Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2

Integrin-α5β1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation

(2014) Christopher J. Turner et al.   DEVELOPMENTAL BIOLOGY

Pkd1 Regulates Lymphatic Vascular Morphogenesis during Development

(2014) Baptiste Coxam et al.   Cell Reports

Polycystin Signaling Is Required for Directed Endothelial Cell Migration and Lymphatic Development

(2014) Patricia Outeda et al.   Cell Reports

A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy

(2013) René Hägerling et al.   EMBO JOURNAL

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life

(2013) Paul R. Hess et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphorylation Regulates FOXC2-Mediated Transcription in Lymphatic Endothelial Cells

(2013) K. I. Ivanov et al.   MOLECULAR AND CELLULAR BIOLOGY

Trisubstituted Pyrazolopyrimidines as Novel Angiogenesis Inhibitors

(2013) Sabine B. Weitensteiner et al.   PLoS One

Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos

(2012) Y. Yang et al.   BLOOD

An Unexpected Role of Semaphorin3A–Neuropilin-1 Signaling in Lymphatic Vessel Maturation and Valve Formation

(2012) Giorgia Jurisic et al.   CIRCULATION RESEARCH

Semaphorin3A, Neuropilin-1, and PlexinA1 Are Required for Lymphatic Valve Formation

(2012) Karine Bouvrée et al.   CIRCULATION RESEARCH

Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation

(2012) Amélie Sabine et al.   DEVELOPMENTAL CELL

In Vitro Assays Using Primary Embryonic Mouse Lymphatic Endothelial Cells Uncover Key Roles for FGFR1 Signalling in Lymphangiogenesis

(2012) Jan Kazenwadel et al.   PLoS One

Anti-angiogenic effects of purine inhibitors of cyclin dependent kinases

(2011) Johanna Liebl et al.   ANGIOGENESIS

Twice switched at birth: Cell cycle-independent roles of the “neuron-specific” cyclin-dependent kinase 5 (Cdk5) in non-neuronal cells

(2011) Johanna Liebl et al.   CELLULAR SIGNALLING

Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax

(2011) John D. Kanady et al.   DEVELOPMENTAL BIOLOGY

Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves

(2011) R. S. Srinivasan et al.   GENES & DEVELOPMENT

Lymphatic vascular morphogenesis in development, physiology, and disease

(2011) Stefan Schulte-Merker et al.   JOURNAL OF CELL BIOLOGY

Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

(2011) Dontscho Kerjaschki et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation

(2010) P. Uhrin et al.   BLOOD

Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling

(2010) C. C. Bertozzi et al.   BLOOD

Lymphangiogenesis: Molecular Mechanisms and Future Promise

(2010) Tuomas Tammela et al.   CELL

The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells

(2010) Yuefeng Tang et al.   GENESIS

Cyclin-dependent Kinase 5 Regulates Endothelial Cell Migration and Angiogenesis

(2010) Johanna Liebl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis

(2010) Tej K. Pareek et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis

(2009) G. Wei et al.   BLOOD

Integrin-α9 Is Required for Fibronectin Matrix Assembly during Lymphatic Valve Morphogenesis

(2009) Eleni Bazigou et al.   DEVELOPMENTAL CELL

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

(2009) Camilla Norrmén et al.   JOURNAL OF CELL BIOLOGY

Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

(2008) Jianxin Fu et al.   JOURNAL OF CLINICAL INVESTIGATION