Molecular determinants of PI3K -mediated activation downstream of G-protein-coupled receptors (GPCRs)
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Title
Molecular determinants of PI3K -mediated activation downstream of G-protein-coupled receptors (GPCRs)
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 110, Issue 47, Pages 18862-18867
Publisher
Proceedings of the National Academy of Sciences
Online
2013-11-05
DOI
10.1073/pnas.1304801110
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- (2012) Martial Rey et al. BIOCHEMISTRY
- Targeting Nonclassical Oncogenes for Therapy in T-ALL
- (2012) Prem S. Subramaniam et al. CANCER CELL
- Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110 (PIK3CA)
- (2012) J. E. Burke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- G Protein-Coupled Receptor-Mediated Activation of p110 by G Is Required for Cellular Transformation and Invasiveness
- (2012) H. A. Dbouk et al. Science Signaling
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- PI3Kγ Mediates Kaposi's Sarcoma-Associated Herpesvirus vGPCR-Induced Sarcomagenesis
- (2011) Daniel Martin et al. CANCER CELL
- Receptor Tyrosine Kinases and TLR/IL1Rs Unexpectedly Activate Myeloid Cell PI3Kγ, A Single Convergent Point Promoting Tumor Inflammation and Progression
- (2011) Michael C. Schmid et al. CANCER CELL
- Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism
- (2011) Xuxiao Zhang et al. MOLECULAR CELL
- Integrating Cardiac PIP3 and cAMP Signaling through a PKA Anchoring Function of p110γ
- (2011) Alessia Perino et al. MOLECULAR CELL
- Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
- (2011) Ka Young Chung et al. NATURE
- Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization
- (2011) Mikyung Kim et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis
- (2011) J A Brazzatti et al. ONCOGENE
- Structural Basis for Activation and Inhibition of Class I Phosphoinositide 3-Kinases
- (2011) Oscar Vadas et al. Science Signaling
- Dynamics of the Phosphoinositide 3-Kinase p110δ Interaction with p85α and Membranes Reveals Aspects of Regulation Distinct from p110α
- (2011) John E. Burke et al. STRUCTURE
- Phosphoinositide-3 Kinase γ Activity Contributes to Sepsis and Organ Damage by Altering Neutrophil Recruitment
- (2010) Erica L. Martin et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Key Role of Phosphoinositide 3-Kinase Class IB in Pancreatic Cancer
- (2010) C. E. Edling et al. CLINICAL CANCER RESEARCH
- Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34
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- Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110
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- A frequent kinase domain mutation that changes the interaction between PI3K and the membrane
- (2009) D. Mandelker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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