Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer

Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer® therapeutics

(2015) Axel Vater et al.   DRUG DISCOVERY TODAY

Crystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid Ligand

(2014) Amy D. Gelinas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A G-quadruplex–containing RNA activates fluorescence in a GFP-like fluorophore

(2014) Hao Huang et al.   Nature Chemical Biology

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein

(2014) Katherine Deigan Warner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural and functional characterization of human and murine C5a anaphylatoxins

(2014) Janus Asbjørn Schatz-Jakobsen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Duplex–quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer

(2013) Irene Russo Krauss et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A Novel C5a-neutralizing Mirror-image (l-)Aptamer Prevents Organ Failure and Improves Survival in Experimental Sepsis

(2013) Kai Hoehlig et al.   MOLECULAR THERAPY

Targeting complement component 5a promotes vascular integrity and limits airway remodeling

(2013) M. A. Khan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Complement in Multiorgan Failure

(2012) Daniel Rittirsch et al.   Clinical & Developmental Immunology

G-quadruplex DNA Aptamers and their Ligands: Structure, Function and Application

(2012) W. O. Tucker et al.   CURRENT PHARMACEUTICAL DESIGN

Guanine base stacking in G-quadruplex nucleic acids

(2012) Christopher Jacques Lech et al.   NUCLEIC ACIDS RESEARCH

Automated 3D structure composition for large RNAs

(2012) Mariusz Popenda et al.   NUCLEIC ACIDS RESEARCH

Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg

(2012) Goran Bajic et al.   PROTEIN SCIENCE

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The new face of anaphylatoxins in immune regulation

(2011) Wuding Zhou   IMMUNOBIOLOGY

Inhibiting the C5–C5a receptor axis

(2011) Trent M. Woodruff et al.   MOLECULAR IMMUNOLOGY

Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction

(2011) Anh Tuân Phan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of human desArg-C5a

(2010) William J. Cook et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Therapeutic Complement Inhibition: New Developments

(2010) Woodruff Emlen et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments

(2009) Charles Simon Bond et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Complement and its role in innate and adaptive immune responses

(2009) Jason R Dunkelberger et al.   CELL RESEARCH

The role of the anaphylatoxins in health and disease

(2009) Andreas Klos et al.   MOLECULAR IMMUNOLOGY

Complement activation and inhibition: a delicate balance

(2009) A.P. Sjöberg et al.   TRENDS IN IMMUNOLOGY

Structure of the Complement Factor 5a Receptor-Ligand Complex Studied by Disulfide Trapping and Molecular Modeling

(2008) Ian S. Hagemann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Data mining of metal ion environments present in protein structures

(2008) Heping Zheng et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Structure of and influence of a tick complement inhibitor on human complement component 5

(2008) Folmer Fredslund et al.   NATURE IMMUNOLOGY