Cyst formation following disruption of intracellular calcium signaling

The number and location of EF hand motifs dictates the calcium dependence of polycystin-2 function

(2014) Ivana Y. Kuo et al.   FASEB JOURNAL

Tissue-engineered kidney disease models

(2013) Teresa M. DesRochers et al.   ADVANCED DRUG DELIVERY REVIEWS

Frequency decoding of calcium oscillations

(2013) Erik Smedler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Strategies Targeting cAMP Signaling in the Treatment of Polycystic Kidney Disease

(2013) V. E. Torres et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Macrophages promote polycystic kidney disease progression

(2013) Katherine I Swenson-Fields et al.   KIDNEY INTERNATIONAL

Direct recording and molecular identification of the calcium channel of primary cilia

(2013) Paul G. DeCaen et al.   NATURE

Primary cilia are specialized calcium signalling organelles

(2013) Markus Delling et al.   NATURE

Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease

(2013) Ming Ma et al.   NATURE GENETICS

Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity

(2013) Teresa M. DesRochers et al.   PLoS One

The regulation of cystogenesis in a tissue engineered kidney disease system by abnormal matrix interactions

(2012) Balajikarthick Subramanian et al.   BIOMATERIALS

Polycystin-1 and polycystin-2 are both required to amplify inositol-trisphosphate-induced Ca2+ release

(2012) D. Mekahli et al.   CELL CALCIUM

CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD

(2012) Nikolay O. Bukanov et al.   CELL CYCLE

The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies

(2012) Junmin Pan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ion Channels in Renal Disease

(2012) Ivana Y. Kuo et al.   CHEMICAL REVIEWS

Calcium-induced Conformational Changes in C-terminal Tail of Polycystin-2 Are Necessary for Channel Gating

(2012) Andjelka S. Ćelić et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cilia at the Node of Mouse Embryos Sense Fluid Flow for Left-Right Determination via Pkd2

(2012) S. Yoshiba et al.   SCIENCE

Increasing extracellular matrix collagen level and MMP activity induces cyst development in polycystic kidney disease

(2012) Bin Liu et al.   BMC Nephrology

Ciliary resorption modulates G1length and cell cycle progression

(2011) Ching-Hwa Sung et al.   CELL CYCLE

Cilia and cell cycle re-entry

(2011) Sehyun Kim et al.   CELL CYCLE

Type 2 inositol 1,4,5-trisphosphate receptor modulates bile salt export pump activity in rat hepatocytes

(2011) Emma A. Kruglov et al.   HEPATOLOGY

Altered store operated calcium entry increases cyclic 3′,5′-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes

(2011) Carlo Spirli et al.   HEPATOLOGY

Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

(2011) V. Takiar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclic AMP-mediated cyst expansion

(2010) Darren P. Wallace   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma

(2010) Kazunori Shibao et al.   CELL CALCIUM

Polycystin-2 Activation by Inositol 1,4,5-Trisphosphate-induced Ca2+Release Requires Its Direct Association with the Inositol 1,4,5-Trisphosphate Receptor in a Signaling Microdomain

(2010) Eva Sammels et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tissue-Engineered Three-Dimensional In Vitro Models for Normal and Diseased Kidney

(2010) Balajikarthick Subramanian et al.   TISSUE ENGINEERING PART A

Polycystins and Primary Cilia: Primers for Cell Cycle Progression

(2009) Jing Zhou   Annual Review of Physiology

TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum

(2009) Tomasz Wegierski et al.   EMBO JOURNAL

Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks

(2009) Xuewen Song et al.   HUMAN MOLECULAR GENETICS

Ciliar functions in the nephron

(2009) Lise Rodat-Despoix et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Calcium Pumps in Health and Disease

(2009) Marisa Brini et al.   PHYSIOLOGICAL REVIEWS

Ciliary dysfunction in polycystic kidney disease: an emerging model with polarizing potential

(2008) Robert et al.   Frontiers in Bioscience-Landmark