Protein kinase Cβ as a therapeutic target stabilizing blood–brain barrier disruption in experimental autoimmune encephalomyelitis

Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models

(2012) Yukio Takeshita et al.   IMMUNOLOGICAL REVIEWS

Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier

(2012) Leslie L Muldoon et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Blood-Brain Barrier Alterations in the Cerebral Cortex in Experimental Autoimmune Encephalomyelitis

(2012) Mariella Errede et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Preclinical Retinal Neurodegeneration in a Model of Multiple Sclerosis

(2012) R. Fairless et al.   JOURNAL OF NEUROSCIENCE

Going Against the Tide – How Encephalitogenic T Cells Breach the Blood-Brain Barrier

(2012) Ruth Lyck et al.   JOURNAL OF VASCULAR RESEARCH

Immune-related GTPase Irgm1 exacerbates experimental auto-immune encephalomyelitis by promoting the disruption of blood–brain barrier and blood–cerebrospinal fluid barrier

(2012) Chaodong Wang et al.   MOLECULAR IMMUNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Alemtuzumab more effective than interferon  -1a at 5-year follow-up of CAMMS223 Clinical Trial

(2012) A. J. Coles et al.   NEUROLOGY

Interferon-  Therapy Against EAE Is Effective Only When Development of the Disease Depends on the NLRP3 Inflammasome

(2012) M. Inoue et al.   Science Signaling

Claudin-1 induced sealing of blood–brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis

(2011) Friederike Pfeiffer et al.   ACTA NEUROPATHOLOGICA

Evolution of the blood-brain barrier in newly forming multiple sclerosis lesions

(2011) María I. Gaitán et al.   ANNALS OF NEUROLOGY

Tight Junctions in Brain Barriers During Central Nervous System Inflammation

(2011) Caroline Coisne et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of the inflammatory response of vascular endothelial cells by EPAC1

(2011) Euan Parnell et al.   BRITISH JOURNAL OF PHARMACOLOGY

Blockade of the kinin receptor B1 protects from autoimmune CNS disease by reducing leukocyte trafficking

(2011) Kerstin Göbel et al.   JOURNAL OF AUTOIMMUNITY

Pathway inhibition: emerging molecular targets for treating glioblastoma

(2011) W. Wick et al.   NEURO-ONCOLOGY

Calcium-Dependent Isoforms of Protein Kinase C Mediate Posttetanic Potentiation at the Calyx of Held

(2011) Diasynou Fioravante et al.   NEURON

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

Blockade of PKC-beta protects HUVEC from advanced glycation end products induced inflammation

(2010) Youhua Xu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activation of PKC Isoform βI at the Blood–Brain Barrier Rapidly Decreases P-Glycoprotein Activity and Enhances Drug Delivery to the Brain

(2010) Robert R Rigor et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Protein Kinase C Activation Modulates Reversible Increase in Cortical Blood–Brain Barrier Permeability and Tight Junction Protein Expression during Hypoxia and Posthypoxic Reoxygenation

(2010) Colin L Willis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Angiotensin II sustains brain inflammation in mice via TGF-β

(2010) Tobias V. Lanz et al.   JOURNAL OF CLINICAL INVESTIGATION

Phase III Study of Enzastaurin Compared With Lomustine in the Treatment of Recurrent Intracranial Glioblastoma

(2010) Wolfgang Wick et al.   JOURNAL OF CLINICAL ONCOLOGY

Blood–brain barrier disruption and enhanced vascular permeability in the multiple sclerosis model EAE

(2010) Jami Bennett et al.   JOURNAL OF NEUROIMMUNOLOGY

Repetitive Pertussis Toxin Promotes Development of Regulatory T Cells and Prevents Central Nervous System Autoimmune Disease

(2010) Martin S. Weber et al.   PLoS One

The role of protein kinase C in the opening of blood–brain barrier induced by electromagnetic pulse

(2010) Lian-Bo Qiu et al.   TOXICOLOGY

Cellular mechanisms of IL-17-induced blood-brain barrier disruption

(2009) Jula Huppert et al.   FASEB JOURNAL

Role of PKCβII and PKCδ in blood–brain barrier permeability during aglycemic hypoxia

(2009) Young-Ae Kim et al.   NEUROSCIENCE LETTERS

Wnt/ -catenin signaling is required for CNS, but not non-CNS, angiogenesis

(2009) R. Daneman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown

(2009) Azeb Tadesse Argaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt/β-catenin signaling controls development of the blood–brain barrier

(2008) Stefan Liebner et al.   JOURNAL OF CELL BIOLOGY

A phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory mantle cell lymphoma

(2007) F. Morschhauser et al.   ANNALS OF ONCOLOGY