Metal ion and ligand binding of integrin α5β1

An internal ligand-bound, metastable state of a leukocyte integrin, αXβ2

(2014) Mehmet Sen et al.   JOURNAL OF CELL BIOLOGY

The ensemble nature of allostery

(2014) Hesam N. Motlagh et al.   NATURE

How Natalizumab Binds and Antagonizes α4Integrins

(2013) Yamei Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complete integrin headpiece opening in eight steps

(2013) Jieqing Zhu et al.   JOURNAL OF CELL BIOLOGY

αVβ3 Integrin Crystal Structures and Their Functional Implications

(2012) Xianchi Dong et al.   BIOCHEMISTRY

Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor

(2012) Masamichi Nagae et al.   JOURNAL OF CELL BIOLOGY

Structural specializations of α4β7, an integrin that mediates rolling adhesion

(2012) Yamei Yu et al.   JOURNAL OF CELL BIOLOGY

Structure-Guided Design of a High-Affinity Platelet Integrin  IIb 3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS

(2012) J. Zhu et al.   Science Translational Medicine

Integrin inside-out signaling and the immunological synapse

(2011) Timothy A Springer et al.   CURRENT OPINION IN CELL BIOLOGY

Analysis of protein-ligand interactions by fluorescence polarization

(2011) Ana M Rossi et al.   Nature Protocols

Golgi Bypass: Skirting Around the Heart of Classical Secretion

(2011) A. G. Grieve et al.   Cold Spring Harbor Perspectives in Biology

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Closed headpiece of integrin  IIb 3 and its complex with an  IIb 3-specific antagonist that does not induce opening

(2010) J. Zhu et al.   BLOOD

Structure of an integrin with an αI domain, complement receptor type 4

(2009) Can Xie et al.   EMBO JOURNAL

The Structure of a Receptor with Two Associating Transmembrane Domains on the Cell Surface: Integrin αIIbβ3

(2009) Jieqing Zhu et al.   MOLECULAR CELL

Structural basis for selectin mechanochemistry

(2009) T. A. Springer   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for distinctive recognition of fibrinogen γC peptide by the platelet integrin αIIbβ3

(2008) Timothy A. Springer et al.   JOURNAL OF CELL BIOLOGY

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

(2008) Jianghai Zhu et al.   MOLECULAR CELL