the function and inhibition of an influenza virus proton channel

(2008) Amanda L. Stouffer et al.   NATURE

Design and synthesis of bioactive 1,2-annulated adamantane derivatives

(2008) Grigoris Zoidis et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel

(2008) X. Jing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Interplay of Functional Tuning, Drug Resistance, and Thermodynamic Stability in the Evolution of the M2 Proton Channel from the Influenza A Virus

(2008) Amanda L. Stouffer et al.   STRUCTURE

Solid-State NMR and MD Simulations of the Antiviral Drug Amantadine Solubilized in DMPC Bilayers

(2007) Conggang Li et al.   BIOPHYSICAL JOURNAL