Absence of surrogate light chain results in spontaneous autoreactive germinal centres expanding V H 81X-expressing B cells

Surrogate light chain is required for central and peripheral B-cell tolerance and inhibits anti-DNA antibody production by marginal zone B cells

(2015) Weicheng Ren et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pathophysiology of T follicular helper cells in humans and mice

(2015) Hideki Ueno et al.   NATURE IMMUNOLOGY

The imperfect control of self-reactive germinal center B cells

(2014) Robert Brink   CURRENT OPINION IN IMMUNOLOGY

Persistent Antigen and Germinal Center B Cells Sustain T Follicular Helper Cell Responses and Phenotype

(2013) Dirk Baumjohann et al.   IMMUNITY

The link between antibodies to OxLDL and natural protection against pneumococci depends on D H gene conservation

(2013) Andre M. Vale et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular Basis of 9G4 B Cell Autoreactivity in Human Systemic Lupus Erythematosus

(2013) C. Richardson et al.   JOURNAL OF IMMUNOLOGY

Diversity Among Memory B Cells: Origin, Consequences, and Utility

(2013) D. Tarlinton et al.   SCIENCE

T Follicular Helper Cell Dynamics in Germinal Centers

(2013) Z. Shulman et al.   SCIENCE

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

The role of somatic hypermutation in the generation of pathogenic antibodies in SLE

(2012) Kristin Schroeder et al.   AUTOIMMUNITY

Self-recognition and clonal selection: autoreactivity drives the generation of B cells

(2012) Sebastian Herzog et al.   CURRENT OPINION IN IMMUNOLOGY

A germinal center–independent pathway generates unswitched memory B cells early in the primary response

(2012) Justin J. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Efficient generation of B lymphocytes by recognition of self-antigens

(2011) Cathrin Eschbach et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers

(2011) Xiaoming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Requirement for complement in antibody responses is not explained by the classic pathway activator IgM

(2011) C. Rutemark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of B cell autoimmunity in SLE

(2011) Thomas Dörner et al.   ARTHRITIS RESEARCH & THERAPY

What happens before the onset of rheumatoid arthritis?

(2010) Solbritt Rantapää-Dahlqvist   CURRENT OPINION IN RHEUMATOLOGY

T cells and follicular dendritic cells in germinal center B-cell formation and selection

(2010) Carola G. Vinuesa et al.   IMMUNOLOGICAL REVIEWS

Plugging the Leaky Pre-B Cell Receptor

(2010) M. E. Conley et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Hierarchy of Maturity of Murine Memory B Cell Subsets

(2010) M. M. Tomayko et al.   JOURNAL OF IMMUNOLOGY

The potential role of VPREB1 gene copy number variation in susceptibility to rheumatoid arthritis

(2010) Seon-Hee Yim et al.   MOLECULAR IMMUNOLOGY

N-linked glycosylation selectively regulates autonomous precursor BCR function

(2010) Rudolf Übelhart et al.   NATURE IMMUNOLOGY

The pre-B cell receptor: turning autoreactivity into self-defense

(2010) Christian Vettermann et al.   TRENDS IN IMMUNOLOGY

Impaired B-cell development at the pre-BII-cell stage in galectin-1-deficient mice due to inefficient pre-BII/stromal cell interactions

(2009) M. Espeli et al.   BLOOD

Tolerance checkpoints in B-cell development: Johnny B good

(2009) Roxane Tussiwand et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12

(2009) Cindy S Ma et al.   IMMUNOLOGY AND CELL BIOLOGY

Cloning and expression of murine Ig genes from single B cells

(2009) Thomas Tiller et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Differential Cytokine Production and Bystander Activation of Autoreactive B Cells in Response to CpG-A and CpG-B Oligonucleotides

(2009) A. M. Avalos et al.   JOURNAL OF IMMUNOLOGY

Influence of microbial environment on autoimmunity

(2009) Alexander V Chervonsky   NATURE IMMUNOLOGY

Checkpoints in lymphocyte development and autoimmune disease

(2009) Harald von Boehmer et al.   NATURE IMMUNOLOGY

Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies

(2009) Isaac T. W. Harley et al.   NATURE REVIEWS GENETICS

B-cell tolerance checkpoints in health and autoimmunity

(2008) Eric Meffre et al.   CURRENT OPINION IN IMMUNOLOGY

Sites and Stages of Autoreactive B Cell Activation and Regulation

(2008) Mark J. Shlomchik   IMMUNITY

RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetes

(2008) Anil K. Panigrahi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH

Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors

(2008) B. Mietzner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Censoring of Autoreactive B Cell Development by the Pre-B Cell Receptor

(2008) R. A. Keenan et al.   SCIENCE