Novel Insights into the Biology of CLL

Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin

(2010) C. C. Chu et al.   BLOOD

Genetic Susceptibility Variants for Chronic Lymphocytic Leukemia

(2010) S. L. Slager et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Aggressive Chronic Lymphocytic Leukemia with Elevated Genomic Complexity Is Associated with Multiple Gene Defects in the Response to DNA Double-Strand Breaks

(2010) P. Ouillette et al.   CLINICAL CANCER RESEARCH

Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk

(2010) Dalemari Crowther-Swanepoel et al.   NATURE GENETICS

Characterization of structurally defined epitopes recognized by monoclonal antibodies produced by chronic lymphocytic leukemia B cells

(2009) T. Seiler et al.   BLOOD

In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia

(2009) C. Calissano et al.   BLOOD

Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia

(2009) M. Kanduri et al.   BLOOD

Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression

(2009) A. K. Ghosh et al.   BLOOD

Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance

(2009) A. V. Kurtova et al.   BLOOD

Enhanced formation and survival of CD4+CD25hiFoxp3+T-cells in chronic lymphocytic leukemia

(2009) Margot Jak et al.   LEUKEMIA & LYMPHOMA

BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells

(2008) A. Guarini et al.   BLOOD

Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia

(2008) M. Vogler et al.   BLOOD

Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy

(2008) M. Muzio et al.   BLOOD

Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up

(2008) T. Zenz et al.   BLOOD

Expression and function of toll like receptors in chronic lymphocytic leukaemia cells

(2008) Marta Muzio et al.   BRITISH JOURNAL OF HAEMATOLOGY

Integrated Genomic Profiling of Chronic Lymphocytic Leukemia Identifies Subtypes of Deletion 13q14

(2008) P. Ouillette et al.   CANCER RESEARCH

Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia

(2008) Sonia Fabris et al.   GENES CHROMOSOMES & CANCER

A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia

(2008) Maria Chiara Di Bernardo et al.   NATURE GENETICS