A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours

Activation of protein phosphatase 2A tumor suppressor as potential treatment of pancreatic cancer

(2015) Wenwen Chien et al.   Molecular Oncology

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers

(2015) Feng Li et al.   Oncotarget

Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential

(2014) Giorgio Cozza et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Tumour-infiltrating Gr-1+ myeloid cells antagonize senescence in cancer

(2014) Diletta Di Mitri et al.   NATURE

Enhancing Chemotherapy Efficacy in Pten -Deficient Prostate Tumors by Activating the Senescence-Associated Antitumor Immunity

(2014) Alberto Toso et al.   Cell Reports

CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data

(2013) Gabriela Bindea et al.   BIOINFORMATICS

Anticancer efficacy of cisplatin and trichostatin A or 5-aza-2′-deoxycytidine on ovarian cancer

(2013) F Meng et al.   BRITISH JOURNAL OF CANCER

MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models

(2013) C. Tovar et al.   CANCER RESEARCH

Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma

(2013) J. Rader et al.   CLINICAL CANCER RESEARCH

Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia

(2013) L R Martins et al.   LEUKEMIA

T-helper-1-cell cytokines drive cancer into senescence

(2013) Heidi Braumüller et al.   NATURE

Therapeutic modulators of STAT signalling for human diseases

(2013) Gabriella Miklossy et al.   NATURE REVIEWS DRUG DISCOVERY

CK2 Inhibitor CX-4945 Blocks TGF-β1-Induced Epithelial-to-Mesenchymal Transition in A549 Human Lung Adenocarcinoma Cells

(2013) Jiyeon Kim et al.   PLoS One

Protein kinase CK2 inhibitors: a patent review

(2012) Giorgio Cozza et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Clotrimazole Preferentially Inhibits Human Breast Cancer Cell Proliferation, Viability and Glycolysis

(2012) Cristiane M. Furtado et al.   PLoS One

Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer

(2011) Brett S. Carver et al.   CANCER CELL

Mechanistic Analysis of a DNA Damage-Induced, PTEN-Dependent Size Checkpoint in Human Cells

(2011) J.-S. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE

Clotrimazole induces a late G1 cell cycle arrest and sensitizes glioblastoma cells to radiation in vitro

(2010) Hui Liu et al.   ANTI-CANCER DRUGS

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy

(2010) A. Siddiqui-Jain et al.   CANCER RESEARCH

Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development

(2010) F. Peter Guengerich   Drug Metabolism and Pharmacokinetics

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis

(2010) Andrea Alimonti et al.   JOURNAL OF CLINICAL INVESTIGATION

Enhancement of vinorelbine-induced cytotoxicity and apoptosis by clomipramine and lithium chloride in human neuroblastoma cancer cell line SH-SY5Y

(2010) Ayhan Bilir et al.   JOURNAL OF NEURO-ONCOLOGY

Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805

(2010) F. Baffert et al.   MOLECULAR CANCER THERAPEUTICS

Subtle variations in Pten dose determine cancer susceptibility

(2010) Andrea Alimonti et al.   NATURE GENETICS

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

(2010) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2

(2009) Giorgio Cozza et al.   BIOCHEMICAL JOURNAL

Methotrexate-induced senescence in human adenocarcinoma cells is accompanied by induction of p21waf1/cip1 expression and lack of polyploidy

(2009) Magdalena Dabrowska et al.   CANCER LETTERS

Protein Kinase CK2 in Health and Disease

(2009) O. Filhol et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein Kinase CK2 in Health and Disease

(2009) J. H. Trembley et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Tumor Immunobiological Differences in Prostate Cancer between African-American and European-American Men

(2008) T. A. Wallace et al.   CANCER RESEARCH

Estrogen-Dependent Signaling in a Molecularly Distinct Subclass of Aggressive Prostate Cancer

(2008) Sunita R. Setlur et al.   JNCI-Journal of the National Cancer Institute

CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor

(2008) P. P. Scaglioni et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY