Paracrine hedgehog increases the steroidogenic potential of prostate stromal cells in a Gli-dependent manner

Activation of the Androgen Receptor by Intratumoral Bioconversion of Androstanediol to Dihydrotestosterone in Prostate Cancer

(2011) James L. Mohler et al.   CANCER RESEARCH

Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells

(2011) Mengqian Chen et al.   CELL CYCLE

Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants

(2011) Elahe A. Mostaghel et al.   CLINICAL CANCER RESEARCH

Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy

(2011) Changmeng Cai et al.   ENDOCRINE-RELATED CANCER

Mechanisms and functions of Hedgehog signalling across the metazoa

(2011) Philip W. Ingham et al.   NATURE REVIEWS GENETICS

Abiraterone and Increased Survival in Metastatic Prostate Cancer

(2011) Johann S. de Bono et al.   NEW ENGLAND JOURNAL OF MEDICINE

Active sonic hedgehog signaling between androgen independent human prostate cancer cells and normal/benign but not cancer-associated prostate stromal cells

(2011) Katsumi Shigemura et al.   PROSTATE

An update on androgen deprivation therapy for prostate cancer

(2010) Nima Sharifi et al.   ENDOCRINE-RELATED CANCER

Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells

(2010) Mengqian Chen et al.   Molecular Cancer

Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis

(2010) E. Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer

(2010) Monique T. Barakat et al.   TRENDS IN MOLECULAR MEDICINE

Key targets of hormonal treatment of prostate cancer. Part 1: the androgen receptor and steroidogenic pathways

(2009) André N. Vis et al.   BJU INTERNATIONAL

Castration-Resistant Prostate Cancer: Locking Up the Molecular Escape Routes

(2009) R. M. Attar et al.   CLINICAL CANCER RESEARCH

Activation of the Hedgehog pathway in the mouse fetal ovary leads to ectopic appearance of fetal Leydig cells and female pseudohermaphroditism

(2009) Ivraym B. Barsoum et al.   DEVELOPMENTAL BIOLOGY

Prostate cancer stromal cells and LNCaP cells coordinately activate the androgen receptor through synthesis of testosterone and dihydrotestosterone from dehydroepiandrosterone

(2009) Atsushi Mizokami et al.   ENDOCRINE-RELATED CANCER

The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts

(2009) A Shaw et al.   ONCOGENE

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

(2009) L Yang et al.   ONCOGENE

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

(2009) Suzie J. Scales et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Castration-resistant prostate cancer: Targeting androgen metabolic pathways in recurrent disease

(2009) Elahe A. Mostaghel et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant Prostate Cancer

(2008) J. A. Locke et al.   CANCER RESEARCH

Human prostate stromal cells stimulate increased PSA production in DHEA-treated prostate cancer epithelial cells

(2008) Julia T. Arnold et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE