Protein kinase CK2 inhibitors: a patent review

Antitumoral activity of allosteric inhibitors of Protein kinase CK2

(2015) Virginie Moucadel et al.   Oncotarget

Structural Determinants of Protein Kinase CK2 Regulation by Autoinhibitory Polymerization

(2012) Graziano Lolli et al.   ACS Chemical Biology

Unprecedented Selectivity and Structural Determinants of a New Class of Protein Kinase CK2 Inhibitors in Clinical Trials for the Treatment of Cancer

(2011) Roberto Battistutta et al.   BIOCHEMISTRY

The Role of the N-Terminal Domain in the Regulation of the “Constitutively Active” Conformation of Protein Kinase CK2α: Insight from a Molecular Dynamics Investigation

(2011) Andrea Cristiani et al.   ChemMedChem

Urolithin as a Converging Scaffold Linking Ellagic acid and Coumarin Analogues: Design of Potent Protein Kinase CK2 Inhibitors

(2011) Giorgio Cozza et al.   ChemMedChem

The Dark Side of Protein Kinase CK2 Inhibition

(2011) G. Cozza et al.   CURRENT MEDICINAL CHEMISTRY

ATP Site-Directed Inhibitors of Protein Kinase CK2: An Update

(2011) S. Sarno et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

A detailed thermodynamic profile of cyclopentyl and isopropyl derivatives binding to CK2 kinase

(2011) Takayoshi Kinoshita et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer

(2011) Fabrice Pierre et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Antitumor Activity of Pyridocarbazole and Benzopyridoindole Derivatives that Inhibit Protein Kinase CK2

(2010) R. Prudent et al.   CANCER RESEARCH

CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy

(2010) A. Siddiqui-Jain et al.   CANCER RESEARCH

Structural basis of CX-4945 binding to human protein kinase CK2

(2010) Andrew D. Ferguson et al.   FEBS LETTERS

Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2

(2009) Giorgio Cozza et al.   BIOCHEMICAL JOURNAL

Cystic fibrosis transmembrane regulator fragments with the Phe508deletion exert a dual allosteric control over the master kinase CK2

(2009) Mario A. Pagano et al.   BIOCHEMICAL JOURNAL

Extraordinary pleiotropy of protein kinase CK2 revealed by weblogo phosphoproteome analysis

(2009) Mauro Salvi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2

(2009) Alessandra Gianoncelli et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library

(2009) Ming-Szu Hung et al.   BMC CANCER

Protein Kinase CK2 in Health and Disease

(2009) R. Battistutta   CELLULAR AND MOLECULAR LIFE SCIENCES

How druggable is protein kinase CK2?

(2009) Giorgio Cozza et al.   MEDICINAL RESEARCH REVIEWS

IKKα Causes Chromatin Modification on Pro-Inflammatory Genes by Cigarette Smoke in Mouse Lung

(2008) Se-Ran Yang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Deacetylases and NF-κB in Redox Regulation of Cigarette Smoke-Induced Lung Inflammation: Epigenetics in Pathogenesis of COPD

(2008) Saravanan Rajendrasozhan et al.   ANTIOXIDANTS & REDOX SIGNALING

The Regulatory β Subunit of Protein Kinase CK2 Contributes to the Recognition of the Substrate Consensus Sequence. A Study with an eIF2β-Derived Peptide†

(2008) Giorgia Poletto et al.   BIOCHEMISTRY

The CK2α/CK2β Interface of Human Protein Kinase CK2 Harbors a Binding Pocket for Small Molecules

(2008) Jennifer Raaf et al.   CHEMISTRY & BIOLOGY

Identification of Polyoxometalates as Nanomolar Noncompetitive Inhibitors of Protein Kinase CK2

(2008) Renaud Prudent et al.   CHEMISTRY & BIOLOGY

Protein Kinase CK2 in Human Diseases

(2008) Barbara Guerra et al.   CURRENT MEDICINAL CHEMISTRY

Expanding the chemical diversity of CK2 inhibitors

(2008) Renaud Prudent et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Identification of chemical inhibitors of protein-kinase CK2 subunit interaction

(2008) Béatrice Laudet et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Evaluation of 4,5,6,7-tetrahalogeno-1H-isoindole-1,3(2H)-diones as inhibitors of human protein kinase CK2

(2007) A.G. Golub et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Structure-based design and synthesis of novel macrocyclic pyrazolo[1,5-a] [1,3,5]triazine compounds as potent inhibitors of protein kinase CK2 and their anticancer activities

(2007) Zhe Nie et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS