Dimerization and Heme Binding Are Conserved in Amphibian and Starfish Homologues of the microRNA Processing Protein DGCR8

Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing

(2012) I. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caspases cleave and inhibit the microRNA processing protein DiGeorge Critical Region 8

(2012) Ming Gong et al.   PROTEIN SCIENCE

Uncoupling of complex regulatory patterning during evolution of larval development in echinoderms

(2011) Kristen A Yankura et al.   BMC BIOLOGY

DiGeorge Critical Region 8 (DGCR8) Is a Double-cysteine-ligated Heme Protein

(2011) Ian Barr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex

(2011) Claude M Schofield et al.   Neural Development

Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex

(2011) K. Fenelon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Structure of the dimerization domain of DiGeorge Critical Region 8

(2010) Rachel Senturia et al.   PROTEIN SCIENCE

DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures

(2010) M. Faller et al.   RNA

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

(2008) Kimberly L Stark et al.   NATURE GENETICS

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols

DGCR8-dependent microRNA biogenesis is essential for skin development

(2008) R. Yi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA