Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion

Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection

(2014) D. K. Raj et al.   SCIENCE

Phosphoinositide Metabolism Links cGMP-Dependent Protein Kinase G to Essential Ca2+ Signals at Key Decision Points in the Life Cycle of Malaria Parasites

(2014) Mathieu Brochet et al.   PLOS BIOLOGY

Inhibition ofPlasmodium falciparumCDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development

(2013) Mauro F. Azevedo et al.   BIOCHEMICAL JOURNAL

A thrombospondin structural repeat containing rhoptry protein fromPlasmodium falciparummediates erythrocyte invasion

(2013) Faiza Amber Siddiqui et al.   CELLULAR MICROBIOLOGY

Key molecular events during host cell invasion by Apicomplexan pathogens

(2013) Pushkar Sharma et al.   CURRENT OPINION IN MICROBIOLOGY

Global Analysis of Protein Expression and Phosphorylation of Three Stages of Plasmodium falciparum Intraerythrocytic Development

(2013) Brittany N. Pease et al.   JOURNAL OF PROTEOME RESEARCH

Construction of human activity-based phosphorylation networks

(2013) R. H. Newman et al.   Molecular Systems Biology

Comprehensive Histone Phosphorylation Analysis and Identification of Pf14-3-3 Protein as a Histone H3 Phosphorylation Reader in Malaria Parasites

(2013) Eeshita G. Dastidar et al.   PLoS One

Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress

(2013) Christine R. Collins et al.   PLoS Pathogens

Ca2+-mediated exocytosis of subtilisin-like protease 1: a key step in egress ofPlasmodium falciparummerozoites

(2012) Shalini Agarwal et al.   CELLULAR MICROBIOLOGY

Plasmodiumkinases as targets for new-generation antimalarials

(2012) Isabelle S Lucet et al.   Future Medicinal Chemistry

Characterization ofPlasmodium falciparumCalcium-dependent Protein Kinase 1 (PfCDPK1) and Its Role in Microneme Secretion during Erythrocyte Invasion

(2012) Abhisheka Bansal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Plasmodium falciparum Schizont Phosphoproteome Reveals Extensive Phosphatidylinositol and cAMP-Protein Kinase A Signaling

(2012) Edwin Lasonder et al.   JOURNAL OF PROTEOME RESEARCH

Insights into the Plasmodium falciparum schizont phospho-proteome

(2012) Edwin Lasonder et al.   MICROBES AND INFECTION

Modular evolution of phosphorylation-based signalling systems

(2012) J. Jin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Preface

(2012) T. Hunter et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

An evolutionary perspective on the kinome of malaria parasites

(2012) E. Talevich et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Subcellular Location, Phosphorylation and Assembly into the Motor Complex of GAP45 during Plasmodium falciparum Schizont Development

(2012) Mohd A. Mohd Ridzuan et al.   PLoS One

Spatiotemporal and Functional Characterisation of the Plasmodium falciparum cGMP-Dependent Protein Kinase

(2012) Christine S. Hopp et al.   PLoS One

The Phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii Reveal Unusual Adaptations Within and Beyond the Parasites' Boundaries

(2011) Moritz Treeck et al.   Cell Host & Microbe

Large-scale phosphosite quantification in tissues by a spike-in SILAC method

(2011) Mara Monetti et al.   NATURE METHODS

Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum

(2011) Lev Solyakov et al.   Nature Communications

Quantitative in vivo Analyses Reveal Calcium-dependent Phosphorylation Sites and Identifies a Novel Component of the Toxoplasma Invasion Motor Complex

(2011) Thomas Nebl et al.   PLoS Pathogens

The Systematic Functional Analysis of Plasmodium Protein Kinases Identifies Essential Regulators of Mosquito Transmission

(2010) Rita Tewari et al.   Cell Host & Microbe

Functional Dissection of the Apicomplexan Glideosome Molecular Architecture

(2010) Karine Frénal et al.   Cell Host & Microbe

An essential Aurora-related kinase transiently associates with spindle pole bodies during Plasmodium falciparum erythrocytic schizogony

(2010) Luc Reininger et al.   MOLECULAR MICROBIOLOGY

cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action

(2010) S. H. Francis et al.   PHARMACOLOGICAL REVIEWS

Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development

(2010) M. J. Boyle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Scaffold: A bioinformatic tool for validating MS/MS-based proteomic studies

(2010) Brian C. Searle   PROTEOMICS

A Plant-Like Kinase in Plasmodium falciparum Regulates Parasite Egress from Erythrocytes

(2010) J. D. Dvorin et al.   SCIENCE

Distinct External Signals Trigger Sequential Release of Apical Organelles during Erythrocyte Invasion by Malaria Parasites

(2010) Shailja Singh et al.   PLoS Pathogens

ESG: extended similarity group method for automated protein function prediction

(2009) Meghana Chitale et al.   BIOINFORMATICS

The Malaria Parasite Cyclic GMP-Dependent Protein Kinase Plays a Central Role in Blood-Stage Schizogony

(2009) Helen M. Taylor et al.   EUKARYOTIC CELL

Role of Plasmodium berghei cGMP-dependent Protein Kinase in Late Liver Stage Development

(2009) Adebola Falae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein kinase inhibitors: contributions from structure to clinical compounds

(2009) Louise N. Johnson   QUARTERLY REVIEWS OF BIOPHYSICS

A Cyclic GMP Signalling Module That Regulates Gliding Motility in a Malaria Parasite

(2009) Robert W. Moon et al.   PLoS Pathogens

The Motor Complex ofPlasmodium falciparum

(2008) Judith L. Green et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thar she blows

(2008) May Chiao   Nature Physics

Gametogenesis in Malaria Parasites Is Mediated by the cGMP-Dependent Protein Kinase

(2008) Louisa McRobert et al.   PLOS BIOLOGY