Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 34, Pages 12354-12359
Publisher
Proceedings of the National Academy of Sciences
Online
2014-07-22
DOI
10.1073/pnas.1406999111
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Insights into the Biosynthesis of 12-Membered Resorcylic Acid Lactones from Heterologous Production in Saccharomyces cerevisiae
- (2014) Yuquan Xu et al. ACS Chemical Biology
- Recent progress regarding the bioactivities, biosynthesis and synthesis of naturally occurring resorcinolic macrolides
- (2014) Jing Xu et al. ACTA PHARMACOLOGICA SINICA
- Rational Domain Swaps Reveal Insights about Chain Length Control by Ketosynthase Domains in Fungal Nonreducing Polyketide Synthases
- (2014) Ting Liu et al. ORGANIC LETTERS
- Combinatorial Domain Swaps Provide Insights into the Rules of Fungal Polyketide Synthase Programming and the Rational Synthesis of Non-Native Aromatic Products
- (2013) Anna L. Vagstad et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Multifactorial Control of Iteration Events in a Modular Polyketide Assembly Line
- (2013) Benjamin Busch et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Characterization of the Biosynthetic Genes for 10,11-Dehydrocurvularin, a Heat Shock Response-Modulating Anticancer Fungal Polyketide from Aspergillus terreus
- (2013) Yuquan Xu et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Steps towards the synthetic biology of polyketide biosynthesis
- (2013) Matthew Cummings et al. FEMS MICROBIOLOGY LETTERS
- Thioesterase Domains of Fungal Nonreducing Polyketide Synthases Act as Decision Gates during Combinatorial Biosynthesis
- (2013) Yuquan Xu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Rational reprogramming of fungal polyketide first-ring cyclization
- (2013) Y. Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Merging Chemical Synthesis and Biosynthesis: A New Chapter in the Total Synthesis of Natural Products and Natural Product Libraries
- (2012) Andreas Kirschning et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Monocillin II Inhibits Human Breast Cancer Growth Partially by Inhibiting MAPK Pathways and CDK2 Thr160 Phosphorylation
- (2012) Huanhuan Wei et al. CHEMBIOCHEM
- Demonstration of Starter Unit Interprotein Transfer from a Fatty Acid Synthase to a Multidomain, Nonreducing Polyketide Synthase
- (2012) Jennifer Foulke-Abel et al. CHEMBIOCHEM
- Characterization of a Fungal Thioesterase Having Claisen Cyclase and Deacetylase Activities in Melanin Biosynthesis
- (2012) Anna L. Vagstad et al. CHEMISTRY & BIOLOGY
- Synthetic biological approaches to natural product biosynthesis
- (2012) Jaclyn M Winter et al. CURRENT OPINION IN BIOTECHNOLOGY
- Bioengineering natural product biosynthetic pathways for therapeutic applications
- (2012) Ming-Cheng Wu et al. CURRENT OPINION IN BIOTECHNOLOGY
- Expanding nature's small molecule diversity via in vitro biosynthetic pathway engineering
- (2012) Seok Joon Kwon et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Combinatorial biosynthesis of polyketides—a perspective
- (2012) Fong T Wong et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Geopyxins A–E, ent-Kaurane Diterpenoids from Endolichenic Fungal Strains Geopyxis aff. majalis and Geopyxis sp. AZ0066: Structure–Activity Relationships of Geopyxins and Their Analogues
- (2012) E. M. Kithsiri Wijeratne et al. JOURNAL OF NATURAL PRODUCTS
- Navigating the Fungal Polyketide Chemical Space: From Genes to Molecules
- (2012) Yit-Heng Chooi et al. JOURNAL OF ORGANIC CHEMISTRY
- A fungal ketoreductase domain that displays substrate-dependent stereospecificity
- (2012) Hui Zhou et al. Nature Chemical Biology
- Using the Heat-Shock Response To Discover Anticancer Compounds that Target Protein Homeostasis
- (2011) Sandro Santagata et al. ACS Chemical Biology
- The rise, fall and reinvention of combinatorial chemistry
- (2011) Thomas Kodadek CHEMICAL COMMUNICATIONS
- Natural product-like synthetic libraries
- (2011) Gemma L Thomas et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Engineering of an “Unnatural” Natural Product by Swapping Polyketide Synthase Domains inAspergillus nidulans
- (2011) Ting Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Classification, Prediction, and Verification of the Regioselectivity of Fungal Polyketide Synthase Product Template Domains
- (2010) Yanran Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Insights into Radicicol Biosynthesis via Heterologous Synthesis of Intermediates and Analogs
- (2010) Hui Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enzymatic Synthesis of Resorcylic Acid Lactones by Cooperation of Fungal Iterative Polyketide Synthases Involved in Hypothemycin Biosynthesis
- (2010) Hui Zhou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- New insights into the formation of fungal aromatic polyketides
- (2010) Jason M. Crawford et al. NATURE REVIEWS MICROBIOLOGY
- Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis
- (2010) T. P. Korman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Determination of the extent of phosphopantetheinylation of polyketide synthases expressed in Escherichia coli and Saccharomyces cerevisiae
- (2009) Ka Kit Michael Lee et al. ANALYTICAL BIOCHEMISTRY
- A Thioesterase from an Iterative Fungal Polyketide Synthase Shows Macrocyclization and Cross Coupling Activity and May Play a Role in Controlling Iterative Cycling through Product Offloading
- (2009) Meng Wang et al. BIOCHEMISTRY
- Hsp90 Inhibition with Resorcylic Acid Lactones (RALs)
- (2009) Nicolas Winssinger et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization
- (2009) Jason M. Crawford et al. NATURE
- Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase
- (2009) S. M. Ma et al. SCIENCE
- Genes for the Biosynthesis of the Fungal Polyketides Hypothemycin from Hypomyces subiculosus and Radicicol from Pochonia chlamydosporia
- (2008) C. D. Reeves et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Functional Characterization of the Biosynthesis of Radicicol, an Hsp90 Inhibitor Resorcylic Acid Lactone from Chaetomium chiversii
- (2008) Shuhao Wang et al. CHEMISTRY & BIOLOGY
- A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
- (2008) H. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More