Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy
Published 2013 View Full Article
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Title
Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 110, Issue 36, Pages E3445-E3454
Publisher
Proceedings of the National Academy of Sciences
Online
2013-08-15
DOI
10.1073/pnas.1303002110
References
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Related references
Note: Only part of the references are listed.- Stapled Peptides with Improved Potency and Specificity That Activate p53
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- Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis
- (2011) Young-Woo Kim et al. Nature Protocols
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- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
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- Structure-based Design of High Affinity Peptides Inhibiting the Interaction of p53 with MDM2 and MDMX
- (2009) Jason Phan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting Mdm2 and Mdmx in Cancer Therapy: Better Living through Medicinal Chemistry?
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- Direct inhibition of the NOTCH transcription factor complex
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- Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX
- (2009) M. Pazgier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dual role of proapoptotic BAD in insulin secretion and beta cell survival
- (2008) Nika N Danial et al. NATURE MEDICINE
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