Crucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation

The Membrane Fusion Enigma: SNAREs, Sec1/Munc18 Proteins, and Their Accomplices—Guilty as Charged?

(2012) Josep Rizo et al.   Annual Review of Cell and Developmental Biology

Munc18b/STXBP2 is required for platelet secretion

(2012) R. Al Hawas et al.   BLOOD

Hemophagocytic lymphohistiocytosis in syntaxin-11-deficient mice: T-cell exhaustion limits fatal disease

(2012) T. Kogl et al.   BLOOD

Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion

(2012) S. Ye et al.   BLOOD

Munc18-1 mutations that strongly impair SNARE-complex binding support normal synaptic transmission

(2012) Marieke Meijer et al.   EMBO JOURNAL

Syntaxin 11 is required for NK and CD8+T-cell cytotoxicity and neutrophil degranulation

(2012) Orietta D'Orlando et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular machines governing exocytosis of synaptic vesicles

(2012) Reinhard Jahn et al.   NATURE

Low-resolution solution structures of Munc18:Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide

(2012) M. P. Christie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The munc13-4-rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane

(2011) E. D. Elstak et al.   BLOOD

Munc18-1 domain-1 controls vesicle docking and secretion by interacting with syntaxin-1 and chaperoning it to the plasma membrane

(2011) Gayoung A. Han et al.   MOLECULAR BIOLOGY OF THE CELL

Syntaxin 11 Binds Vti1b and Regulates Late Endosome to Lysosome Fusion in Macrophages

(2011) Carolin Offenhäuser et al.   TRAFFIC

Spectrum of clinical presentations in familial hemophagocytic lymphohistiocytosis type 5 patients with mutations in STXBP2

(2010) M. Meeths et al.   BLOOD

Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis

(2010) Q. Ren et al.   BLOOD

SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion

(2010) Jingshi Shen et al.   JOURNAL OF CELL BIOLOGY

STXBP2 mutations in children with familial haemophagocytic lymphohistiocytosis type 5

(2010) V. Cetica et al.   JOURNAL OF MEDICAL GENETICS

Munc18-1 as a key regulator of neurosecretion

(2010) Gayoung A. Han et al.   JOURNAL OF NEUROCHEMISTRY

Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex

(2010) S. S. Rathore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL-5) Is Caused by Mutations in Munc18-2 and Impaired Binding to Syntaxin 11

(2009) Udo zur Stadt et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Abrogating Munc18-1-SNARE Complex Interaction Has Limited Impact on Exocytosis in PC12 Cells

(2009) Nancy T. Malintan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells

(2009) Marjorie Côte et al.   JOURNAL OF CLINICAL INVESTIGATION

Rescue of Munc18-1 and -2 Double Knockdown Reveals the Essential Functions of Interaction between Munc18 and Closed Syntaxin in PC12 Cells

(2009) Liping Han et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide

(2008) Pawel Burkhardt et al.   EMBO JOURNAL

UNC-18 Promotes Both the Anterograde Trafficking and Synaptic Function of Syntaxin

(2008) Jason M. McEwen et al.   MOLECULAR BIOLOGY OF THE CELL

SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes

(2008) D. Tareste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Munc18-1 Is Critical for Plasma Membrane Localization of Syntaxin1 but Not of SNAP-25 in PC12 Cells

(2007) Lakshmanan Arunachalam et al.   MOLECULAR BIOLOGY OF THE CELL